Role of sex hormones in lung cancer

Cancer Statistics, 2021

(2021) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Plausible Role of Estrogens in Pathogenesis, Progression and Therapy of Lung Cancer

(2021) Claudia Musial et al.   International Journal of Environmental Research and Public Health

The Role of Anti-angiogenesis in the Treatment Landscape of Non-small Cell Lung Cancer – New Combinational Approaches and Strategies of Neovessel Inhibition

(2021) Sophia Daum et al.   Frontiers in Cell and Developmental Biology

Screening for Lung Cancer

(2021) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

miR-224-5p-enriched exosomes promote tumorigenesis by directly targeting androgen receptor in non-small cell lung cancer

(2021) Jinbao Zhou et al.   Molecular Therapy-Nucleic Acids

Lung cancer incidence in young women vs . young men: A systematic analysis in 40 countries

(2020) Miranda M. Fidler‐Benaoudia et al.   INTERNATIONAL JOURNAL OF CANCER

Lung cancer incidence and mortality in relationship to hormone replacement therapy use among women participating in the PLCO trial: a post hoc analysis

(2020) Omar Abdel-Rahman   International Journal of Clinical Oncology

Influence of Estrogen on the NSCLC Microenvironment: A Comprehensive Picture and Clinical Implications

(2020) Tanner Smida et al.   Frontiers in Oncology

Female reproductive factors and the risk of lung cancer in postmenopausal women: a nationwide cohort study

(2020) Keun Hye Jeon et al.   BRITISH JOURNAL OF CANCER

Brigatinib Versus Crizotinib in Advanced ALK Inhibitor–Naive ALK-Positive Non–Small Cell Lung Cancer: Second Interim Analysis of the Phase III ALTA-1L Trial

(2020) D. Ross Camidge et al.   JOURNAL OF CLINICAL ONCOLOGY

Androgen and Androgen Receptors as Regulators of Monocyte and Macrophage Biology in the Healthy and Diseased Lung

(2020) Mireya Becerra-Diaz et al.   Frontiers in Immunology

Molecular Pathology of Primary Non-small Cell Lung Cancer

(2020) David Ilan Suster et al.   ARCHIVES OF MEDICAL RESEARCH

Atezolizumab Versus Docetaxel in Pretreated Patients With NSCLC: Final Results From the Randomized Phase 2 POPLAR and Phase 3 OAK Clinical Trials

(2020) Julien Mazieres et al.   Journal of Thoracic Oncology

Sex-based heterogeneity in response to lung cancer immunotherapy: a systematic review and meta-analysis

(2019) Fabio Conforti et al.   JNCI-Journal of the National Cancer Institute

Sex Differences in Cancer Immunotherapy Efficacy, Biomarkers, and Therapeutic Strategy

(2019) Shixiang Wang et al.   MOLECULES

Sex‐specificity in lung cancer risk

(2019) Claudia Stapelfeld et al.   INTERNATIONAL JOURNAL OF CANCER

The influence of hormone replacement therapy on lung cancer incidence and mortality

(2019) Ashley L. Titan et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Gene network approach reveals co-expression patterns in nasal and bronchial epithelium

(2019) Kai Imkamp et al.   Scientific Reports

Novel molecular targets for the treatment of lung cancer

(2019) Rafael Rosell et al.   CURRENT OPINION IN ONCOLOGY

Hormone replacement therapy and lung cancer risk in women

(2019) Chao Jin et al.   MEDICINE

A Real-World Study in Advanced Non–Small Cell Lung Cancer with KRAS Mutations

(2019) Lei Lei et al.   Translational Oncology

17β-estradiol upregulates IL6 expression through the ERβ pathway to promote lung adenocarcinoma progression

(2018) Quanfu Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Updated Molecular Testing Guideline for the Selection of Lung Cancer Patients for Treatment With Targeted Tyrosine Kinase Inhibitors

