Altered faecal microbiome and metabolome in IgG4-related sclerosing cholangitis and primary sclerosing cholangitis

Dysbiosis-Induced Secondary Bile Acid Deficiency Promotes Intestinal Inflammation

(2020) Sidhartha R. Sinha et al.   Cell Host & Microbe

Development of the Microbiota and Associations With Birth Mode, Diet, and Atopic Disorders in a Longitudinal Analysis of Stool Samples, Collected From Infancy Through Early Childhood

(2020) Gianluca Galazzo et al.   GASTROENTEROLOGY

Targeting the Gut Microbiome as a Treatment for Primary Sclerosing Cholangitis

(2020) Ayesha Shah et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Cytokine-like Roles for Metabolites in Immunity

(2020) Zbigniew Zasłona et al.   MOLECULAR CELL

The long-term outcomes of patients with immunoglobulin G4-related sclerosing cholangitis: the Mayo Clinic experience

(2020) Ahmad Hassan Ali et al.   JOURNAL OF GASTROENTEROLOGY

Advances in the diagnosis and management of IgG4 related disease

(2020) Marco Lanzillotta et al.   BMJ-British Medical Journal

Gut microbial metabolites as multi-kingdom intermediates

(2020) Kimberly A. Krautkramer et al.   NATURE REVIEWS MICROBIOLOGY

Gut microbiota in human metabolic health and disease

(2020) Yong Fan et al.   NATURE REVIEWS MICROBIOLOGY

IgG4-related disease: an update on pathophysiology and implications for clinical care

(2020) Cory A. Perugino et al.   Nature Reviews Rheumatology

Altered gut microbial metabolism of essential nutrients in primary sclerosing cholangitis

(2020) Martin Kummen et al.   GASTROENTEROLOGY

Accumulation of distinct persistent organic pollutants is associated with adipose tissue inflammation

(2020) Ulrike Rolle-Kampczyk et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis

(2019) Nobuhiro Nakamoto et al.   Nature Microbiology

The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes

(2019) Maik Luu et al.   Nature Communications

Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis

(2019) Sara Lemoinne et al.   GUT

Multi-omics of the gut microbial ecosystem in inflammatory bowel diseases

(2019) Jason Lloyd-Price et al.   NATURE

Consistent alterations in faecal microbiomes of patients with primary sclerosing cholangitis independent of associated colitis

(2019) Malte Rühlemann et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Alterations of gut microbiome in autoimmune hepatitis

(2019) Yiran Wei et al.   GUT

Quantitative microbiome profiling disentangles inflammation- and bile duct obstruction-associated microbiota alterations across PSC/IBD diagnoses

(2019) Sara Vieira-Silva et al.   Nature Microbiology

Fatty Acid Metabolites Combine with Reduced β Oxidation to Activate Th17 Inflammation in Human Type 2 Diabetes

(2019) Dequina A. Nicholas et al.   Cell Metabolism

The protective effect of lithocholic acid on the intestinal epithelial barrier is mediated by the vitamin D receptor via a SIRT1/Nrf2 and NF-κB dependent mechanism in Caco-2 cells

(2019) Baiyu Yao et al.   TOXICOLOGY LETTERS

Interplay between the human gut microbiome and host metabolism

(2019) Alessia Visconti et al.   Nature Communications

Detection of Succinate by Intestinal Tuft Cells Triggers a Type 2 Innate Immune Circuit

(2018) Marija S. Nadjsombati et al.   IMMUNITY

Primary sclerosing cholangitis

(2018) Jessica K Dyson et al.   LANCET

The fecal metabolome as a functional readout of the gut microbiome

(2018) Jonas Zierer et al.   NATURE GENETICS

Activation of intestinal tuft cell-expressed Sucnr1 triggers type 2 immunity in the mouse small intestine

(2018) Weiwei Lei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of GABAA Receptors in Colon Epithelium Exacerbates Acute Colitis

(2018) Xuelian Ma et al.   Frontiers in Immunology

Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease

(2018) Huikuan Chu et al.   GUT

IgG4-Related Sclerosing Cholangitis and Primary Sclerosing Cholangitis

(2018) Atsushi Tanaka   Gut and Liver

Metabolomic Profiling of Portal Blood and Bile Reveals Metabolic Signatures of Primary Sclerosing Cholangitis

(2018) Pamela Tietz-Bogert et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A computational framework to integrate high-throughput ‘-omics’ datasets for the identification of potential mechanistic links

(2018) Helle Krogh Pedersen et al.   Nature Protocols

The Role of Succinate in the Regulation of Intestinal Inflammation

(2018) Jessica Connors et al.   Nutrients

Synergistic Effect of Quinic Acid Derived From Syzygium cumini and Undecanoic Acid Against Candida spp. Biofilm and Virulence

(2018) Subramanian Muthamil et al.   Frontiers in Microbiology

Sphingolipids and their metabolism in physiology and disease

(2017) Yusuf A. Hannun et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Distinct gut microbiota profiles in patients with primary sclerosing cholangitis and ulcerative colitis

(2017) Lukas Bajer et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Primary sclerosing cholangitis is characterised by intestinal dysbiosis independent from IBD

(2016) João Sabino et al.   GUT

The gut microbial profile in patients with primary sclerosing cholangitis is distinct from patients with ulcerative colitis without biliary disease and healthy controls

(2016) Martin Kummen et al.   GUT

2-Hydroxyisocaproic acid is bactericidal in human dental root canalsex vivo

(2016) M. Sakko et al.   INTERNATIONAL ENDODONTIC JOURNAL

IgG4-related hepatobiliary disease: an overview

(2016) Emma L. Culver et al.   Nature Reviews Gastroenterology & Hepatology

Immunological GABAergic interactions and therapeutic applications in autoimmune diseases

(2015) Gérald J. Prud'homme et al.   AUTOIMMUNITY REVIEWS

Characterization of Intestinal Microbiota in Ulcerative Colitis Patients with and without Primary Sclerosing Cholangitis

(2015) D. Kevans et al.   Journal of Crohns & Colitis

The microbiota regulates type 2 immunity through ROR t+ T cells

(2015) C. Ohnmacht et al.   SCIENCE

Acylcarnitines activate proinflammatory signaling pathways

(2014) Jennifer M. Rutkowsky et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Alterations of the human gut microbiome in liver cirrhosis

(2014) Nan Qin et al.   NATURE

Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel

(2013) Alvin B. Coda et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

Metabolomic profiling of 17 bile acids in serum from patients with primary biliary cirrhosis and primary sclerosing cholangitis: A pilot study

(2011) Jocelyn Trottier et al.   DIGESTIVE AND LIVER DISEASE

Diagnosis and management of primary sclerosing cholangitis

(2009) Roger Chapman et al.   HEPATOLOGY