Phosphorylation of slit diaphragm proteins NEPHRIN and NEPH1 upon binding of HGF promotes podocyte repair

The motor protein Myo1c regulates transforming growth factor-β-signaling and fibrosis in podocytes

(2019) Ehtesham Arif et al.   KIDNEY INTERNATIONAL

Development of a novel cell-based assay to diagnose recurrent focal segmental glomerulosclerosis patients

(2019) Pankaj Srivastava et al.   KIDNEY INTERNATIONAL

Disruption of the exocyst induces podocyte loss and dysfunction

(2019) Deepak Nihalani et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial biogenesis induced by the β2-adrenergic receptor agonist formoterol accelerates podocyte recovery from glomerular injury

(2019) Ehtesham Arif et al.   KIDNEY INTERNATIONAL

Mutations in KIRREL1, a slit diaphragm component, cause steroid-resistant nephrotic syndrome

(2019) Ashish K. Solanki et al.   KIDNEY INTERNATIONAL

The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes

(2019) Ashish K. Solanki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Nephrin Signaling in the Podocyte: An Updated View of Signal Regulation at the Slit Diaphragm and Beyond

(2018) Claire E. Martin et al.   Frontiers in Endocrinology

Crizotinib, a MET inhibitor, inhibits growth, migration, and invasion of breast cancer cells in vitro and synergizes with chemotherapeutic agents

(2017) Nehad Ayoub et al.   OncoTargets and Therapy

Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria

(2017) Ming-Fo Hsu et al.   Scientific Reports

Targeting Neph1 and ZO-1 protein-protein interaction in podocytes prevents podocyte injury and preserves glomerular filtration function

(2017) Amin Sagar et al.   Scientific Reports

Modeling Monogenic Human Nephrotic Syndrome in theDrosophilaGarland Cell Nephrocyte

(2016) Tobias Hermle et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Structural Analysis of the Myo1c and Neph1 Complex Provides Insight into the Intracellular Movement of Neph1

(2016) Ehtesham Arif et al.   MOLECULAR AND CELLULAR BIOLOGY

Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury

(2015) Rakesh Verma et al.   MOLECULAR AND CELLULAR BIOLOGY

Global Shape and Ligand Binding Efficiency of the HIV-1-neutralizing Antibodies Differ from Those of Antibodies That Cannot Neutralize HIV-1

(2014) Ashish K. Solanki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Slit Diaphragm Protein Neph1 and Its Signaling

(2014) Ehtesham Arif et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of hepatocyte growth factor receptor, c-met, in renal tubules is required for renoprotection after acute kidney injury

(2013) Dong Zhou et al.   KIDNEY INTERNATIONAL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Conditional Genetic Elimination of Hepatocyte Growth Factor in Mice Compromises Liver Regeneration after Partial Hepatectomy

(2013) Kari Nejak-Bowen et al.   PLoS One

Solution Structure Analysis of Cytoplasmic Domain of Podocyte Protein Neph1 Using Small/Wide Angle X-ray Scattering (SWAXS)

(2012) Leena Mallik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The tyrosine phosphatase SHP2 regulates recovery of endothelial adherens junctions through control of β-catenin phosphorylation

(2012) Ilse Timmerman et al.   MOLECULAR BIOLOGY OF THE CELL

Motor Protein Myo1c Is a Podocyte Protein That Facilitates the Transport of Slit Diaphragm Protein Neph1 to the Podocyte Membrane

(2011) E. Arif et al.   MOLECULAR AND CELLULAR BIOLOGY

Nephrin Regulates Lamellipodia Formation by Assembling a Protein Complex That Includes Ship2, Filamin and Lamellipodin

(2011) Madhusudan Venkatareddy et al.   PLoS One

Rituximab Targets Podocytes in Recurrent Focal Segmental Glomerulosclerosis

(2011) A. Fornoni et al.   Science Translational Medicine

Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria

(2010) Chunsun Dai et al.   KIDNEY INTERNATIONAL

Preservations of nephrin and synaptopodin by recombinant hepatocyte growth factor in podocytes for the attenuations of foot process injury and albuminuria in nephritic mice

(2010) TAKASHI KATO et al.   NEPHROLOGY

Sns and Kirre, the Drosophila orthologs of Nephrin and Neph1, direct adhesion, fusion and formation of a slit diaphragm-like structure in insect nephrocytes

(2009) S. Zhuang et al.   DEVELOPMENT

Hepatocyte growth factor (HGF) signals through SHP2 to regulate primary mouse myoblast proliferation

(2009) Ju Li et al.   EXPERIMENTAL CELL RESEARCH

A High Affinity Hepatocyte Growth Factor-binding Site in the Immunoglobulin-like Region of Met

(2008) Cristina Basilico et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neph1, a Component of the Kidney Slit Diaphragm, Is Tyrosine-phosphorylated by the Src Family Tyrosine Kinase and Modulates Intracellular Signaling by Binding to Grb2

(2008) Yutaka Harita et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ischemic Injury to Kidney Induces Glomerular Podocyte Effacement and Dissociation of Slit Diaphragm Proteins Neph1 and ZO-1

(2008) Mark C. Wagner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY