Reprogramming of DNA methylation is linked to successful human preimplantation development

5-Formylcytosine landscapes of human preimplantation embryos at single-cell resolution

(2020) Yun Gao et al.   PLOS BIOLOGY

The methylome of a human polar body reflects that of its sibling oocyte and its aberrance may indicate poor embryo development

(2020) Peng Yuan et al.   HUMAN REPRODUCTION

Resetting histone modifications during human parental-to-zygotic transition

(2019) Weikun Xia et al.   SCIENCE

Sperm DNA Methylation Epimutation Biomarkers for Male Infertility and FSH Therapeutic Responsiveness

(2019) Saturnino Luján et al.   Scientific Reports

High-glucose concentrations change DNA methylation levels in human IVM oocytes

(2018) Qian Wang et al.   HUMAN REPRODUCTION

Dynamics of the epigenetic landscape during the maternal-to-zygotic transition

(2018) Melanie A. Eckersley-Maslin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Genomic insights into chromatin reprogramming to totipotency in embryos

(2018) Sabrina Ladstätter et al.   JOURNAL OF CELL BIOLOGY

Single-cell DNA methylome sequencing of human preimplantation embryos

(2017) Ping Zhu et al.   NATURE GENETICS

Similar kinetics for 5-methylcytosine and 5-hydroxymethylcytosine during human preimplantation development in vitro

(2016) Laetitia Petrussa et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

TET-mediated DNA demethylation controls gastrulation by regulating Lefty–Nodal signalling

(2016) Hai-Qiang Dai et al.   NATURE

De novo DNA methylation drives 5hmC accumulation in mouse zygotes

(2016) Rachel Amouroux et al.   NATURE CELL BIOLOGY

DNA methylation dynamics in mouse preimplantation embryos revealed by mass spectrometry

(2016) Yoshinori Okamoto et al.   Scientific Reports

Different Levels of DNA Methylation Detected in Human Sperms after Morphological Selection Using High Magnification Microscopy

(2016) Nino Guy Cassuto et al.   Biomed Research International

Simultaneous deletion of the methylcytosine oxidases Tet1 and Tet3 increases transcriptome variability in early embryogenesis

(2015) Jinsuk Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective impairment of methylation maintenance is the major cause of DNA methylation reprogramming in the early embryo

(2015) Julia Arand et al.   Epigenetics & Chromatin

Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis

(2015) Maria Vera-Rodriguez et al.   Nature Communications

TET-catalyzed 5-methylcytosine hydroxylation is dynamically regulated by metabolites

(2014) Hui Yang et al.   CELL RESEARCH

Active and Passive Demethylation of Male and Female Pronuclear DNA in the Mammalian Zygote

(2014) Fan Guo et al.   Cell Stem Cell

DNA methylation dynamics during epigenetic reprogramming in the germline and preimplantation embryos

(2014) D. M. Messerschmidt et al.   GENES & DEVELOPMENT

DNA methylation dynamics of the human preimplantation embryo

(2014) Zachary D. Smith et al.   NATURE

The DNA methylation landscape of human early embryos

(2014) Hongshan Guo et al.   NATURE

Human pre-implantation embryo development

(2012) K. K. Niakan et al.   DEVELOPMENT

Dynamic blastomere behaviour reflects human embryo ploidy by the four-cell stage

(2012) Shawn L. Chavez et al.   Nature Communications

Lineage-specific distribution of high levels of genomic

(2011) Alexey Ruzov et al.   CELL RESEARCH

Generation and replication-dependent dilution of 5fC and 5caC during mouse preimplantation development

(2011) Azusa Inoue et al.   CELL RESEARCH

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Replication-Dependent Loss of 5-Hydroxymethylcytosine in Mouse Preimplantation Embryos

(2011) A. Inoue et al.   SCIENCE

5-Hydroxymethylcytosine in the mammalian zygote is linked with epigenetic reprogramming

(2011) Mark Wossidlo et al.   Nature Communications

Dynamic link of DNA demethylation, DNA strand breaks and repair in mouse zygotes

(2010) Mark Wossidlo et al.   EMBO JOURNAL

Non-invasive imaging of human embryos before embryonic genome activation predicts development to the blastocyst stage

(2010) Connie C Wong et al.   NATURE BIOTECHNOLOGY

Chromosome instability is common in human cleavage-stage embryos

(2009) Evelyne Vanneste et al.   NATURE MEDICINE