Evidence for Biological Age Acceleration and Telomere Shortening in COVID-19 Survivors

Shorter telomere lengths in patients with severe COVID-19 disease

(2021) Raul Sanchez-Vazquez et al.   Aging-US

Epigenetic Evolution of ACE2 and IL-6 Genes: Non-Canonical Interferon-Stimulated Genes Correlate to COVID-19 Susceptibility in Vertebrates

(2021) Eric R. Sang et al.   Genes

Human cardiosphere-derived stromal cells exposed to SARS-CoV-2 evolve into hyper-inflammatory/pro-fibrotic phenotype and produce infective viral particles depending on the levels of ACE2 receptor expression

(2021) Alessandra Amendola et al.   CARDIOVASCULAR RESEARCH

A Review of Persistent Post-COVID Syndrome (PPCS)

(2021) Bryan Oronsky et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Epigenetic age acceleration changes 2 years after antiretroviral therapy initiation in adults with HIV: a substudy of the NEAT001/ANRS143 randomised trial

(2021) Andrés Esteban-Cantos et al.   Lancet HIV

Epigenome-wide association study of COVID-19 severity with respiratory failure

(2021) Manuel Castro de Moura et al.   EBioMedicine

Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study

(2020) Heshui Shi et al.   LANCET INFECTIOUS DISEASES

COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

(2020) Camillo Sargiacomo et al.   Aging-US

Dipeptidyl peptidase-4 (DPP4) inhibition in COVID-19

(2020) Sebastiano Bruno Solerte et al.   ACTA DIABETOLOGICA

Reduction in ACE2 may mediate the prothrombotic phenotype in COVID-19

(2020) Ying X Gue et al.   EUROPEAN HEART JOURNAL

The cardiovascular burden of coronavirus disease 2019 (COVID-19) with a focus on congenital heart disease

(2020) Weiyi Tan et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Incidence of thrombotic complications in critically ill ICU patients with COVID-19

(2020) F.A. Klok et al.   THROMBOSIS RESEARCH

Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice

(2020) Azar Asadi Shahmirzadi et al.   Cell Metabolism

The epigenetic implication in coronavirus infection and therapy

(2020) Sandra Atlante et al.   Clinical Epigenetics

Metabolic reprogramming and epigenetic changes of vital organs in SARS-CoV-2–induced systemic toxicity

(2020) Shen Li et al.   JCI Insight

Diabetes, metabolic disease, and telomere length

(2020) Feifei Cheng et al.   Lancet Diabetes & Endocrinology

CD26/DPP4 - a potential biomarker and target for cancer therapy

(2019) Njanja Enz et al.   PHARMACOLOGY & THERAPEUTICS

Telomere length and cardiovascular disease risk

(2019) Yiqiang Zhan et al.   CURRENT OPINION IN CARDIOLOGY

Evaluation of six blood-based age prediction models using DNA methylation analysis by pyrosequencing

(2019) Antoine Daunay et al.   Scientific Reports

Renin-Angiotensin System and Cardiovascular Functions

(2018) Chia-Hua Wu et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Back to the future: Epigenetic clock plasticity towards healthy aging

(2018) Ken Declerck et al.   MECHANISMS OF AGEING AND DEVELOPMENT

DNA methylation-based biomarkers and the epigenetic clock theory of ageing

(2018) Steve Horvath et al.   NATURE REVIEWS GENETICS

Recent progress, methods and perspectives in forensic epigenetics

(2018) Athina Vidaki et al.   Forensic Science International-Genetics

Identification of senescent cell surface targetable protein DPP4

(2017) Kyoung Mi Kim et al.   GENES & DEVELOPMENT

The vasoprotective axes of the renin-angiotensin system: Physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases

(2017) Xiao C. Li et al.   PHARMACOLOGICAL RESEARCH

Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway

(2017) Masayoshi Suda et al.   PLoS One

Biological Age Predictors

(2017) Juulia Jylhävä et al.   EBioMedicine

Human age estimation from blood using mRNA, DNA methylation, DNA rearrangement, and telomere length

(2016) Dmitry Zubakov et al.   Forensic Science International-Genetics

Slowing ageing by design: the rise of NAD+ and sirtuin-activating compounds

(2016) Michael S. Bonkowski et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Braf, Kras and Helicobacter pylori epigenetic changes-associated chronic gastritis in Egyptian patients with and without gastric cancer

(2016) Dina Sabry et al.   WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY

Improved age determination of blood and teeth samples using a selected set of DNA methylation markers

(2015) Bram Bekaert et al.   Epigenetics

Cytomegalovirus infection accelerates epigenetic aging

(2015) Laura Kananen et al.   EXPERIMENTAL GERONTOLOGY

HIV-1 Infection Accelerates Age According to the Epigenetic Clock

(2015) Steve Horvath et al.   JOURNAL OF INFECTIOUS DISEASES

Accelerated epigenetic aging in brain is associated with pre-mortem HIV-associated neurocognitive disorders

(2015) Andrew J. Levine et al.   JOURNAL OF NEUROVIROLOGY

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

(2014) Carola Weidner et al.   GENOME BIOLOGY

Applications of physiological bases of ageing to forensic sciences. Estimation of age-at-death

(2013) Sara C. Zapico et al.   AGEING RESEARCH REVIEWS

Structure of MERS-CoV spike receptor-binding domain complexed with human receptor DPP4

(2013) Nianshuang Wang et al.   CELL RESEARCH

DNA methylation age of human tissues and cell types

(2013) Steve Horvath   GENOME BIOLOGY

Genome-wide Methylation Profiles Reveal Quantitative Views of Human Aging Rates

(2012) Gregory Hannum et al.   MOLECULAR CELL

Acute respiratory distress syndrome: epidemiology and management approaches

(2012) Allan Walkey et al.   Clinical Epidemiology

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

(2010) Shinsuke Ito et al.   NATURE