Dual Actions of A2A and A3 Adenosine Receptor Ligand Prevents Obstruction-Induced Kidney Fibrosis in Mice

Dojuksan ameliorates tubulointerstitial fibrosis through irisin-mediated muscle-kidney crosstalk

(2020) Songling Jiang et al.   PHYTOMEDICINE

A novel combination of astilbin and low-dose methotrexate respectively targeting A 2A AR and its ligand adenosine for the treatment of collagen-induced arthritis

(2018) Yuxiang Ma et al.   BIOCHEMICAL PHARMACOLOGY

Early tyrosine phosphorylation events following adenosine A 2A receptor in human neutrophils: identification of regulated pathways

(2017) Miriam S. Giambelluca et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Adenosine contribution to normal renal physiology and chronic kidney disease

(2017) Carlos Oyarzún et al.   MOLECULAR ASPECTS OF MEDICINE

Renoprotective Effects of a Highly Selective A3 Adenosine Receptor Antagonist in a Mouse Model of Adriamycin-induced Nephropathy

(2016) Hye Sook Min et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Role of adenosine A2A receptor in cerebral ischemia reperfusion injury: Signaling to phosphorylated extracellular signal-regulated protein kinase (pERK1/2)

(2016) R.A. Mohamed et al.   NEUROSCIENCE

Reduced Adenosine Uptake and Its Contribution to Signaling that Mediates Profibrotic Activation in Renal Tubular Epithelial Cells: Implication in Diabetic Nephropathy

(2016) Catalina Kretschmar et al.   PLoS One

Adenosine A2a receptor stimulation prevents proteinuria in diabetic rats by promoting an anti-inflammatory phenotype without affecting oxidative stress

(2015) P. Persson et al.   Acta Physiologica

Increased adenosine levels contribute to ischemic kidney fibrosis in the unilateral ureteral obstruction model

(2015) JIN TANG et al.   Experimental and Therapeutic Medicine

Inflammatory processes in renal fibrosis

(2014) Xiao-Ming Meng et al.   Nature Reviews Nephrology

The Selective A 3 AR Antagonist LJ-1888 Ameliorates UUO-Induced Tubulointerstitial Fibrosis

(2013) Jiyoun Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Adenosine signaling during acute and chronic disease states

(2013) Harry Karmouty-Quintana et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Adenosine A2A Receptor: A Target for Regulating Renal Interstitial Fibrosis in Obstructive Nephropathy

(2013) Hang Xiao et al.   PLoS One

Structure–Activity Relationships of Truncated C2- or C8-Substituted Adenosine Derivatives as Dual Acting A2A and A3 Adenosine Receptor Ligands

(2011) Xiyan Hou et al.   JOURNAL OF MEDICINAL CHEMISTRY

A2B Adenosine Receptor-Mediated Induction of IL-6 Promotes CKD

(2011) Y. Dai et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Adenosine A2A receptor activation prevents progressive kidney fibrosis in a model of immune-associated chronic inflammation

(2011) Gabriela E. Garcia et al.   KIDNEY INTERNATIONAL

Cellular and molecular mechanisms of renal fibrosis

(2011) Youhua Liu   Nature Reviews Nephrology

A3Receptors Are Overexpressed in Pleura from Patients with Mesothelioma and Reduce Cell Growth via Akt/Nuclear Factor-κB Pathway

(2010) Katia Varani et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Adenosine: An Old Drug Newly Discovered

(2009) Holger K. Eltzschig   ANESTHESIOLOGY

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

Overview of factors contributing to the pathophysiology of progressive renal disease

(2008) Detlef O. Schlondorff   KIDNEY INTERNATIONAL

Activation of Adenosine 2A Receptors Preserves Structure and Function of Podocytes

(2007) A. S. Awad et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY