Memory B cells and plasma cells: The differentiative continuum of humoral immunity

The Transcription Factor T-bet Resolves Memory B Cell Subsets with Distinct Tissue Distributions and Antibody Specificities in Mice and Humans

(2020) John L. Johnson et al.   IMMUNITY

Differential Expression of IgM and IgD Discriminates Two Subpopulations of Human Circulating IgM+IgD+CD27+ B Cells That Differ Phenotypically, Functionally, and Genetically

(2020) Diana Bautista et al.   Frontiers in Immunology

Comprehensive analyses of B cell compartments across the human body reveal novel subsets and a gut resident memory phenotype

(2020) Nadine Marianne Weisel et al.   BLOOD

Memory CD73+IgM+ B cells protect against Plasmodium yoelii infection and express Granzyme B

(2020) Marcela Parra et al.   PLoS One

Extrafollicular responses in humans and SLE

(2019) Scott A. Jenks et al.   IMMUNOLOGICAL REVIEWS

T‐bet + memory B cells: Generation, function, and fate

(2019) James J. Knox et al.   IMMUNOLOGICAL REVIEWS

Memory B cell heterogeneity: Remembrance of things past

(2018) Gretchen Harms Pritchard et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Regulation of age-associated B cells by IRF5 in systemic autoimmunity

(2018) Michela Manni et al.   NATURE IMMUNOLOGY

IL-21 drives expansion and plasma cell differentiation of autoreactive CD11chiT-bet+ B cells in SLE

(2018) Shu Wang et al.   Nature Communications

The establishment of resident memory B cells in the lung requires local antigen encounter

(2018) S. Rameeza Allie et al.   NATURE IMMUNOLOGY

B cell alterations during BAFF inhibition with belimumab in SLE

(2018) Daniel Ramsköld et al.   EBioMedicine

B cells expressing the transcription factor T-bet drive lupus-like autoimmunity

(2017) Kira Rubtsova et al.   JOURNAL OF CLINICAL INVESTIGATION

Age-Associated B Cells Express a Diverse Repertoire of VHand Vκ Genes with Somatic Hypermutation

(2017) Lisa M. Russell Knode et al.   JOURNAL OF IMMUNOLOGY

Early derivation of IgM memory cells and bone marrow plasmablasts

(2017) Amber M. Papillion et al.   PLoS One

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites

(2017) Brahma V. Kumar et al.   Cell Reports

Malaria-induced interferon-γ drives the expansion of Tbethi atypical memory B cells

(2017) Nyamekye Obeng-Adjei et al.   PLoS Pathogens

A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells

(2016) Florian J. Weisel et al.   IMMUNITY

Somatically Hypermutated Plasmodium-Specific IgM+ Memory B Cells Are Rapid, Plastic, Early Responders upon Malaria Rechallenge

(2016) Akshay T. Krishnamurty et al.   IMMUNITY

Human Memory B Cells in Healthy Gingiva, Gingivitis, and Periodontitis

(2016) Rangsini Mahanonda et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: B Cell–Intrinsic T-bet Expression Is Required To Control Chronic Viral Infection

(2016) Burton E. Barnett et al.   JOURNAL OF IMMUNOLOGY

Hepatitis C viraemia reversibly maintains subset of antigen-specific T-bet+ tissue-like memory B cells

(2016) L.-Y. Chang et al.   JOURNAL OF VIRAL HEPATITIS

Human memory B cells

(2016) M Seifert et al.   LEUKEMIA

Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization

(2016) Mats Bemark et al.   Nature Communications

TLR7, IFNγ, and T-bet: Their roles in the development of ABCs in female-biased autoimmunity

(2015) Kira Rubtsova et al.   CELLULAR IMMUNOLOGY

Long-Lived Plasma Cells Are Contained within the CD19−CD38hiCD138+ Subset in Human Bone Marrow

(2015) Jessica L. Halliley et al.   IMMUNITY

Age-associated B cells: key mediators of both protective and autoreactive humoral responses

(2015) Martin S. Naradikian et al.   IMMUNOLOGICAL REVIEWS

Age-Associated B Cells: A T-bet–Dependent Effector with Roles in Protective and Pathogenic Immunity

(2015) Kira Rubtsova et al.   JOURNAL OF IMMUNOLOGY

Cellular Dynamics of Memory B Cell Populations: IgM+and IgG+Memory B Cells Persist Indefinitely as Quiescent Cells

(2015) Derek D. Jones et al.   JOURNAL OF IMMUNOLOGY

Functional capacities of human IgM memory B cells in early inflammatory responses and secondary germinal center reactions

(2015) Marc Seifert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expansion of Activated Peripheral Blood Memory B Cells in Rheumatoid Arthritis, Impact of B Cell Depletion Therapy, and Biomarkers of Response

(2015) Diana G. Adlowitz et al.   PLoS One

Spatial Map of Human T Cell Compartmentalization and Maintenance over Decades of Life

(2014) Joseph J.C. Thome et al.   CELL

Generation of memory B cells inside and outside germinal centers

(2014) Toshitada Takemori et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

Systematic Comparison of Gene Expression between Murine Memory and Naive B Cells Demonstrates That Memory B Cells Have Unique Signaling Capabilities

(2014) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

CD11c Expression Identifies a Population of Extrafollicular Antigen-Specific Splenic Plasmablasts Responsible for CD4 T-Independent Antibody Responses during Intracellular Bacterial Infection

(2014) R. Racine et al.   JOURNAL OF IMMUNOLOGY

Tissue Distribution and Dependence of Responsiveness of Human Antigen-Specific Memory B Cells

(2014) C. Giesecke et al.   JOURNAL OF IMMUNOLOGY

Lasting Antibody Responses Are Mediated by a Combination of Newly Formed and Established Bone Marrow Plasma Cells Drawn from Clonally Distinct Precursors

(2014) Irene Chernova et al.   JOURNAL OF IMMUNOLOGY

CD80 and PD-L2 define functionally distinct memory B cell subsets that are independent of antibody isotype

(2014) Griselda V Zuccarino-Catania et al.   NATURE IMMUNOLOGY

In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors*

(2013) Michelle Ratliff et al.   AGING CELL

T Cell-Dependent IgM Memory B Cells Generated during Bacterial Infection Are Required for IgG Responses to Antigen Challenge

(2013) J. L. Yates et al.   JOURNAL OF IMMUNOLOGY

T-box transcription factor T-bet, a key player in a unique type of B-cell activation essential for effective viral clearance

(2013) Kira Rubtsova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TLR7 drives accumulation of ABCs and autoantibody production in autoimmune-prone mice

(2012) Anatoly V. Rubtsov et al.   IMMUNOLOGIC RESEARCH

A germinal center–independent pathway generates unswitched memory B cells early in the primary response

(2012) Justin J. Taylor et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory B cells in the lung participate in protective humoral immune responses to pulmonary influenza virus reinfection

(2012) T. Onodera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A B-cell subset uniquely responsive to innate stimuli accumulates in aged mice

(2011) Y. Hao et al.   BLOOD

FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling

(2011) H. W. Sohn et al.   BLOOD

Toll-like receptor 7 (TLR7)-driven accumulation of a novel CD11c+ B-cell population is important for the development of autoimmunity

(2011) A. V. Rubtsov et al.   BLOOD

Attenuation of HIV-associated human B cell exhaustion by siRNA downregulation of inhibitory receptors

(2011) Lela Kardava et al.   JOURNAL OF CLINICAL INVESTIGATION

A Unique Role of the Cholera Toxin A1-DD Adjuvant for Long-Term Plasma and Memory B Cell Development

(2011) M. Bemark et al.   JOURNAL OF IMMUNOLOGY

Asymmetric B Cell Division in the Germinal Center Reaction

(2011) B. E. Barnett et al.   SCIENCE

Different B Cell Populations Mediate Early and Late Memory During an Endogenous Immune Response

(2011) K. A. Pape et al.   SCIENCE

Cutting Edge: Hierarchy of Maturity of Murine Memory B Cell Subsets

(2010) M. M. Tomayko et al.   JOURNAL OF IMMUNOLOGY

Coexistence of Quiescent and Active Adult Stem Cells in Mammals

(2010) L. Li et al.   SCIENCE

Atypical Memory B Cells Are Greatly Expanded in Individuals Living in a Malaria-Endemic Area

(2009) G. E. Weiss et al.   JOURNAL OF IMMUNOLOGY

Multiple layers of B cell memory with different effector functions

(2009) Ismail Dogan et al.   NATURE IMMUNOLOGY

Activated memory B cell subsets correlate with disease activity in systemic lupus erythematosus: Delineation by expression of CD27, IgD, and CD95

(2008) Annett M. Jacobi et al.   ARTHRITIS AND RHEUMATISM

The human spleen is a major reservoir for long-lived vaccinia virus-specific memory B cells

(2008) M. Mamani-Matsuda et al.   BLOOD

Human memory B cells: Memory B cells of a special kind

(2008) Ralf Küppers   IMMUNOLOGY AND CELL BIOLOGY

Discriminating gene expression profiles of memory B cell subpopulations

(2008) Götz R.A. Ehrhardt et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Evidence for HIV-associated B cell exhaustion in a dysfunctional memory B cell compartment in HIV-infected viremic individuals

(2008) Susan Moir et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Broad dispersion and lung localization of virus-specific memory B cells induced by influenza pneumonia

(2008) H. M. Joo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BLyS inhibition eliminates primary B cells but leaves natural and acquired humoral immunity intact

(2008) J. L. Scholz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA