Interpreting NUMTs in forensic genetics: Seeing the forest for the trees

A Continuous Statistical Phasing Framework for the Analysis of Forensic Mitochondrial DNA Mixtures

(2021) Utpal Smart et al.   Genes

Massive parallel sequencing in forensics: advantages, issues, technicalities, and prospects

(2020) David Ballard et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Characterization of background noise in MiSeq MPS data when sequencing human mitochondrial DNA from various sample sources and library preparation methods

(2020) Jennifer A. McElhoe et al.   MITOCHONDRION

Numt identification and removal with RtN!

(2020) August E Woerner et al.   BIOINFORMATICS

Damage patterns observed in mtDNA control region MPS data for a range of template concentrations and when using different amplification approaches

(2020) Charity A. Holland et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Evidence for multi-copy Mega-NUMTs in the human genome

(2020) Sabine Lutz-Bonengel et al.   NUCLEIC ACIDS RESEARCH

Reducing the Number of Mismatches between Hairs and Buccal References When Analysing mtDNA Heteroplasmic Variation by Massively Parallel Sequencing

(2020) Kristiaan J. van der Gaag et al.   Genes

No further evidence for paternal leakage of mitochondrial DNA in humans yet

(2019) Sabine Lutz-Bonengel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Germline selection shapes human mitochondrial DNA diversity

(2019) Wei Wei et al.   SCIENCE

Quasi-Mendelian paternal inheritance of mitochondrial DNA: A notorious artifact, or anticipated behavior?

(2019) Sofia Annis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Nuclear mtDNA Concatemer (Mega-NUMT) Could Mimic Paternal Inheritance of Mitochondrial Genome

(2019) Jorune Balciuniene et al.   Frontiers in Genetics

SD quants—Sensitive detection tetraplex-system for nuclear and mitochondrial DNA quantification and degradation inference

(2019) Catarina Xavier et al.   Forensic Science International-Genetics

NUMT Confounding Biases Mitochondrial Heteroplasmy Calls in Favor of the Reference Allele

(2019) Hannah Maude et al.   Frontiers in Cell and Developmental Biology

A novel phylogenetic approach for de novo discovery of putative nuclear mitochondrial (pNumt) haplotypes

(2019) Utpal Smart et al.   Forensic Science International-Genetics

Report from the STRAND Working Group on the 2019 STR sequence nomenclature meeting

(2019) Katherine Butler Gettings et al.   Forensic Science International-Genetics

Impact of the sequencing method on the detection and interpretation of mitochondrial DNA length heteroplasmy

(2019) Kimberly Sturk-Andreaggi et al.   Forensic Science International-Genetics

Sensitivity of mitochondrial DNA heteroplasmy detection using Next Generation Sequencing

(2019) María del Mar González et al.   MITOCHONDRION

Assessing heteroplasmic variant drift in the mtDNA control region of human hairs using an MPS approach

(2018) Jamie M. Gallimore et al.   Forensic Science International-Genetics

Developmental validation of a Nextera XT mitogenome Illumina MiSeq sequencing method for high-quality samples

(2018) Michelle A. Peck et al.   Forensic Science International-Genetics

Repair of DNA damage caused by cytosine deamination in mitochondrial DNA of forensic case samples

(2018) Erin M. Gorden et al.   Forensic Science International-Genetics

Evaluation of the Precision ID mtDNA Whole Genome Panel on two massively parallel sequencing systems

(2018) August E. Woerner et al.   Forensic Science International-Genetics

Evaluation of the precision ID whole MtDNA genome panel for forensic analyses

(2018) Christina Strobl et al.   Forensic Science International-Genetics

Massively parallel sequencing-enabled mixture analysis of mitochondrial DNA samples

(2018) Jennifer D. Churchill et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Applications of Probe Capture Enrichment Next Generation Sequencing for Whole Mitochondrial Genome and 426 Nuclear SNPs for Forensically Challenging Samples

(2018) Shelly Shih et al.   Genes

Bioinformatic removal of NUMT-associated variants in mitotiling next-generation sequencing data from whole blood samples

(2018) Joseph David Ring et al.   ELECTROPHORESIS

Assessing mitochondrial heteroplasmy using next generation sequencing: A note of caution

(2018) Mauro Santibanez-Koref et al.   MITOCHONDRION

Development of a triplex Mtdna Qpcr assay to assess quantification, degradation, inhibition, and amplification target copy numbers

(2018) Mark F. Kavlick   MITOCHONDRION

Biparental Inheritance of Mitochondrial DNA in Humans

(2018) Shiyu Luo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fragmented Nuclear DNA is the Predominant Genetic Material in Human Hair Shafts

(2018) Michael D. Brandhagen et al.   Genes

Recovery of mtDNA from unfired metallic ammunition components with an assessment of sequence profile quality and DNA damage through MPS analysis

(2018) Mitchell M. Holland et al.   Forensic Science International-Genetics

Performance evaluation of a mitogenome capture and Illumina sequencing protocol using non-probative, case-type skeletal samples: Implications for the use of a positive control in a next-generation sequencing procedure

(2017) Charla Marshall et al.   Forensic Science International-Genetics

Considering DNA damage when interpreting mtDNA heteroplasmy in deep sequencing data

