Journal
FOOD CHEMISTRY
Volume 351, Issue -, Pages -Publisher
ELSEVIER SCI LTD
DOI: 10.1016/j.foodchem.2021.129279
Keywords
Enrofloxacin (ENR); Lyophilized egg; Egg white; Egg yolk; Consumer exposure assessment
Funding
- Universidad Nacional de San Luis [PROICO 2-1816]
- Universidad Nacional del Litoral [CAI + D 2016-50120150100110LI]
- CONICET (Consejo Nacional de Investigaciones Cientificas y Tecnicas) [0605, 0111]
- ANPCyT (Agencia Nacional de Promocion Cientifica y Tecnologica) [PICT 2016-1776, 2017-0340]
- CONICET
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The study found that long-term administration of enrofloxacin to laying hens resulted in high concentrations of enrofloxacin in egg white, and consumer exposure assessment showed potential toxicological levels.
The use of the antibiotic enrofloxacin (ENR) in poultry is controversial. A high-performance liquid chromatography coupled to fast-scanning fluorescence detection (HPLC FSFD) method for the determination of ENR in egg white, egg yolk, and lyophilized samples was developed. In a first analysis, the long-term administration of ENR (100 days) to laying hens was carried out to determine its presence in egg white, yolk, or both. The predominance of ENR was observed in egg white and variations in the weight of egg white and eggshell was evidenced, showing a potential problem in the industry. Eventually, the presence of ENR was confirmed in commercial lyophilized egg white samples in concentration values around 350 mu g kg(-1). The consumer exposure assessment was estimated for children, adolescents, and adults. The result displayed that, in an intake of lyophilized egg white with food-producing animals, the %ADI exceeds 100%, showing toxicological levels.
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