Structure and Dynamics of Meprin β in Complex with a Hydroxamate-Based Inhibitor

Heteroaromatic Inhibitors of the Astacin Proteinases Meprin α, Meprin β and Ovastacin Discovered by a Scaffold‐Hopping Approach

(2020) Kathrin Tan et al.   ChemMedChem

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes

(2019) Florian Peters et al.   FASEB JOURNAL

Tertiary-Amine-Based Inhibitors of the Astacin Protease Meprin α

(2018) Kathrin Tan et al.   ChemMedChem

Structure-Guided Design, Synthesis, and Characterization of Next-Generation Meprin β Inhibitors

(2018) Daniel Ramsbeck et al.   JOURNAL OF MEDICINAL CHEMISTRY

Continuous assays for meprin alpha and beta using prolyl tripeptidyl aminopeptidase (PtP) from Porphyromonas gingivalis

(2018) Anja Schulze et al.   ANALYTICAL BIOCHEMISTRY

Online interactive analysis of protein structure ensembles with Bio3D-web

(2016) Lars Skjærven et al.   BIOINFORMATICS

ff14SB: Improving the Accuracy of Protein Side Chain and Backbone Parameters from ff99SB

(2015) James A. Maier et al.   Journal of Chemical Theory and Computation

Force Field for Mg2+, Mn2+, Zn2+, and Cd2+ Ions That Have Balanced Interactions with Nucleic Acids

(2015) Maria T. Panteva et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Meprin α and meprin β: Procollagen proteinases in health and disease

(2015) Johannes Prox et al.   MATRIX BIOLOGY

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Stock-based detection of protein oligomeric states in jsPISA

(2015) Eugene Krissinel   NUCLEIC ACIDS RESEARCH

Expression, purification and initial characterization of human meprin β from Pichia pastoris

(2015) D. Schlenzig et al.   PROTEIN EXPRESSION AND PURIFICATION

Privateer: software for the conformational validation of carbohydrate structures

(2015) Jon Agirre et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Integrating protein structural dynamics and evolutionary analysis with Bio3D

(2014) Lars Skjærven et al.   BMC BIOINFORMATICS

The metalloproteases meprin α and meprin β: unique enzymes in inflammation, neurodegeneration, cancer and fibrosis

(2013) Claudia Broder et al.   BIOCHEMICAL JOURNAL

Zinc Coordination Spheres in Protein Structures

(2013) Mikko Laitaoja et al.   INORGANIC CHEMISTRY

PTRAJ and CPPTRAJ: Software for Processing and Analysis of Molecular Dynamics Trajectory Data

(2013) Daniel R. Roe et al.   Journal of Chemical Theory and Computation

Rational Design of Particle Mesh Ewald Compatible Lennard-Jones Parameters for +2 Metal Cations in Explicit Solvent

(2013) Pengfei Li et al.   Journal of Chemical Theory and Computation

Taking into Account the Ion-Induced Dipole Interaction in the Nonbonded Model of Ions

(2013) Pengfei Li et al.   Journal of Chemical Theory and Computation

Validation of metal-binding sites in macromolecular structures with the CheckMyMetal web server

(2013) Heping Zheng et al.   Nature Protocols

Metalloproteases meprin   and meprin   are C- and N-procollagen proteinases important for collagen assembly and tensile strength

(2013) C. Broder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functional and structural insights into astacin metallopeptidases

(2012) F. Xavier Gomis-Rüth et al.   BIOLOGICAL CHEMISTRY

Structural basis for the sheddase function of human meprin   metalloproteinase at the plasma membrane

(2012) J. L. Arolas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A standard orientation for metallopeptidases

(2011) F. Xavier Gomis-Rüth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Proteomic Analyses Reveal an Acidic Prime Side Specificity for the Astacin Metalloprotease Family Reflected by Physiological Substrates

(2011) Christoph Becker-Pauly et al.   MOLECULAR & CELLULAR PROTEOMICS

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Meprins, membrane-bound and secreted astacin metalloproteinases

(2008) E STERCHI et al.   MOLECULAR ASPECTS OF MEDICINE

Protonate3D: Assignment of ionization states and hydrogen coordinates to macromolecular structures

(2008) Paul Labute   PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS