Homologous Recombination Deficiency in Pancreatic Cancer: A Systematic Review and Prevalence Meta-Analysis

European cancer mortality predictions for the year 2021 with focus on pancreatic and female lung cancer

(2021) G. Carioli et al.   ANNALS OF ONCOLOGY

Olaparib Monotherapy for Previously Treated Pancreatic Cancer With DNA Damage Repair Genetic Alterations Other Than Germline BRCA Variants

(2021) Milind Javle et al.   JAMA Oncology

Genomic Features and Classification of Homologous Recombination Deficient Pancreatic Ductal Adenocarcinoma

(2021) Talia Golan et al.   GASTROENTEROLOGY

Estimated Projection of US Cancer Incidence and Death to 2040

(2021) Lola Rahib et al.   JAMA Network Open

Homologous recombination deficiency (HRD) scoring in pancreatic ductal adenocarcinoma (PDAC) and response to chemotherapy.

(2020) Grainne M. O'Kane et al.   JOURNAL OF CLINICAL ONCOLOGY

Geographic and Ethnic Heterogeneity of Germline BRCA1 or BRCA2 Mutation Prevalence Among Patients With Metastatic Pancreatic Cancer Screened for Entry Into the POLO Trial

(2020) Talia Golan et al.   JOURNAL OF CLINICAL ONCOLOGY

Current and emerging therapies for patients with advanced pancreatic ductal adenocarcinoma: a bright future

(2020) Eric S Christenson et al.   LANCET ONCOLOGY

PARP inhibitors in pancreatic cancer: molecular mechanisms and clinical applications

(2020) Heng Zhu et al.   Molecular Cancer

The repertoire of mutational signatures in human cancer

(2020) Ludmil B. Alexandrov et al.   NATURE

Early detection of pancreatic cancer

(2020) Stephen P Pereira et al.   Lancet Gastroenterology & Hepatology

Increased Rate of Complete Pathologic Response After Neoadjuvant FOLFIRINOX for BRCA Mutation Carriers with Borderline Resectable Pancreatic Cancer

(2020) Talia Golan et al.   ANNALS OF SURGICAL ONCOLOGY

Genomic Methods Identify Homologous Recombination Deficiency in Pancreas Adenocarcinoma and Optimize Treatment Selection

(2020) Wungki Park et al.   CLINICAL CANCER RESEARCH

NCCN Guidelines Insights: Genetic/Familial High-Risk Assessment: Breast, Ovarian, and Pancreatic, Version 1.2020

(2020) Mary B. Daly et al.   Journal of the National Comprehensive Cancer Network

Olaparib for Metastatic Castration-Resistant Prostate Cancer

(2020) Johann de Bono et al.   NEW ENGLAND JOURNAL OF MEDICINE

ESMO recommendations on predictive biomarker testing for homologous recombination deficiency and PARP inhibitor benefit in ovarian cancer

(2020) R.E. Miller et al.   ANNALS OF ONCOLOGY

Targeting DNA Damage Response and Replication Stress in Pancreatic Cancer

(2020) Stephan B. Dreyer et al.   GASTROENTEROLOGY

DNA damage repair as a target in pancreatic cancer: state-of-the-art and future perspectives

(2020) Lukas Perkhofer et al.   GUT

Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer

(2020) Maha Hussain et al.   NEW ENGLAND JOURNAL OF MEDICINE

TBCRC 048: Phase II Study of Olaparib for Metastatic Breast Cancer and Mutations in Homologous Recombination-Related Genes

(2020) Nadine M. Tung et al.   JOURNAL OF CLINICAL ONCOLOGY

Reshaping preoperative treatment of pancreatic cancer in the era of precision medicine

(2020) R. Casolino et al.   ANNALS OF ONCOLOGY

Real-time Targeted Genome Profile Analysis of Pancreatic Ductal Adenocarcinomas Identifies Genetic Alterations that Might be Targeted with Existing Drugs or Used as Biomarkers

(2019) Aatur D. Singhi et al.   GASTROENTEROLOGY

LBA-001Olaparib as maintenance treatment following first-line platinum-based chemotherapy in patients with a germline BRCA mutation and metastatic pancreatic cancer: phase III POLO trial

(2019) T Golan et al.   ANNALS OF ONCOLOGY

Addendum: A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment

(2019) Michael T. Bashford et al.   GENETICS IN MEDICINE

Editorial

(2019) Philip A Beer et al.   ANNALS OF ONCOLOGY

ATM Dysfunction in Pancreatic Adenocarcinoma and Associated Therapeutic Implications

(2019) Samantha A. Armstrong et al.   MOLECULAR CANCER THERAPEUTICS

Platinum response characteristics of patients with pancreatic ductal adenocarcinoma and a germline BRCA1, BRCA2 or PALB2 mutation

(2019) Max M. Wattenberg et al.   BRITISH JOURNAL OF CANCER

Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

(2018) Matthew B. Yurgelun et al.   GENETICS IN MEDICINE

Recapitulating the clinical scenario of BRCA-associated pancreatic cancer in pre-clinical models

(2018) Talia Golan et al.   INTERNATIONAL JOURNAL OF CANCER

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

(2018) Maeve A Lowery et al.   JNCI-Journal of the National Cancer Institute

Real-time genomic characterization of advanced pancreatic cancer to enable precision medicine

