A New Perspective on Cancer Therapy: Changing the Treaded Path?

Targeted Repolarization of Tumor‐Associated Macrophages via Imidazoquinoline‐Linked Nanobodies

(2021) Evangelia Bolli et al.   Advanced Science

Resolvin D1 reduces cancer growth stimulating a protective neutrophil-dependent recruitment of anti-tumor monocytes

(2021) Domenico Mattoscio et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Using curcumin to turn the innate immune system against cancer

(2020) Sumit Mukherjee et al.   BIOCHEMICAL PHARMACOLOGY

Pro‐Resolving Lipid Mediators and Anti‐Angiogenic Therapy Exhibit Synergistic Anti‐Tumor Activity via Resolvin Receptor Activation

(2020) Victoria M. Hallisey et al.   FASEB JOURNAL

The role of tumor-associated macrophages (TAMs) in tumor progression and relevant advance in targeted therapy

(2020) Qiyao Yang et al.   Acta Pharmaceutica Sinica B

Re-education of macrophages as a therapeutic strategy in cancer

(2019) Joanna Kowal et al.   Immunotherapy

Harnessing Microglia and Macrophages for the Treatment of Glioblastoma

(2019) Ioanna Prionisti et al.   Frontiers in Pharmacology

A view on drug resistance in cancer

(2019) Neil Vasan et al.   NATURE

More Than Just Attractive: How CCL2 Influences Myeloid Cell Behavior Beyond Chemotaxis

(2019) Martha Gschwandtner et al.   Frontiers in Immunology

TriCurin, a synergistic formulation of curcumin, resveratrol, and epicatechin gallate, repolarizes tumor-associated macrophages and triggers an immune response to cause suppression of HPV+ tumors

(2018) Sumit Mukherjee et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Liposomal TriCurin, A Synergistic Combination of Curcumin, Epicatechin Gallate and Resveratrol, Repolarizes Tumor-Associated Microglia/Macrophages, and Eliminates Glioblastoma (GBM) and GBM Stem Cells

(2018) Sumit Mukherjee et al.   MOLECULES

Repolarization of Tumor-Associated Macrophages in a Genetically Engineered Nonsmall Cell Lung Cancer Model by Intraperitoneal Administration of Hyaluronic Acid-Based Nanoparticles Encapsulating MicroRNA-125b

(2018) Neha N. Parayath et al.   NANO LETTERS

Anti-inflammatory Effects of Curcumin in Microglial Cells

(2018) Yangyang Yu et al.   Frontiers in Pharmacology

Phytosomal curcumin causes natural killer cell-dependent repolarization of glioblastoma (GBM) tumor-associated microglia/macrophages and elimination of GBM and GBM stem cells

(2018) Sumit Mukherjee et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Metformin for Treatment of Fragile X Syndrome and Other Neurological Disorders

(2018) Ilse Gantois et al.   Annual Review of Medicine

Molecular Repolarisation of Tumour-Associated Macrophages

(2018) Floris van Dalen et al.   MOLECULES

Overcoming therapeutic resistance in glioblastoma: the way forward

(2017) Satoru Osuka et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvins suppress tumor growth and enhance cancer therapy

(2017) Megan L. Sulciner et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MUC1 induces acquired chemoresistance by upregulating ABCB1 in EGFR-dependent manner

(2017) Wei Jin et al.   Cell Death & Disease

Unique synergistic formulation of curcumin, epicatechin gallate and resveratrol, tricurin, suppresses HPV E6, eliminates HPV+ cancer cells, and inhibits tumor progression

(2017) Sumit Mukherjee et al.   Oncotarget

CTLA-4 and PD-1 Pathways

(2016) Elizabeth I. Buchbinder et al.   AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS

Deubiquitination and Stabilization of PD-L1 by CSN5

(2016) Seung-Oe Lim et al.   CANCER CELL

CCL2 Produced by the Glioma Microenvironment Is Essential for the Recruitment of Regulatory T Cells and Myeloid-Derived Suppressor Cells

(2016) Alan L. Chang et al.   CANCER RESEARCH

Curcumin changes the polarity of tumor-associated microglia and eliminates glioblastoma

(2016) Sumit Mukherjee et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer Stem Cell Quiescence and Plasticity as Major Challenges in Cancer Therapy

(2016) Wanyin Chen et al.   Stem Cells International

Curcumin boosts DHA in the brain: Implications for the prevention of anxiety disorders

(2015) Aiguo Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

A novel stem cell culture model of recurrent glioblastoma

(2015) Maleeha A. Qazi et al.   JOURNAL OF NEURO-ONCOLOGY

Curcumin and Omega-3 Fatty Acids Enhance NK Cell-Induced Apoptosis of Pancreatic Cancer Cells but Curcumin Inhibits Interferon-γ Production: Benefits of Omega-3 with Curcumin against Cancer

(2015) Milan Fiala   MOLECULES

Inhibition of multidrug resistance protein 1 (MRP1) improves chemotherapy drug response in primary and recurrent glioblastoma multiforme

(2015) Amanda Tivnan et al.   Frontiers in Neuroscience

Exploiting the Immunomodulatory Properties of Chemotherapeutic Drugs to Improve the Success of Cancer Immunotherapy

(2015) Kelly Kersten et al.   Frontiers in Immunology

Immunosuppressive Myeloid Cells Induced by Chemotherapy Attenuate Antitumor CD4+ T-Cell Responses through the PD-1-PD-L1 Axis

(2014) Z.-C. Ding et al.   CANCER RESEARCH

Human NK Cells Kill Resting but Not Activated Microglia via NKG2D- and NKp46-Mediated Recognition

(2014) A. Lunemann et al.   JOURNAL OF IMMUNOLOGY

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

Effects of curcumin on ion channels and transporters

(2014) Xuemei Zhang et al.   Frontiers in Physiology

Monocyte chemoattractant protein-1 and the blood–brain barrier

(2013) Yao Yao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Coupling to a glioblastoma-directed antibody potentiates antitumor activity of curcumin

(2013) Phyllis Langone et al.   INTERNATIONAL JOURNAL OF CANCER

Lipid mediators of inflammation in obesity-related glomerulopathy

(2013) E. Nolan et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

Standards of care for treatment of recurrent glioblastoma—are we there yet?

(2012) Michael Weller et al.   NEURO-ONCOLOGY

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

Resolvin D1 and Its Precursor Docosahexaenoic Acid Promote Resolution of Adipose Tissue Inflammation by Eliciting Macrophage Polarization toward an M2-Like Phenotype

(2011) Esther Titos et al.   JOURNAL OF IMMUNOLOGY

Curcumin is a potent modulator of microglial gene expression and migration

(2011) Marcus Karlstetter et al.   Journal of Neuroinflammation

Synergistic Effect of Curcumin and Cisplatin via Down-Regulation of Thymidine Phosphorylase and Excision Repair Cross-Complementary 1 (ERCC1)

(2011) M.-S. Tsai et al.   MOLECULAR PHARMACOLOGY

Activating and inhibitory receptors of natural killer cells

(2010) Hollie J Pegram et al.   IMMUNOLOGY AND CELL BIOLOGY

Curcumin ameliorates oxaliplatin-induced chemoresistance in HCT116 colorectal cancer cells in vitro and in vivo

(2010) Lynne M. Howells et al.   INTERNATIONAL JOURNAL OF CANCER

The interaction of human natural killer cells with either unpolarized or polarized macrophages results in different functional outcomes

(2010) F. Bellora et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Curcumin blocks brain tumor formation

(2009) Sudarshana Purkayastha et al.   BRAIN RESEARCH

NK Cells Recognize and Kill Human Glioblastoma Cells with Stem Cell-Like Properties

(2009) R. Castriconi et al.   JOURNAL OF IMMUNOLOGY

Mechanisms of Chemoresistance to Alkylating Agents in Malignant Glioma

(2008) J. N. Sarkaria et al.   CLINICAL CANCER RESEARCH

Curcumin Inhibits the Activity of ABCG2/BCRP1, a Multidrug Resistance-Linked ABC Drug Transporter in Mice

(2008) Suneet Shukla et al.   PHARMACEUTICAL RESEARCH

Prostaglandins, bioassay and inflammation

(2006) R J Flower   BRITISH JOURNAL OF PHARMACOLOGY