CBD Promotes Oral Ulcer Healing via Inhibiting CMPK2-Mediated Inflammasome

Inhibitory Effect of Cannabidiol on the Activation of NLRP3 Inflammasome Is Associated with Its Modulation of the P2X7 Receptor in Human Monocytes

(2020) Chang Liu et al.   JOURNAL OF NATURAL PRODUCTS

Glucose metabolism links astroglial mitochondria to cannabinoid effects

(2020) Daniel Jimenez-Blasco et al.   NATURE

Regulation of HMGB1 release protects chemoradiotherapy-associated mucositis

(2019) Keon-Il Im et al.   Mucosal Immunology

Genome wide analysis for mouth ulcers identifies associations at immune regulatory loci

(2019) Tom Dudding et al.   Nature Communications

Safety, efficacy, and mechanisms of action of cannabinoids in neurological disorders

(2019) Daniel Friedman et al.   LANCET NEUROLOGY

As CBD skyrockets in popularity, scientists scramble to understand how it’s metabolized

(2019) Amber Dance   NATURE MEDICINE

Trial of Apremilast for Oral Ulcers in Behçet’s Syndrome

(2019) Gülen Hatemi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cannabidiol induces antioxidant pathways in keratinocytes by targeting BACH1

(2019) Laura Casares et al.   Redox Biology

A Randomized, Double-blind, Placebo-controlled, Parallel-group, Pilot Study of Cannabidiol-rich Botanical Extract in the Symptomatic Treatment of Ulcerative Colitis

(2018) Peter M Irving et al.   INFLAMMATORY BOWEL DISEASES

Association of the NOD-like receptor 3 (NLRP3 ) gene variability with recurrent aphthous stomatitis in the Czech population

(2018) Simona Slezakova et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Cannabidiol prevents haloperidol-induced vacuos chewing movements and inflammatory changes in mice via PPARγ receptors

(2018) Andreza B. Sonego et al.   BRAIN BEHAVIOR AND IMMUNITY

VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways

(2018) Carmen del Rio et al.   BRITISH JOURNAL OF PHARMACOLOGY

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

(2018) Zhenyu Zhong et al.   NATURE

Effects of cannabidiol, a Cannabis sativa constituent, on oral wound healing process in rats: Clinical and histological evaluation

(2018) Mariana Klein et al.   PHYTOTHERAPY RESEARCH

Cannabidiol: State of the art and new challenges for therapeutic applications

(2017) Simona Pisanti et al.   PHARMACOLOGY & THERAPEUTICS

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

(2016) Xing Liu et al.   NATURE

NLRP3gene polymorphisms in Iranian patients with recurrent aphthous stomatitis

(2015) Alireza Zare Bidoki et al.   JOURNAL OF ORAL PATHOLOGY & MEDICINE

Israel: Research without prejudice

(2015) Emily Sohn   NATURE

Cannabidiol improves lung function and inflammation in mice submitted to LPS-induced acute lung injury

(2014) A. Ribeiro et al.   IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY

Cannabidiol exerts sebostatic and antiinflammatory effects on human sebocytes

(2014) Attila Oláh et al.   JOURNAL OF CLINICAL INVESTIGATION

Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis

(2014) Francisco Ortiz et al.   JOURNAL OF PINEAL RESEARCH

mTOR Inhibition Prevents Epithelial Stem Cell Senescence and Protects from Radiation-Induced Mucositis

(2012) Ramiro Iglesias-Bartolome et al.   Cell Stem Cell

The NLRP3 Inflammasome Detects Encephalomyocarditis Virus and Vesicular Stomatitis Virus Infection

(2011) J. V. Rajan et al.   JOURNAL OF VIROLOGY

Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis

(2011) Daniele De Filippis et al.   PLoS One

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Oral ulcers: clinical aspects. A tool for dermatologists. Part I. Acute ulcers

(2009) M. Muñoz-Corcuera et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Cannabinoids Δ9-Tetrahydrocannabinol and Cannabidiol Differentially Inhibit the Lipopolysaccharide-activated NF-κB and Interferon-β/STAT Proinflammatory Pathways in BV-2 Microglial Cells

(2009) Ewa Kozela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MEFV, TNF1rA, CARD15 and NLRP3 mutation analysis in PFAPA

(2009) Efrat Dagan et al.   RHEUMATOLOGY INTERNATIONAL

The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities

(2009) Tamás Bíró et al.   TRENDS IN PHARMACOLOGICAL SCIENCES