Lutein and zeaxanthin reduce A2E and iso-A2E levels and improve visual performance in Abca4/Bco2 double knockout mice

Effects of deficiency in the RLBP1-encoded visual cycle protein CRALBP on visual dysfunction in humans and mice

(2020) Jose Ronaldo Lima de Carvalho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Imaging lutein and zeaxanthin in the human retina with confocal resonance Raman microscopy

(2020) Binxing Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The emerging roles of the macular pigment carotenoids throughout the lifespan and in prenatal supplementation

(2020) Paul S. Bernstein et al.   JOURNAL OF LIPID RESEARCH

The human mitochondrial enzyme BCO2 exhibits catalytic activity towards carotenoids and apocarotenoids

(2020) Linda D Thomas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Toxicity of blue led light and A2E is associated to mitochondrial dynamics impairment in ARPE-19 cells: implications for age-related macular degeneration

(2019) Agustina Alaimo et al.   ARCHIVES OF TOXICOLOGY

Supplementation with macular carotenoids improves visual performance of transgenic mice

(2018) Binxing Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A2E-associated cell death and inflammation in retinal pigmented epithelial cells from human induced pluripotent stem cells

(2018) Vipul M. Parmar et al.   Stem Cell Research

Conversion of all-trans-retinal into all-trans-retinal dimer reflects an alternative metabolic/antidotal pathway of all-trans-retinal in the retina

(2018) Zhan Gao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retinal accumulation of zeaxanthin, lutein, and β-carotene in mice deficient in carotenoid cleavage enzymes

(2017) Binxing Li et al.   EXPERIMENTAL EYE RESEARCH

RPE65 has an additional function as the lutein tomeso-zeaxanthin isomerase in the vertebrate eye

(2017) Rajalekshmy Shyam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Towards Treatment of Stargardt Disease: Workshop Organized and Sponsored by the Foundation Fighting Blindness

(2017) Avery E. Sears et al.   Translational Vision Science & Technology

Vitamin A-aldehyde adducts: AMD risk and targeted therapeutics

(2016) Janet R. Sparrow   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photodegradation of retinal bisretinoids in mouse models and implications for macular degeneration

(2016) Keiko Ueda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lutein, zeaxanthin, and meso-zeaxanthin: The basic and clinical science underlying carotenoid-based nutritional interventions against ocular disease

(2016) Paul S. Bernstein et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Inactivity of human  , -carotene-9',10'-dioxygenase (BCO2) underlies retinal accumulation of the human macular carotenoid pigment

(2014) B. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chemistry of the Retinoid (Visual) Cycle

(2013) Philip D. Kiser et al.   CHEMICAL REVIEWS

Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration

(2013) P. Barabas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lutein and zeaxanthin supplementation reduces photooxidative damage and modulates the expression of inflammation-related genes in retinal pigment epithelial cells

(2012) Qingning Bian et al.   FREE RADICAL BIOLOGY AND MEDICINE

Complement System Dysregulation and Inflammation in the Retinal Pigment Epithelium of a Mouse Model for Stargardt Macular Degeneration

(2011) Roxana A. Radu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The bisretinoids of retinal pigment epithelium

(2011) Janet R. Sparrow et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Studies on the singlet oxygen scavenging mechanism of human macular pigment

(2010) Binxing Li et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Mass spectrometry provides accurate and sensitive quantitation of A2E

(2010) Danielle B. Gutierrez et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Blue light induced A2E oxidation in rat eyes – experimental animal model of dry AMD

(2010) A. R. Wielgus et al.   PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES

Structural characterization of bisretinoid A2E photocleavage products and implications for age-related macular degeneration

(2010) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel Lipofuscin Bisretinoids Prominent in Human Retina and in a Model of Recessive Stargardt Disease

(2009) Yalin Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues

(2008) Maureen A. Kane et al.   ANALYTICAL BIOCHEMISTRY

Retinal carotenoids can attenuate formation of A2E in the retinal pigment epithelium

(2008) Prakash Bhosale et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Lycopene Biodistribution Is Altered in 15,15′-Carotenoid Monooxygenase Knockout Mice

(2008) Brian L. Lindshield et al.   JOURNAL OF NUTRITION

The Phototoxicity of Aged Human Retinal Melanosomes

(2008) Bartosz Różanowski et al.   PHOTOCHEMISTRY AND PHOTOBIOLOGY

Rodent electroretinography: Methods for extraction and interpretation of rod and cone responses

(2007) A WEYMOUTH et al.   PROGRESS IN RETINAL AND EYE RESEARCH