(2018) Andrew J Aguirre et al.   Cancer Discovery

Association between homologous recombination repair gene mutations and response to oxaliplatin in pancreatic cancer

(2018) Tomohiro Kondo et al.   Oncotarget

Mutations in BRCA1, BRCA2, and PALB2, and a panel of 50 cancer-associated genes in pancreatic ductal adenocarcinoma

(2018) Shoko Takeuchi et al.   Scientific Reports

Prospective Evaluation of Germline Alterations in Patients With Exocrine Pancreatic Neoplasms

(2018) Maeve A Lowery et al.   JNCI-Journal of the National Cancer Institute

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Prospective Study of Germline Genetic Testing in Incident Cases of Pancreatic Adenocarcinoma

(2018) Randall Brand et al.   CANCER

The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes

(2017) Thomas P. Slavin et al.   Familial Cancer

Hypermutation In Pancreatic Cancer

(2017) Jeremy L. Humphris et al.   GASTROENTEROLOGY

Deleterious Germline Mutations in Patients With Apparently Sporadic Pancreatic Adenocarcinoma

(2017) Koji Shindo et al.   JOURNAL OF CLINICAL ONCOLOGY

Guidelines for Validation of Next-Generation Sequencing–Based Oncology Panels

(2017) Lawrence J. Jennings et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer

(2017) Marilyn M. Li et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

DNA Repair Dysfunction in Pancreatic Cancer: A Clinically Relevant Subtype for Drug Development

(2017) Talia Golan et al.   Journal of the National Comprehensive Cancer Network

HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures

(2017) Helen Davies et al.   NATURE MEDICINE

Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma

(2017) Ashton A. Connor et al.   JAMA Oncology

Consensus on precision medicine for metastatic cancers: a report from the MAP conference: Table 1.

(2016) C. Swanton et al.   ANNALS OF ONCOLOGY

Candidate DNA repair susceptibility genes identified by exome sequencing in high-risk pancreatic cancer

(2016) Alyssa L. Smith et al.   CANCER LETTERS

Penetrance ofATMGene Mutations in Breast Cancer: A Meta-Analysis of Different Measures of Risk

(2016) Monica Marabelli et al.   GENETIC EPIDEMIOLOGY

Pancreatic cancer

(2016) Terumi Kamisawa et al.   LANCET

Genomic analyses identify molecular subtypes of pancreatic cancer

(2016) Peter Bailey et al.   NATURE

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

(2016) Colin C. Pritchard et al.   NEW ENGLAND JOURNAL OF MEDICINE

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

(2016) Jonathan AC Sterne et al.   BMJ-British Medical Journal

ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions

(2016) Jonathan AC Sterne et al.   BMJ-British Medical Journal

Identification of germline genetic mutations in patients with pancreatic cancer

(2015) Erin E. Salo-Mullen et al.   CANCER

Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology

(2015) Sue Richards et al.   GENETICS IN MEDICINE

Germline BRCA Mutations in a Large Clinic-Based Cohort of Patients With Pancreatic Adenocarcinoma

(2015) Spring Holter et al.   JOURNAL OF CLINICAL ONCOLOGY

Targeting the DNA Damage Response in Cancer

(2015) Mark J. O’Connor   MOLECULAR CELL

Whole genomes redefine the mutational landscape of pancreatic cancer

(2015) Nicola Waddell et al.   NATURE

Publication bias in meta-analyses from the Cochrane Database of Systematic Reviews

(2015) Michal Kicinski et al.   STATISTICS IN MEDICINE

Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets

(2015) Agnieszka K. Witkiewicz et al.   Nature Communications

FactoMineR: AnRPackage for Multivariate Analysis

(2015) Sébastien Lê et al.   Journal of Statistical Software

Conducting Meta-Analyses inRwith themetaforPackage

(2015) Wolfgang Viechtbauer   Journal of Statistical Software

BRCA1andBRCA2germline mutations are frequently demonstrated in both high-risk pancreatic cancer screening and pancreatic cancer cohorts

(2014) Aimee L. Lucas et al.   CANCER

A practice guideline from the American College of Medical Genetics and Genomics and the National Society of Genetic Counselors: referral indications for cancer predisposition assessment

(2014) Heather Hampel et al.   GENETICS IN MEDICINE

In meta-analyses of proportion studies, funnel plots were found to be an inaccurate method of assessing publication bias

(2014) James P. Hunter et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes

(2012) David J McBride et al.   JOURNAL OF PATHOLOGY

Pancreatic cancer genomes reveal aberrations in axon guidance pathway genes

(2012) Andrew V. Biankin et al.   NATURE

GRADE guidelines: 7. Rating the quality of evidence—inconsistency

(2011) Gordon H. Guyatt et al.   JOURNAL OF CLINICAL EPIDEMIOLOGY

The role of tandem duplicator phenotype in tumour evolution in high-grade serous ovarian cancer

(2011) Charlotte KY Ng et al.   JOURNAL OF PATHOLOGY

ATM Mutations in Patients with Hereditary Pancreatic Cancer

(2011) Nicholas J. Roberts et al.   Cancer Discovery

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE

BRCAGermline Mutations in Jewish Patients With Pancreatic Adenocarcinoma

(2008) Cristina R. Ferrone et al.   JOURNAL OF CLINICAL ONCOLOGY