Gut inflammation exacerbates high-fat diet induced steatosis by suppressing VLDL-TG secretion through HNF4α pathway

Downregulation of OCTN2 by cytokines plays an important role in the progression of inflammatory bowel disease

(2020) Ping Li et al.   BIOCHEMICAL PHARMACOLOGY

Intestinally derived bacterial products stimulate development of nonalcoholic steatohepatitis

(2019) Waleska Dornas et al.   PHARMACOLOGICAL RESEARCH

Systematic Review With Meta-analysis: Epidemiology of Nonalcoholic Fatty Liver Disease in Patients With Inflammatory Bowel Disease

(2019) Zi-Yuan Zou et al.   INFLAMMATORY BOWEL DISEASES

Onset of Ulcerative Colitis in a Patient with Nonalcoholic Fatty Liver Disease (NAFLD): Dramatic Effect of Plant-based Diet for NAFLD

(2019) Mitsuro Chiba et al.   INFLAMMATORY BOWEL DISEASES

The regulation of hepatic fatty acid synthesis and partitioning: the effect of nutritional state

(2019) Leanne Hodson et al.   Nature Reviews Endocrinology

Up-regulation of hepatic fatty acid transporters and inhibition/down-regulation of hepatic OCTN2 contribute to olanzapine-induced liver steatosis

(2019) Ting Jiang et al.   TOXICOLOGY LETTERS

High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage

(2019) Shohei Tanaka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Recent Insights into the Pathogenesis of Nonalcoholic Fatty Liver Disease

(2018) Juan Pablo Arab et al.   Annual Review of Pathology-Mechanisms of Disease

Expression and regulation of proton-coupled oligopeptide transporters in colonic tissue and immune cells of mice

(2018) Yuqing Wang et al.   BIOCHEMICAL PHARMACOLOGY

High fat diet-induced oxidative stress blocks hepatocyte nuclear factor 4α and leads to hepatic steatosis in mice

(2018) Dongsheng Yu et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Non-alcoholic fatty liver disease phenotypes in patients with inflammatory bowel disease

(2018) Alessandro Sartini et al.   Cell Death & Disease

Gut inflammation exacerbates hepatic injury in the high-fat diet induced NAFLD mouse: Attention to the gut-vascular barrier dysfunction

(2018) Chunwei Cheng et al.   LIFE SCIENCES

Molecular pathways of nonalcoholic fatty liver disease development and progression

(2018) Fernando Bessone et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The role of macrophages in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis

(2018) Konstantin Kazankov et al.   Nature Reviews Gastroenterology & Hepatology

Clozapine-induced reduction of l-carnitine reabsorption via inhibition/down-regulation of renal carnitine/organic cation transporter 2 contributes to liver lipid metabolic disorder in mice

(2018) Wei Wang et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Current and emerging therapeutic targets for IBD

(2017) Markus F. Neurath   Nature Reviews Gastroenterology & Hepatology

Global burden of NAFLD and NASH: trends, predictions, risk factors and prevention

(2017) Zobair Younossi et al.   Nature Reviews Gastroenterology & Hepatology

Loss of Junctional Adhesion Molecule A Promotes Severe Steatohepatitis in Mice on a Diet High in Saturated Fat, Fructose, and Cholesterol

(2016) Khalidur Rahman et al.   GASTROENTEROLOGY

Hyperhomocysteinemia activates the aryl hydrocarbon receptor/CD36 pathway to promote hepatic steatosis in mice

(2016) Liu Yao et al.   HEPATOLOGY

Incidence and Predictors of Nonalcoholic Fatty Liver Disease by Serum Biomarkers in Patients with Inflammatory Bowel Disease

(2016) Talat Bessissow et al.   INFLAMMATORY BOWEL DISEASES

High fat diet exacerbates dextran sulfate sodium induced colitis through disturbing mucosal dendritic cell homeostasis

(2016) Lu Cheng et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Chronic inflammation aggravates metabolic disorders of hepatic fatty acids in high-fat diet-induced obese mice

(2015) Lei Zhao et al.   Scientific Reports

Hepatic mitochondrial and ER stress induced by defective PPARα signaling in the pathogenesis of hepatic steatosis

(2014) Qiaozhu Su et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

High-Fat Diet-Induced Obesity Exacerbates Inflammatory Bowel Disease in Genetically Susceptible Mdr1a−/− Male Mice

(2013) Jisun Paik et al.   JOURNAL OF NUTRITION

NR2F1 disrupts synergistic activation of theMTTPgene transcription by HNF-4α and HNF-1α

(2012) Kezhi Dai et al.   JOURNAL OF LIPID RESEARCH

L-Carnitine - Metabolic Functions and Meaning in Humans Life

(2011) Jolanta Pekala et al.   CURRENT DRUG METABOLISM

DSS induced colitis increases portal LPS levels and enhances hepatic inflammation and fibrogenesis in experimental NASH

(2011) Erwin Gäbele et al.   JOURNAL OF HEPATOLOGY

Hepatic Hepatocyte Nuclear Factor 4α Is Essential for Maintaining Triglyceride and Cholesterol Homeostasis

(2010) Liya Yin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Hepatocyte nuclear factor-4 alpha regulates liver triglyceride metabolism in part through secreted phospholipase A2 GXIIB

(2010) Min Guan et al.   HEPATOLOGY

Elevated endotoxin levels in non-alcoholic fatty liver disease

(2010) Alison L Harte et al.   Journal of Inflammation-London

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Modulation of hepatocyte nuclear factor-4α function by the peroxisome-proliferator-activated receptor-γ co-activator-1α in the acute-phase response

(2008) Zhongyan Wang et al.   BIOCHEMICAL JOURNAL