FDA-approved 5-HT1F receptor agonist lasmiditan induces mitochondrial biogenesis and enhances locomotor and blood-spinal cord barrier recovery after spinal cord injury

Mitochondrial biogenesis as a therapeutic target for traumatic and neurodegenerative CNS diseases

(2020) Epiphani C. Simmons et al.   EXPERIMENTAL NEUROLOGY

Interim results of a prospective, randomized, open-label, Phase 3 study of the long-term safety and efficacy of lasmiditan for acute treatment of migraine (the GLADIATOR study)

(2019) Jan Lewis Brandes et al.   CEPHALALGIA

β2-adrenergic receptor-mediated mitochondrial biogenesis improves skeletal muscle recovery following spinal cord injury

(2019) Natalie E. Scholpa et al.   EXPERIMENTAL NEUROLOGY

Lasmiditan for acute treatment of migraine in patients with cardiovascular risk factors: post-hoc analysis of pooled results from 2 randomized, double-blind, placebo-controlled, phase 3 trials

(2019) Robert E. Shapiro et al.   JOURNAL OF HEADACHE AND PAIN

The 5-hydroxytryptamine receptor 1F stimulates mitochondrial biogenesis and angiogenesis in endothelial cells

(2019) Tess V. Dupre et al.   BIOCHEMICAL PHARMACOLOGY

Endothelial progenitor cell-conditioned medium promotes angiogenesis and is neuroprotective after spinal cord injury

(2018) Zong-Sheng Yin et al.   Neural Regeneration Research

Synchrotron Radiation Imaging Reveals the Role of Estrogen in Promoting Angiogenesis After Acute Spinal Cord Injury in Rats

(2018) Shuangfei Ni et al.   SPINE

Hydrogen Sulfide Ameliorates Blood-Spinal Cord Barrier Disruption and Improves Functional Recovery by Inhibiting Endoplasmic Reticulum Stress-Dependent Autophagy

(2018) Haoli Wang et al.   Frontiers in Pharmacology

Pharmacological Stimulation of Mitochondrial Biogenesis Using the Food and Drug Administration-Approved β2-Adrenoreceptor Agonist Formoterol for the Treatment of Spinal Cord Injury

(2018) Natalie E. Scholpa et al.   JOURNAL OF NEUROTRAUMA

Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice

(2018) Jessica C Oswald et al.   Journal of Pain Research

Pioglitazone treatment following spinal cord injury maintains acute mitochondrial integrity and increases chronic tissue sparing and functional recovery

(2017) Samir P. Patel et al.   EXPERIMENTAL NEUROLOGY

Mitochondrial-Based Therapeutics for the Treatment of Spinal Cord Injury: Mitochondrial Biogenesis as a Potential Pharmacological Target

(2017) Natalie E. Scholpa et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Matrix Metalloproteinase-8 Inhibition Prevents Disruption of Blood–Spinal Cord Barrier and Attenuates Inflammation in Rat Model of Spinal Cord Injury

(2017) Hemant Kumar et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial Biogenesis as a Pharmacological Target: A New Approach to Acute and Chronic Diseases

(2016) Ryan M. Whitaker et al.   Annual Review of Pharmacology and Toxicology

Propitious Therapeutic Modulators to Prevent Blood-Spinal Cord Barrier Disruption in Spinal Cord Injury

(2016) Hemant Kumar et al.   MOLECULAR NEUROBIOLOGY

Effect of lycopene on the blood-spinal cord barrier after spinal cord injury in mice

(2016) Qian Zhang et al.   BioScience Trends

The cross-talk between autophagy and endoplasmic reticulum stress in blood-spinal cord barrier disruption after spinal cord injury

(2016) Yulong Zhou et al.   Oncotarget

Peripheral and spinal 5-HT receptors participate in cholestatic itch and antinociception induced by bile duct ligation in rats

(2016) Bin Tian et al.   Scientific Reports

Dexmedetomidine Attenuates Blood-Spinal Cord Barrier Disruption Induced by Spinal Cord Ischemia Reperfusion Injury in Rats

(2015) Bo Fang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Neuroprotective effect of ketamine on acute spinal cord injury in rats

(2015) S.H. Tang et al.   GENETICS AND MOLECULAR RESEARCH

Acute Spinal Cord Injury

(2015) Christopher D. Witiw et al.   JOURNAL OF SPINAL DISORDERS & TECHNIQUES

Paclitaxel inhibits mRNA transport in axons

(2015) Ilja Bobylev et al.   NEUROBIOLOGY OF DISEASE

The Neuroprotective Effect of Tetramethylpyrazine Against Contusive Spinal Cord Injury by Activating PGC-1α in Rats

(2015) Jianzhong Hu et al.   NEUROCHEMICAL RESEARCH

Hypoxic Induction of Vascular Endothelial Growth Factor (VEGF) and Angiogenesis in Muscle by Truncated Peroxisome Proliferator-activated Receptor γ Coactivator (PGC)-1α

(2014) Robyn Thom et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Characterization of Vascular Disruption and Blood–Spinal Cord Barrier Permeability following Traumatic Spinal Cord Injury

(2013) Sarah A. Figley et al.   JOURNAL OF NEUROTRAUMA

PGC-1α Regulates Normal and Pathological Angiogenesis in the Retina

(2012) Magali Saint-Geniez et al.   AMERICAN JOURNAL OF PATHOLOGY

Polysynaptic excitatory postsynaptic potentials that trigger spasms after spinal cord injury in rats are inhibited by 5-HT1B and 5-HT1F receptors

(2011) Katherine C. Murray et al.   JOURNAL OF NEUROPHYSIOLOGY

Pharmacological interventions for spinal cord injury: Where do we stand? How might we step forward?

(2011) Alexander G. Rabchevsky et al.   PHARMACOLOGY & THERAPEUTICS

A high-throughput respirometric assay for mitochondrial biogenesis and toxicity

(2010) Craig C. Beeson et al.   ANALYTICAL BIOCHEMISTRY

Effect of VEGF Treatment on the Blood-Spinal Cord Barrier Permeability in Experimental Spinal Cord Injury: Dynamic Contrast-Enhanced Magnetic Resonance Imaging

(2009) Chirag B. Patel et al.   JOURNAL OF NEUROTRAUMA

5-Hydroxytryptamine Receptor Stimulation of Mitochondrial Biogenesis

(2009) K. A. Rasbach et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Isoflavones Promote Mitochondrial Biogenesis

(2008) K. A. Rasbach et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Blood-spinal cord barrier permeability in experimental spinal cord injury: dynamic contrast-enhanced MRI

(2008) David M. Cohen et al.   NMR IN BIOMEDICINE