Young plasma administration mitigates depression‐like behaviours in chronic mild stress‐exposed aged rats by attenuating apoptosis in prefrontal cortex

Young plasma ameliorates aging-related acute brain injury after intracerebral hemorrhage

(2019) Jun-Jie Yuan et al.   BIOSCIENCE REPORTS

Plasma-Based Strategies for Therapeutic Modulation of Brain Aging

(2019) Viktoria Kheifets et al.   Neurotherapeutics

The effects of sub-anesthetic ketamine plus ethanol on behaviors and apoptosis in the prefrontal cortex and hippocampus of adolescent rats

(2019) Qing Li et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Extracellular vesicles extracted from young donor serum attenuate inflammaging via partially rejuvenating aged T-cell immunotolerance

(2018) Weikan Wang et al.   FASEB JOURNAL

Neuronal Cell Death

(2018) Michael Fricker et al.   PHYSIOLOGICAL REVIEWS

Reduced Synapse and Axon Numbers in the Prefrontal Cortex of Rats Subjected to a Chronic Stress Model for Depression

(2018) Dávid Csabai et al.   Frontiers in Cellular Neuroscience

Making sense of rodent models of anhedonia

(2018) Simona Scheggi et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neuronal Cell Death Mechanisms in Major Neurodegenerative Diseases

(2018) Hao Chi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Changes in brain metabolites related to stress resilience: Metabolomic analysis of the hippocampus in a rat model of depression

(2018) Hayato Akimoto et al.   BEHAVIOURAL BRAIN RESEARCH

Intranasal Cerebrolysin Attenuates Learning and Memory Impairments in D-galactose-Induced Senescence in Mice

(2017) Ehsan Pourmemar et al.   EXPERIMENTAL GERONTOLOGY

Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis

(2017) Zhan Zhao et al.   Frontiers in Molecular Neuroscience

Intervention Research in Late-Life Depression: Challenges and Opportunities

(2016) Helen Lavretsky   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

A single heterochronic blood exchange reveals rapid inhibition of multiple tissues by old blood

(2016) Justin Rebo et al.   Nature Communications

In vivo assessment of behavioral recovery and circulatory exchange in the peritoneal parabiosis model

(2016) Joseph M. Castellano et al.   Scientific Reports

Preclinical Assessment of Young Blood Plasma for Alzheimer Disease

(2016) Jinte Middeldorp et al.   JAMA Neurology

Dendritic Spines in Depression: What We Learned from Animal Models

(2016) Hui Qiao et al.   NEURAL PLASTICITY

Blood-Borne Revitalization of the Aged Brain

(2015) Joseph M. Castellano et al.   JAMA Neurology

Aging and brain rejuvenation as systemic events

(2014) Jill Bouchard et al.   JOURNAL OF NEUROCHEMISTRY

Young blood reverses age-related impairments in cognitive function and synaptic plasticity in mice

(2014) Saul A Villeda et al.   NATURE MEDICINE

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

(2014) L. Katsimpardi et al.   SCIENCE

The Hallmarks of Aging

(2013) Carlos López-Otín et al.   CELL

Depression in the elderly

(2013) Nicholas Q. Vu et al.   CURRENT OPINION IN NEUROLOGY

The Brain on Stress: Vulnerability and Plasticity of the Prefrontal Cortex over the Life Course

(2013) Bruce S. McEwen et al.   NEURON

The circulatory systemic environment as a modulator of neurogenesis and brain aging

(2012) Saul A. Villeda et al.   AUTOIMMUNITY REVIEWS

Increased Expression of the Anti-Apoptotic Protein Bcl-xL in the Brain is Associated with Resilience to Stress-Induced Depression-Like Behavior

(2012) Nikolay N. Dygalo et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Effects of fluoxetine on plasticity and apoptosis evoked by chronic stress in rat prefrontal cortex

(2012) Ana Djordjevic et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Neuroinflammation, Neurodegeneration, and Depression

(2012) Laura L. Hurley et al.   NEUROTOXICITY RESEARCH

The ageing systemic milieu negatively regulates neurogenesis and cognitive function

(2011) Saul A. Villeda et al.   NATURE

Prefrontal cortex, caloric restriction and stress during aging: Studies on dopamine and acetylcholine release, BDNF and working memory

(2010) Alberto Del Arco et al.   BEHAVIOURAL BRAIN RESEARCH

Neural mechanisms of ageing and cognitive decline

(2010) Nicholas A. Bishop et al.   NATURE

In animal models, psychosocial stress-induced (neuro)inflammation, apoptosis and reduced neurogenesis are associated to the onset of depression

(2010) Marta Kubera et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Effects of β-carboline harmine on behavioral and physiological parameters observed in the chronic mild stress model: Further evidence of antidepressant properties

(2009) Jucélia J. Fortunato et al.   BRAIN RESEARCH BULLETIN

Morphometric analysis of neuronal and glial cell pathology in the dorsolateral prefrontal cortex in late-life depression

(2009) Ahmad Khundakar et al.   BRITISH JOURNAL OF PSYCHIATRY

Blood-brain barrier alterations in ageing and dementia

(2009) Bogdan O. Popescu et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

“Killing the Blues”: A role for cellular suicide (apoptosis) in depression and the antidepressant response?

(2009) Declan P. McKernan et al.   PROGRESS IN NEUROBIOLOGY

Chronic unpredictable stress promotes neuronal apoptosis in the cerebral cortex

(2008) Alessia Bachis et al.   NEUROSCIENCE LETTERS