Alendronate-functionalized hypoxia-responsive polymeric micelles for targeted therapy of bone metastatic prostate cancer

Recent advances in bone-targeted therapy

(2020) Chen Shi et al.   PHARMACOLOGY & THERAPEUTICS

PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass

(2020) Dorothea I. H. Müller et al.   Scientific Reports

Endocytosis: The Nanoparticle and Submicron Nanocompounds Gateway into the Cell

(2020) Darío Manzanares et al.   Pharmaceutics

Azo-inserted responsive hybrid liposomes for hypoxia-specific drug delivery

(2020) Mengmeng Long et al.   Acta Biomaterialia

Hypoxia-responsive nanoparticles for tumor-targeted drug delivery

(2020) Yuce Li et al.   CANCER LETTERS

Bone Metastasis Pain, from the Bench to the Bedside

(2019) Federica Aielli et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Low-dose zoledronate for the treatment of bone metastasis secondary to prostate cancer

(2019) Elie Akoury et al.   Cancer Cell International

Engineering of Bone- and CD44-Dual-Targeting Redox-Sensitive Liposomes for the Treatment of Orthotopic Osteosarcoma

(2019) Shuaishuai Feng et al.   ACS Applied Materials & Interfaces

Comparison of hypoxic effects induced by chemical and physical hypoxia on cardiomyocytes

(2019) Ru-Zhou Zhao et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Osteoclasts and tumor cells dual targeting nanoparticle to treat bone metastases of lung cancer

(2019) Shao-bo Bai et al.   Nanomedicine-Nanotechnology Biology and Medicine

Dual-active targeting liposomes drug delivery system for bone metastatic breast cancer: Synthesis and biological evaluation

(2019) Ze Zhao et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Targeted delivery of doxorubicin for the treatment of bone metastasis from breast cancer using alendronate-functionalized graphene oxide nanosheets

(2019) Tung Thanh Pham et al.   JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY

Hypoxia-responsive nanoparticle based drug delivery systems in cancer therapy: An up-to-date review

(2019) Rashmi Kumari et al.   JOURNAL OF CONTROLLED RELEASE

Targeted drug delivery for tumor therapy inside the bone marrow

(2018) Chao-Feng Mu et al.   BIOMATERIALS

Stimuli-responsive nanocarriers for delivery of bone therapeutics – Barriers and progresses

(2018) Pedro Lavrador et al.   JOURNAL OF CONTROLLED RELEASE

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

Dependence of Nanoparticle Toxicity on Their Physical and Chemical Properties

(2018) Alyona Sukhanova et al.   Nanoscale Research Letters

Impact of Particle Size and Polydispersity Index on the Clinical Applications of Lipidic Nanocarrier Systems

(2018) M. Danaei et al.   Pharmaceutics

Multifunctional melanin-like nanoparticles for bone-targeted chemo-photothermal therapy of malignant bone tumors and osteolysis

(2018) Yitong Wang et al.   BIOMATERIALS

Effect on Survival of Androgen Deprivation Therapy Alone Compared to Androgen Deprivation Therapy Combined with Concurrent Radiation Therapy to the Prostate in Patients with Primary Bone Metastatic Prostate Cancer in a Prospective Randomised Clinical Trial: Data from the HORRAD Trial

(2018) Liselotte M.S. Boevé et al.   EUROPEAN UROLOGY

Nitroimidazole derivative incorporated liposomes for hypoxia-triggered drug delivery and enhanced therapeutic efficacy in patient-derived tumor xenografts

(2018) Yi Li et al.   Acta Biomaterialia

Targeted Nanomedicine to Treat Bone Metastasis

(2018) Isaac Adjei et al.   Pharmaceutics

A nano-complex system to overcome antagonistic photo-chemo combination cancer therapy

(2018) Chaemin Lim et al.   JOURNAL OF CONTROLLED RELEASE

Metastatic bone disease: Pathogenesis and therapeutic options

(2018) Stella D'Oronzo et al.   Journal of Bone Oncology

Bisphosphonate-functionalized coordination polymer nanoparticles for the treatment of bone metastatic breast cancer

(2017) Yuanfeng He et al.   JOURNAL OF CONTROLLED RELEASE

Hypoxia and Bone Metastatic Disease

(2017) Rachelle W. Johnson et al.   Current Osteoporosis Reports

Poly(ethylene glycol)- b -poly(lysine) copolymer bearing nitroaromatics for hypoxia-sensitive drug delivery

(2016) Thavasyappan Thambi et al.   Acta Biomaterialia

PEGylation as a strategy for improving nanoparticle-based drug and gene delivery

(2016) Jung Soo Suk et al.   ADVANCED DRUG DELIVERY REVIEWS

Inhibition of bone loss with surface-modulated, drug-loaded nanoparticles in an intraosseous model of prostate cancer

(2016) Isaac M. Adjei et al.   JOURNAL OF CONTROLLED RELEASE

Bone-targeted delivery of nanodiamond-based drug carriers conjugated with alendronate for potential osteoporosis treatment

(2016) Tae-Kyung Ryu et al.   JOURNAL OF CONTROLLED RELEASE

Ligand binding to anti-cancer target CD44 investigated by molecular simulations

(2016) Tin Trung Nguyen et al.   JOURNAL OF MOLECULAR MODELING

Bisphosphonates for cancer treatment: Mechanisms of action and lessons from clinical trials

(2016) Heleen H. Van Acker et al.   PHARMACOLOGY & THERAPEUTICS

Analyzing Subvisible Particles in Protein Drug Products: a Comparison of Dynamic Light Scattering (DLS) and Resonant Mass Measurement (RMM)

(2014) Jainik Panchal et al.   AAPS Journal

RGD peptide conjugated liposomal drug delivery system for enhance therapeutic efficacy in treating bone metastasis from prostate cancer

(2014) Fangfang Wang et al.   JOURNAL OF CONTROLLED RELEASE

Managing bone metastases and reducing skeletal related events in prostate cancer

(2014) Benjamin A. Gartrell et al.   Nature Reviews Clinical Oncology

Development of Azo-Based Fluorescent Probes to Detect Different Levels of Hypoxia

(2013) Wen Piao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anti-Placental Growth Factor Reduces Bone Metastasis by Blocking Tumor Cell Engraftment and Osteoclast Differentiation

(2010) L. Coenegrachts et al.   CANCER RESEARCH

Bisphosphonates: Molecular Mechanisms of Action and Effects on Bone Cells, Monocytes and Macrophages

(2010) A. J. Roelofs et al.   CURRENT PHARMACEUTICAL DESIGN