Maresin 1 activates LGR6 signaling to inhibit smooth muscle cell activation and attenuate murine abdominal aortic aneurysm formation

Maresin 1 activates LGR6 receptor promoting phagocyte immunoresolvent functions

(2019) Nan Chiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Novel Role of IL (Interleukin)-1β in Neutrophil Extracellular Trap Formation and Abdominal Aortic AneurysmsHighlights

(2018) Akshaya K. Meher et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Proefferocytic Therapy Promotes Transforming Growth Factor-β Signaling and Prevents Aneurysm Formation

(2018) Yoko Kojima et al.   CIRCULATION

Resolvin D1 decreases abdominal aortic aneurysm formation by inhibiting NETosis in a mouse model

(2018) Michael Spinosa et al.   JOURNAL OF VASCULAR SURGERY

A novel swine model of abdominal aortic aneurysm

(2018) J. Michael Cullen et al.   JOURNAL OF VASCULAR SURGERY

Maresin 1 Promotes Inflammatory Resolution, Neuroprotection, and Functional Neurological Recovery After Spinal Cord Injury

(2017) Isaac Francos-Quijorna et al.   JOURNAL OF NEUROSCIENCE

Discovery of specialized pro-resolving mediators marks the dawn of resolution physiology and pharmacology

(2017) Charles N. Serhan   MOLECULAR ASPECTS OF MEDICINE

Maresin 1 Ameliorates Lung Ischemia/Reperfusion Injury by Suppressing Oxidative Stress via Activation of the Nrf-2-Mediated HO-1 Signaling Pathway

(2017) Quanchao Sun et al.   Oxidative Medicine and Cellular Longevity

D-series resolvins inhibit murine abdominal aortic aneurysm formation and increase M2 macrophage polarization

(2016) Nicolas H. Pope et al.   FASEB JOURNAL

Smooth muscle cell-specific Tgfbr1 deficiency promotes aortic aneurysm formation by stimulating multiple signaling events

(2016) Pu Yang et al.   Scientific Reports

Inflammatory Cell Phenotypes in AAAsSignificance

(2015) Matthew A. Dale et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Systemic delivery of proresolving lipid mediators resolvin D2 and maresin 1 attenuates intimal hyperplasia in mice

(2015) Daisuke Akagi et al.   FASEB JOURNAL

Phagocytosis of apoptotic cells in homeostasis

(2015) Sanja Arandjelovic et al.   NATURE IMMUNOLOGY

Maresin 1 mitigates LPS-induced acute lung injury in mice

(2014) Jie Gong et al.   BRITISH JOURNAL OF PHARMACOLOGY

Tgfbr2 disruption in postnatal smooth muscle impairs aortic wall homeostasis

(2014) Wei Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Pro-resolving lipid mediators are leads for resolution physiology

(2014) Charles N. Serhan   NATURE

ALX/FPR2 receptor for RvD1 is expressed and functional in salivary glands

(2013) Joel W. Nelson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Angiotensin II–dependent TGF-β signaling contributes to Loeys-Dietz syndrome vascular pathogenesis

(2013) Elena M. Gallo et al.   JOURNAL OF CLINICAL INVESTIGATION

Maresin 1, a Proresolving Lipid Mediator Derived from Omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis

(2013) R. Marcon et al.   JOURNAL OF IMMUNOLOGY

Resolvin D1 Receptor Stereoselectivity and Regulation of Inflammation and Proresolving MicroRNAs

(2012) Sriram Krishnamoorthy et al.   AMERICAN JOURNAL OF PATHOLOGY

Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening

(2012) S. G. Thompson et al.   BRITISH JOURNAL OF SURGERY

Novel Anti-Inflammatory-Pro-Resolving Mediators and Their Receptors

(2012) Charles N. Serhan et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain

(2012) Charles N. Serhan et al.   FASEB JOURNAL

Differential gender- and species-specific formation of aneurysms using a novel method of inducing abdominal aortic aneurysms

(2012) Adriana Laser et al.   JOURNAL OF SURGICAL RESEARCH

Loss-of-function mutations in TGFB2 cause a syndromic presentation of thoracic aortic aneurysm

(2012) Mark E Lindsay et al.   NATURE GENETICS

Development of a novel murine model of aortic aneurysms using peri-adventitial elastase

(2012) Castigliano M. Bhamidipati et al.   SURGERY

TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice

(2010) Yu Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Resolvin D1 binds human phagocytes with evidence for proresolving receptors

(2010) S. Krishnamoorthy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions

(2008) Charles N. Serhan et al.   JOURNAL OF EXPERIMENTAL MEDICINE