Design, optimization and pharmacokinetic evaluation of Piribedil loaded solid lipid nanoparticles dispersed in nasal in situ gelling system for effective management of Parkinson’s disease

Pharmacodynamic, pharmacokinetic and physical characterization of cilnidipine loaded solid lipid nanoparticles for oral delivery optimized using the principles of design of experiments

(2020) Rimpy Diwan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Development and validation of rapid and sensitive LC methods with PDA and fluorescence detection for determination of piribedil in rat plasma and brain tissues and their pharmacokinetic application

(2018) Chandra Teja Uppuluri et al.   BIOMEDICAL CHROMATOGRAPHY

Chitosan nanoparticles for the oral delivery of tenofovir disoproxil fumarate: formulation optimization, characterization and ex vivo and in vivo evaluation for uptake mechanism in rats

(2018) Joseph Shailender et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

Evaluation of intranasal delivery route of drug administration for brain targeting

(2018) Franciska Erdő et al.   BRAIN RESEARCH BULLETIN

Comparative pharmacokinetic evaluation of lopinavir and lopinavir-loaded solid lipid nanoparticles in hepatic impaired rat model

(2017) Punna Rao Ravi et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Evidence of nose-to-brain delivery of nanoemulsions: cargoes but not vehicles

(2017) Ejaj Ahmad et al.   Nanoscale

Piribedil for the Treatment of Motor and Non-motor Symptoms of Parkinson Disease

(2016) Santiago Perez-Lloret et al.   CNS DRUGS

Improving drug delivery technology for treating neurodegenerative diseases

(2016) Yahya E. Choonara et al.   Expert Opinion on Drug Delivery

CSF, blood-brain barrier, and brain drug delivery

(2016) William M. Pardridge   Expert Opinion on Drug Delivery

Strategies for drug delivery to the central nervous system by systemic route

(2014) Narayanan Kasinathan et al.   DRUG DELIVERY

Lipid nanoparticles for oral delivery of raloxifene: Optimization, stability, in vivo evaluation and uptake mechanism

(2014) Punna Rao Ravi et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

A hybrid design to optimize preparation of lopinavir loaded solid lipid nanoparticles and comparative pharmacokinetic evaluation with marketed lopinavir/ritonavir coformulation

(2014) Punna Rao Ravi et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Solid lipid nanoparticles for nose to brain delivery of haloperidol: in vitro drug release and pharmacokinetics evaluation

(2014) Mohd Yasir et al.   Acta Pharmaceutica Sinica B

Parkinsonian apathy responds to dopaminergic stimulation of D2/D3 receptors with piribedil

(2013) Stéphane Thobois et al.   BRAIN

Nasalin-situgels for delivery of rasagiline mesylate: improvement in bioavailability and brain localization

(2013) P. R. Ravi et al.   DRUG DELIVERY

Direct nose to brain drug deliveryviaintegrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

(2013) Chandrakantsing Vijaysing Pardeshi et al.   Expert Opinion on Drug Delivery

SLN approach for nose-to-brain delivery of alprazolam

(2012) Alok Pratap Singh et al.   Drug Delivery and Translational Research

Intranasal delivery of biologics to the central nervous system

(2011) Jeffrey J. Lochhead et al.   ADVANCED DRUG DELIVERY REVIEWS

Cell-Penetrating Peptide-Modified Block Copolymer Micelles Promote Direct Brain Delivery via Intranasal Administration

(2011) Takanori Kanazawa et al.   PHARMACEUTICAL RESEARCH

Molecular interaction and localization of tocotrienol-rich fraction (TRF) within the matrices of lipid nanoparticles: Evidence studies by Differential Scanning Calorimetry (DSC) and Proton Nuclear Magnetic Resonance spectroscopy (1H NMR)

(2010) Hazem Ali et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

From the cell to the clinic: A comparative review of the partial D2/D3 receptor agonist and α2-adrenoceptor antagonist, piribedil, in the treatment of Parkinson's disease

(2010) Mark J. Millan   PHARMACOLOGY & THERAPEUTICS

Intranasal delivery to the central nervous system: Mechanisms and experimental considerations

(2009) Shyeilla V. Dhuria et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The blood–brain and the blood–cerebrospinal fluid barriers: function and dysfunction

(2009) Britta Engelhardt et al.   Seminars in Immunopathology

Intranasal delivery bypasses the blood-brain barrier to target therapeutic agents to the central nervous system and treat neurodegenerative disease

(2008) Leah R Hanson et al.   BMC NEUROSCIENCE