(2018) Neal I. Lindeman et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC

(2018) Mark A. Socinski et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influence of estrogen in non-small cell lung cancer and its clinical implications

(2018) Vianey Rodriguez-Lara et al.   Journal of Thoracic Disease

Current Cigarette Smoking Among Adults — United States, 2016

(2018) Ahmed Jamal et al.   MMWR-MORBIDITY AND MORTALITY WEEKLY REPORT

Lung-Enriched Mutations in the p53 Tumor Suppressor: A Paradigm for Tissue-Specific Gain of Oncogenic Function

(2018) Julie A. Barta et al.   MOLECULAR CANCER RESEARCH

Lung Cancers: Molecular Characterization, Clonal Heterogeneity and Evolution, and Cancer Stem Cells

(2018) Ugo Testa et al.   Cancers

Clinical Relevance of EGFR- or KRAS-mutated Subclones in Patients With Advanced Non–small-cell Lung Cancer Receiving Erlotinib in a French Prospective Cohort (IFCT ERMETIC2 Cohort - Part 2)

(2018) Michèle Beau-Faller et al.   Clinical Lung Cancer

Endocrine regulation of lung disease and inflammation

(2018) Nathalie Fuentes et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Androgen and Androgen Receptor as Enhancers of M2 Macrophage Polarization in Allergic Lung Inflammation

(2018) Mireya Becerra-Díaz et al.   JOURNAL OF IMMUNOLOGY

Lymph/angiogenesis contributes to sex differences in lung cancer through oestrogen receptor alpha signalling

(2018) Charline Dubois et al.   ENDOCRINE-RELATED CANCER

Targeted therapies in non-small cell lung cancer: a focus on ALK/ROS1 tyrosine kinase inhibitors

(2017) Assunta Sgambato et al.   Expert Review of Anticancer Therapy

Estrogen, Estrogen Receptor and Lung Cancer

(2017) Li-Han Hsu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Non–Small Cell Lung Cancer, Version 5.2017, NCCN Clinical Practice Guidelines in Oncology

(2017) David S. Ettinger et al.   Journal of the National Comprehensive Cancer Network

Atezolizumab versus docetaxel in patients with previously treated non-small-cell lung cancer (OAK): a phase 3, open-label, multicentre randomised controlled trial

(2017) Achim Rittmeyer et al.   LANCET

Corrigendum: High-throughput discovery of novel developmental phenotypes

(2017) Mary E. Dickinson et al.   NATURE

G-Protein-Coupled Estrogen Receptor Antagonist G15 Decreases Estrogen-Induced Development of Non-Small Cell Lung Cancer

(2017) Changyu Liu et al.   ONCOLOGY RESEARCH

ROS1 protein-tyrosine kinase inhibitors in the treatment of ROS1 fusion protein-driven non-small cell lung cancers

(2017) Robert Roskoski   PHARMACOLOGICAL RESEARCH

Treatment advances in small cell lung cancer (SCLC)

(2017) Saiama N. Waqar et al.   PHARMACOLOGY & THERAPEUTICS

The sexist behaviour of immune checkpoint inhibitors in cancer therapy?

(2017) Andrea Botticelli et al.   Oncotarget

Estrogen metabolism in the human lung: impact of tumorigenesis, smoke, sex and race/ethnicity

(2017) Jing Peng et al.   Oncotarget

Estrogen Plus Progestin and Lung Cancer: Follow-up of the Women's Health Initiative Randomized Trial

(2016) Rowan T. Chlebowski et al.   Clinical Lung Cancer

Study Design and Rationale for a Randomized, Placebo-Controlled, Double-Blind Study to Assess the Efficacy and Safety of Selumetinib in Combination With Docetaxel as Second-Line Treatment in Patients With KRAS-Mutant Advanced Non-Small Cell Lung Cancer (SELECT-1)

