Exploratory Metabolomic Analysis Based on Reversed-Phase Liquid Chromatography–Mass Spectrometry to Study an In Vitro Model of Hypoxia-Induced Metabolic Alterations in HK-2 Cells

Plasma metabolites associated with chronic kidney disease and renal function in adults from the Baltimore Longitudinal Study of Aging

(2021) Yuko Yamaguchi et al.   Metabolomics

Comprehensive metabolomic study of the response of HK-2 cells to hyperglycemic hypoxic diabetic-like milieu

(2021) Alberto Valdés et al.   Scientific Reports

A Non-Targeted Capillary Electrophoresis-Mass Spectrometry Strategy to Study Metabolic Differences in an In Vitro Model of High-Glucose Induced Changes in Human Proximal Tubular HK-2 Cells

(2020) Samuel Bernardo-Bermejo et al.   MOLECULES

Relative Hypoxia and Early Diabetic Kidney Disease in Type 1 Diabetes.

(2020) Carissa Vinovskis et al.   DIABETES

Hypoxia-Inducible Factors and the Regulation of Lipid Metabolism

(2019) Ilias Mylonis et al.   Cells

An untargeted metabolomic strategy based on liquid chromatography-mass spectrometry to study high glucose-induced changes in HK-2 cells

(2019) Samuel Bernardo-Bermejo et al.   JOURNAL OF CHROMATOGRAPHY A

Effect of Acetyl-l-carnitine Used for Protection of Neonatal Hypoxic-Ischemic Brain Injury on Acute Kidney Changes in Male and Female Rats

(2019) Andrew G. Wang et al.   NEUROCHEMICAL RESEARCH

Modified Protocol of Harvesting, Extraction, and Normalization Approaches for Gas Chromatography Mass Spectrometry-Based Metabolomics Analysis of Adherent Cells Grown Under High Fetal Calf Serum Conditions

(2019) Raphaela Fritsche-Guenther et al.   Metabolites

Current and future perspectives of functional metabolomics in disease studies–A review

(2018) Min Yan et al.   ANALYTICA CHIMICA ACTA

The glutathione cycle: Glutathione metabolism beyond the γ-glutamyl cycle

(2018) Anand Kumar Bachhawat et al.   IUBMB LIFE

Knowledge-based metabolite annotation tool: CEU Mass Mediator

(2018) Alberto Gil de la Fuente et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Metabolic Response in Rabbit Urine to Occurrence and Relief of Unilateral Ureteral Obstruction

(2018) Zhenzhao Wang et al.   JOURNAL OF PROTEOME RESEARCH

The uremic toxin hippurate promotes endothelial dysfunction via the activation of Drp1-mediated mitochondrial fission

(2018) Mengjie Huang et al.   Redox Biology

Metabolomic analysis of the toxic effect of chronic exposure of cadmium on rat urine

(2017) Shuai Chen et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Metabolomics Study of the Effects of Inflammation, Hypoxia, and High Glucose on Isolated Human Pancreatic Islets

(2017) Marta Garcia-Contreras et al.   JOURNAL OF PROTEOME RESEARCH

Mitochondrial energetics in the kidney

(2017) Pallavi Bhargava et al.   Nature Reviews Nephrology

Accumulation of 5-oxoproline in myocardial dysfunction and the protective effects of OPLAH

(2017) Atze van der Pol et al.   Science Translational Medicine

Renal Hypoxia in CKD; Pathophysiology and Detecting Methods

(2017) Yosuke Hirakawa et al.   Frontiers in Physiology

Simultaneous Determination of Five Specific and Sensitive Nephrotoxicity Biomarkers in Serum and Urine Samples of Four Drug-Induced Kidney Injury Models

(2016) Liqiang Gu et al.   JOURNAL OF CHROMATOGRAPHIC SCIENCE

Hypoxia in health and disease

(2016) Jacques Pouyssegur et al.   MOLECULAR ASPECTS OF MEDICINE

Pharmacological models and approaches for pathophysiological conditions associated with hypoxia and oxidative stress

(2016) Jorge G. Farías et al.   PHARMACOLOGY & THERAPEUTICS

Liquid chromatography–high-resolution mass spectrometry-based cell metabolomics: Experimental design, recommendations, and applications

(2016) Blandine Madji Hounoum et al.   TRAC-TRENDS IN ANALYTICAL CHEMISTRY

Acylcarnitines: potential implications for skeletal muscle insulin resistance

(2015) Céline Aguer et al.   FASEB JOURNAL

Urinary metabolomics and biomarkers of aristolochic acid nephrotoxicity by UPLC-QTOF/HDMS

(2015) Ying-Yong Zhao et al.   Bioanalysis

Hypoxia induces a lipogenic cancer cell phenotype via HIF1α-dependent and -independent pathways

(2015) Alessandro Valli et al.   Oncotarget

Metabolic profiling reveals potential metabolic markers associated with Hypoxia Inducible Factor-mediated signalling in hypoxic cancer cells

(2015) Emily G. Armitage et al.   Scientific Reports

Vitamin B-6

(2015) Patrick J Stover et al.   Advances in Nutrition

Metabolism under hypoxia in Tm1 murine melanoma cells is affected by the presence of galectin-3, a metabolomics approach

(2014) Pedro Bacchi et al.   SpringerPlus

Hippurate: The Natural History of a Mammalian–Microbial Cometabolite

(2013) Hannah J. Lees et al.   JOURNAL OF PROTEOME RESEARCH

Metabolomic Dynamic Analysis of Hypoxia in MDA-MB-231 and the Comparison with Inferred Metabolites from Transcriptomics Data

(2013) I-Lin Tsai et al.   Cancers

Protein-bound uremic toxins in hemodialysis patients measured by liquid chromatography/tandem mass spectrometry and their effects on endothelial ROS production

(2012) Yoshiharu Itoh et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

Cell culture metabolomics: applications and future directions

(2010) Miroslava Čuperlović-Culf et al.   DRUG DISCOVERY TODAY

Hypoxia-induced metabolic shifts in cancer cells: Moving beyond the Warburg effect

(2010) Aalim M. Weljie et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Toxicology effects of Morning Glory Seed in rat: A metabonomic method for profiling of urine metabolic changes

(2010) Chao Ma et al.   JOURNAL OF ETHNOPHARMACOLOGY

Acute administration of 5-oxoproline induces oxidative damage to lipids and proteins and impairs antioxidant defenses in cerebral cortex and cerebellum of young rats

(2010) Carolina Didonet Pederzolli et al.   METABOLIC BRAIN DISEASE