FOXR2 Stabilizes MYCN Protein and Identifies Non–MYCN-Amplified Neuroblastoma Patients With Unfavorable Outcome

Extended induction chemotherapy does not improve the outcome for high-risk neuroblastoma patients: results of the randomized open-label GPOH trial NB2004-HR

(2020) F. Berthold et al.   ANNALS OF ONCOLOGY

MYCN amplification and ATRX mutations are incompatible in neuroblastoma

(2020) Maged Zeineldin et al.   Nature Communications

Telomere maintenance mechanisms define clinical outcome in high-risk neuroblastoma

(2020) Balakrishna Koneru et al.   CANCER RESEARCH

EZHIP / CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma

(2019) Jens-Martin Hübner et al.   NEURO-ONCOLOGY

Sleeping Beauty Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors

(2019) Pauline J. Beckmann et al.   CANCER RESEARCH

Risk-adapted therapy and biological heterogeneity in pineoblastoma: integrated clinico-pathological analysis from the prospective, multi-center SJMB03 and SJYC07 trials

(2019) Anthony P. Y. Liu et al.   ACTA NEUROPATHOLOGICA

Forkhead-box R2 promotes metastasis and growth by stimulating angiogenesis and activating hedgehog signaling pathway in ovarian cancer

(2018) Bing Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

A mechanistic classification of clinical phenotypes in neuroblastoma

(2018) Sandra Ackermann et al.   SCIENCE

FOXR2 Promotes the Proliferation, Invasion, and Epithelial‐Mesenchymal Transition in Human Colorectal Cancer Cells

(2017) Sheng-Qiang Lu et al.   ONCOLOGY RESEARCH

MYC Drives a Subset of High-Risk Pediatric Neuroblastomas and Is Activated through Mechanisms Including Enhancer Hijacking and Focal Enhancer Amplification

(2017) Mark W. Zimmerman et al.   Cancer Discovery

FoxR2 promotes glioma proliferation by suppression of the p27 pathway

(2017) Xuejiao Liu et al.   Oncotarget

Molecular Classification Substitutes for the Prognostic Variables Stage, Age, and MYCN Status in Neuroblastoma Risk Assessment

(2017) Carolina Rosswog et al.   NEOPLASIA

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

(2016) Dominik Sturm et al.   CELL

FOXR2 contributes to cell proliferation and malignancy in human hepatocellular carcinoma

(2016) Xiao Wang et al.   TUMOR BIOLOGY

FOXR2 Interacts with MYC to Promote Its Transcriptional Activities and Tumorigenesis

(2016) Xu Li et al.   Cell Reports

MycN Is Critical for the Maintenance of Human Embryonic Stem Cell-Derived Neural Crest Stem Cells

(2016) Jie Ting Zhang et al.   PLoS One

Augmented expression of MYC and/or MYCN protein defines highly aggressive MYC-driven neuroblastoma: a Children’s Oncology Group study

(2015) L L Wang et al.   BRITISH JOURNAL OF CANCER

Advances in Risk Classification and Treatment Strategies for Neuroblastoma

(2015) Navin R. Pinto et al.   JOURNAL OF CLINICAL ONCOLOGY

Telomerase activation by genomic rearrangements in high-risk neuroblastoma

(2015) Martin Peifer et al.   NATURE

TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors

(2015) Linda J Valentijn et al.   NATURE GENETICS

High expression of FOXR2 in breast cancer correlates with poor prognosis

(2015) Haiping Song et al.   TUMOR BIOLOGY

Comparison of RNA-seq and microarray-based models for clinical endpoint prediction

(2015) Wenqian Zhang et al.   GENOME BIOLOGY

Identification of FoxR2 as an Oncogene in Medulloblastoma

(2014) Hideto Koso et al.   CANCER RESEARCH

Forward genetic screen for malignant peripheral nerve sheath tumor formation identifies new genes and pathways driving tumorigenesis

(2013) Eric P Rahrmann et al.   NATURE GENETICS

The genetic landscape of high-risk neuroblastoma

(2013) Trevor J Pugh et al.   NATURE GENETICS

Neuroblastoma and MYCN

(2013) M. Huang et al.   Cold Spring Harbor Perspectives in Medicine

Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma

(2012) Nai-Kong V. Cheung   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Single-vector inducible lentiviral RNAi system for oncology target validation

(2011) Dmitri Wiederschain et al.   CELL CYCLE

Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma

(2011) E E Santo et al.   ONCOGENE

Recent Advances in Neuroblastoma

(2010) John M. Maris   NEW ENGLAND JOURNAL OF MEDICINE

Identification of ALK as a major familial neuroblastoma predisposition gene

(2008) Yaël P. Mossé et al.   NATURE

PTEN-deficient cancers depend on PIK3CB

(2008) S. Wee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct transcriptional MYCN/c-MYC activities are associated with spontaneous regression or malignant progression in neuroblastomas

(2008) Frank Westermann et al.   GENOME BIOLOGY