(2016) Pasi A. Jänne et al.   Clinical Lung Cancer

Pulmonary health effects of air pollution

(2016) Ozlem Kar Kurt et al.   CURRENT OPINION IN PULMONARY MEDICINE

Risk factors for lung cancer worldwide

(2016) Jyoti Malhotra et al.   EUROPEAN RESPIRATORY JOURNAL

Trends in Subpopulations at High Risk for Lung Cancer

(2016) Ping Yang et al.   Journal of Thoracic Oncology

Analysis of ultra-deep targeted sequencing reveals mutation burden is associated with gender and clinical outcome in lung adenocarcinoma

(2016) Dakai Xiao et al.   Oncotarget

KRAS Mutation in Small Cell Lung Carcinoma and Extrapulmonary Small Cell Cancer

(2016) Hilmi Kodaz et al.   Balkan Medical Journal

Estrogen receptor-β in mitochondria: implications for mitochondrial bioenergetics and tumorigenesis

(2015) Tien-Ling Liao et al.   Annals of the New York Academy of Sciences

Convergence of decreasing male and increasing female incidence rates in major tobacco-related cancers in Europe in 1988–2010

(2015) Joannie Lortet-Tieulent et al.   EUROPEAN JOURNAL OF CANCER

AZD9291 in EGFR Inhibitor–Resistant Non–Small-Cell Lung Cancer

(2015) Pasi A. Jänne et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sex steroid signaling: Implications for lung diseases

(2015) Venkatachalem Sathish et al.   PHARMACOLOGY & THERAPEUTICS

The prognostic role of progesterone receptor expression in non-small cell lung cancer patients: Gender-related impacts and correlation with disease-specific survival

(2015) Kaja Skjefstad et al.   STEROIDS

Nuclear estrogen receptor-α expression is an independent predictor of recurrence in male patients with pT1aN0 lung adenocarcinomas, and correlates with regulatory T-cell infiltration

(2015) Kyuichi Kadota et al.   Oncotarget

Ceritinib for the treatment of patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer

(2015) Lorenza Landi et al.   Expert Review of Clinical Pharmacology

Lung Cancer Incidence Trends by Gender, Race and Histology in the United States, 1973–2010

(2015) Rafael Meza et al.   PLoS One

Estrogen Receptor Beta and CXCR4/CXCL12 Expression: Differences by Sex and Hormonal Status in Lung Adenocarcinoma

(2014) Vianey Rodriguez-Lara et al.   ARCHIVES OF MEDICAL RESEARCH

Estrogen adversely affects the prognosis of patients with lung adenocarcinoma

(2014) Li-Han Hsu et al.   CANCER SCIENCE

Survival in Women with NSCLC: The Role of Reproductive History and Hormone Use

(2014) Hannah Katcoff et al.   Journal of Thoracic Oncology

Mitochondrial estrogen receptor β inhibits cell apoptosis via interaction with Bad in a ligand-independent manner

(2014) Jiayi Liang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Smoking Out Reproductive Hormone Actions in Lung Cancer

(2014) Jill M. Siegfried   MOLECULAR CANCER RESEARCH

Menopausal Hormone Therapy and Lung Cancer-Specific Mortality Following Diagnosis: The California Teachers Study

(2014) Jessica Clague et al.   PLoS One

A phase-1b study of everolimus plus paclitaxel in patients with small-cell lung cancer

(2013) J M Sun et al.   BRITISH JOURNAL OF CANCER

Epidemiology of Lung Cancer

(2013) Anthony J. Alberg et al.   CHEST

Analysis of Tumor Specimens at the Time of Acquired Resistance to EGFR-TKI Therapy in 155 Patients with EGFR-Mutant Lung Cancers

(2013) H. A. Yu et al.   CLINICAL CANCER RESEARCH

Frequency of EGFR and KRAS mutations in patients with non small cell lung cancer by racial background: Do disparities exist?