(2017) Molly M. Rathbun et al.   Forensic Science International-Genetics

A phylogenetic approach for haplotype analysis of sequence data from complex mitochondrial mixtures

(2017) Samuel H. Vohr et al.   Forensic Science International-Genetics

MPS analysis of the mtDNA hypervariable regions on the MiSeq with improved enrichment

(2017) Mitchell M. Holland et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Optimized mtDNA Control Region Primer Extension Capture Analysis for Forensically Relevant Samples and Highly Compromised mtDNA of Different Age and Origin

(2017) Mayra Eduardoff et al.   Genes

NumtS colonization in mammalian genomes

(2017) F. M. Calabrese et al.   Scientific Reports

Massively parallel sequencing of forensic STRs: Considerations of the DNA commission of the International Society for Forensic Genetics (ISFG) on minimal nomenclature requirements

(2016) Walther Parson et al.   Forensic Science International-Genetics

Age-Related and Heteroplasmy-Related Variation in Human mtDNA Copy Number

(2016) Manja Wachsmuth et al.   PLoS Genetics

Analysis of mixtures using next generation sequencing of mitochondrial DNA hypervariable regions

(2015) Hanna Kim et al.   CROATIAN MEDICAL JOURNAL

Mitochondrial DNA heteroplasmy in the emerging field of massively parallel sequencing

(2015) Rebecca S. Just et al.   Forensic Science International-Genetics

Massively parallel sequencing of complete mitochondrial genomes from hair shaft samples

(2015) Walther Parson et al.   Forensic Science International-Genetics

Full mtGenome reference data: Development and characterization of 588 forensic-quality haplotypes representing three U.S. populations

(2015) Rebecca S. Just et al.   Forensic Science International-Genetics

Next generation sequencing and its applications in forensic genetics

(2015) Claus Børsting et al.   Forensic Science International-Genetics

Simultaneous Whole Mitochondrial Genome Sequencing with Short Overlapping Amplicons Suitable for Degraded DNA Using the Ion Torrent Personal Genome Machine

(2015) Lakshmi Chaitanya et al.   HUMAN MUTATION

DNA Commission of the International Society for Forensic Genetics: Revised and extended guidelines for mitochondrial DNA typing

(2014) W. Parson et al.   Forensic Science International-Genetics

High-quality and high-throughput massively parallel sequencing of the human mitochondrial genome using the Illumina MiSeq

(2014) Jonathan L. King et al.   Forensic Science International-Genetics

Development and assessment of an optimized next-generation DNA sequencing approach for the mtgenome using the Illumina MiSeq

(2014) Jennifer A. McElhoe et al.   Forensic Science International-Genetics

Simultaneous Detection of Human Mitochondrial DNA and Nuclear-Inserted Mitochondrial-origin Sequences (NumtS) using Forensic mtDNA Amplification Strategies and Pyrosequencing Technology

(2014) Brittania J. Bintz et al.   JOURNAL OF FORENSIC SCIENCES

High-throughput sequencing in mitochondrial DNA research

(2014) Fei Ye et al.   MITOCHONDRION

The genomic landscape of polymorphic human nuclear mitochondrial insertions

(2014) Gargi Dayama et al.   NUCLEIC ACIDS RESEARCH

Maternal age effect and severe germ-line bottleneck in the inheritance of human mitochondrial DNA

(2014) B. Rebolledo-Jaramillo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of the remains of King Richard III

(2014) Turi E. King et al.   Nature Communications

Evaluation of next generation mtGenome sequencing using the Ion Torrent Personal Genome Machine (PGM)

(2013) Walther Parson et al.   Forensic Science International-Genetics

Selective Enrichment and Sequencing of Whole Mitochondrial Genomes in the Presence of Nuclear Encoded Mitochondrial Pseudogenes (Numts)

(2012) Jonci N. Wolff et al.   PLoS One

Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes

(2010) Mingkun Li et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Preventing the pollution of mitochondrial datasets with nuclear mitochondrial paralogs (numts)

(2010) Sébastien Calvignac et al.   MITOCHONDRION

Molecular Poltergeists: Mitochondrial DNA Copies (numts) in Sequenced Nuclear Genomes

(2010) Einat Hazkani-Covo et al.   PLoS Genetics

A Comparative Approach Shows Differences in Patterns of Numt Insertion During Hominoid Evolution

(2009) M. I. Jensen-Seaman et al.   JOURNAL OF MOLECULAR EVOLUTION

Investigation of Heteroplasmy in the Human Mitochondrial DNA Control Region: A Synthesis of Observations from More Than 5000 Global Population Samples

(2009) Jodi A. Irwin et al.   JOURNAL OF MOLECULAR EVOLUTION

DNA extraction procedures meaningfully influence qPCR-based mtDNA copy number determination

(2009) Wen Guo et al.   MITOCHONDRION

‘Mitominis’: multiplex PCR analysis of reduced size amplicons for compound sequence analysis of the entire mtDNA control region in highly degraded samples

(2008) Cordula Eichmann et al.   INTERNATIONAL JOURNAL OF LEGAL MEDICINE

Postmortem Miscoding Lesions in Sequence Analysis of Human Ancient Mitochondrial DNA

(2008) Ryan Lamers et al.   JOURNAL OF MOLECULAR EVOLUTION