The Rise and Fall of Isotonitazene and Brorphine: Two Recent Stars in the Synthetic Opioid Firmament

The same fundamental drivers but differently expressed: what can we learn from comparing the recent experiences with synthetic opioids in the US and Europe?

(2021) Paul Griffiths et al.   ADDICTION

Death associated with brorphine, an emerging novel synthetic opioid

(2021) V. Vohra et al.   CLINICAL TOXICOLOGY

Isotonitazene: Fatal intoxication in three cases involving this unreported novel psychoactive substance in Switzerland

(2021) F. Mueller et al.   FORENSIC SCIENCE INTERNATIONAL

Synthesis, Chemical Characterization, and μ-Opioid Receptor Activity Assessment of the Emerging Group of “Nitazene” 2-Benzylbenzimidazole Synthetic Opioids

(2021) Marthe M. Vandeputte et al.   ACS Chemical Neuroscience

DARK Classics in Chemical Neuroscience: Etonitazene and Related Benzimidazoles

(2021) István Ujváry et al.   ACS Chemical Neuroscience

Metonitazene in the United States—Forensic toxicology assessment of a potent new synthetic opioid using liquid chromatography mass spectrometry

(2021) Alex J. Krotulski et al.   Drug Testing and Analysis

Analytical characterization of “etonitazepyne,” a new pyrrolidinyl‐containing 2‐benzylbenzimidazole opioid sold online

(2021) Peter Blanckaert et al.   Drug Testing and Analysis

Isotonitazene Quantitation and Metabolite Discovery in Authentic Forensic Casework

(2020) Alex J Krotulski et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

In vitro functional characterization of a panel of non-fentanyl opioid new psychoactive substances

(2020) Marthe M. Vandeputte et al.   ARCHIVES OF TOXICOLOGY

First report on brorphine: the next opioid on the deadly new psychoactive substances’ horizon?

(2020) Nick Verougstraete et al.   JOURNAL OF ANALYTICAL TOXICOLOGY

The dawn of a new synthetic opioid era: the need for innovative interventions

(2020) Bryce Pardo et al.   ADDICTION

Brorphine—Investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography‐mass spectrometry

(2020) Alex J. Krotulski et al.   JOURNAL OF FORENSIC SCIENCES

Activity-based reporter assays for the screening of abused substances in biological matrices

(2019) Annelies Cannaert et al.   CRITICAL REVIEWS IN TOXICOLOGY

Sample Mining and Data Mining: Combined Real‐Time and Retrospective Approaches for the Identification of Emerging Novel Psychoactive Substances

(2019) Alex J. Krotulski et al.   JOURNAL OF FORENSIC SCIENCES

Increases in Online Posts About Synthetic Opioids Preceding Increases in Synthetic Opioid Death Rates: a Retrospective Observational Study

(2019) Daniel A. Bowen et al.   JOURNAL OF GENERAL INTERNAL MEDICINE

Report on a novel emerging class of highly potent benzimidazole NPS opioids: chemical and in vitro functional characterization of isotonitazene

(2019) Peter Blanckaert et al.   Drug Testing and Analysis

Fentanyl, fentanyl analogs and novel synthetic opioids: A comprehensive review

(2018) Patil Armenian et al.   NEUROPHARMACOLOGY

Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias

(2018) Nicole M. Kennedy et al.   JOURNAL OF MEDICINAL CHEMISTRY

The search for the “next” euphoric non-fentanil novel synthetic opioids on the illicit drugs market: current status and horizon scanning

(2018) Kirti Kumari Sharma et al.   Forensic Toxicology

Pharmacological Research as a Key Component in Mitigating the Opioid Overdose Crisis

(2018) Michael H. Baumann et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Getting up to speed with the public health and regulatory challenges posed by new psychoactive substances in the information age

(2013) Paul Griffiths et al.   ADDICTION