(2013) Joshua Bauml et al.   LUNG CANCER

Androgen receptor (AR) differential roles in hormone-related tumors including prostate, bladder, kidney, lung, breast and liver

(2013) C Chang et al.   ONCOGENE

Estrogenic Steroid Hormones in Lung Cancer

(2013) Jill M. Siegfried et al.   SEMINARS IN ONCOLOGY

Lung Cancer in Women: Differences in Epidemiology, Biology, Histology, and Treatment Outcomes

(2013) M. Rivera   SEMINARS IN RESPIRATORY AND CRITICAL CARE MEDICINE

Unopposed estrogen and estrogen plus progestin menopausal hormone therapy and lung cancer risk in the NIH–AARP Diet and Health Study Cohort

(2012) Louise A. Brinton et al.   CANCER CAUSES & CONTROL

Associations between Testosterone Levels and Incident Prostate, Lung, and Colorectal Cancer. A Population-Based Study

(2012) Z. Hyde et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Sex Differences and Sex Steroids in Lung Health and Disease

(2012) Elizabeth A. Townsend et al.   ENDOCRINE REVIEWS

Combining the Multitargeted Tyrosine Kinase Inhibitor Vandetanib with the Antiestrogen Fulvestrant Enhances Its Antitumor Effect in Non-small Cell Lung Cancer

(2012) Jill M. Siegfried et al.   Journal of Thoracic Oncology

Impact of Systematic EGFR and KRAS Mutation Evaluation on Progression-Free Survival and Overall Survival in Patients with Advanced Non–Small-Cell Lung Cancer Treated by Erlotinib in a French Prospective Cohort (ERMETIC Project—Part 2)

(2012) Jacques Cadranel et al.   Journal of Thoracic Oncology

Targeting androgen receptor as a new potential therapeutic approach to battle tobacco carcinogens-induced non-small cell lung cancer

(2012) Shauh-Der Yeh et al.   Journal of Translational Medicine

Estrogen Signaling in Lung Cancer: An Opportunity for Novel Therapy

(2012) Christina S. Baik et al.   Cancers

Environmental chemicals and microRNAs

(2011) Lifang Hou et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Reproductive Factors, Hormone Use, and Risk for Lung Cancer in Postmenopausal Women, the Nurses' Health Study

(2010) C. S. Baik et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Gender-related disparities in non-small cell lung cancer

(2010) Marco G. Paggi et al.   CANCER LETTERS

Early Changes in Gene Expression Induced by Tobacco Smoke: Evidence for the Importance of Estrogen within Lung Tissue

(2010) S. I. Meireles et al.   Cancer Prevention Research

Early Changes in Pulmonary Gene Expression following Tobacco Exposure Shed Light on the Role of Estrogen Metabolism in Lung Carcinogenesis

(2010) J. M. Siegfried   Cancer Prevention Research

Phase II Study of Everolimus (RAD001) in Previously Treated Small Cell Lung Cancer

(2010) A. Tarhini et al.   CLINICAL CANCER RESEARCH

Combined Analysis of Estrogen Receptor  -1 and Progesterone Receptor Expression Identifies Lung Cancer Patients with Poor Outcome

(2010) L. P. Stabile et al.   CLINICAL CANCER RESEARCH

Sex differences in lung cancer susceptibility: A review

(2010) Chikako Kiyohara et al.   Gender Medicine

Clinical Relevance of KRAS in Human Cancers

(2010) Sylwia Jančík et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Ligand-Independent Antiapoptotic Function of Estrogen Receptor-β in Lung Cancer Cells

(2010) GuangFeng Zhang et al.   MOLECULAR ENDOCRINOLOGY

Inhibition of cyclin D1 expression by androgen receptor in breast cancer cells--identification of a novel androgen response element

(2010) M. Lanzino et al.   NUCLEIC ACIDS RESEARCH

Targeting Aromatase and Estrogen Signaling in Human Non-Small Cell Lung Cancer

(2009) Diana C. Márquez-Garbán et al.   Annals of the New York Academy of Sciences

Lung Cancer in Never Smokers: Clinical Epidemiology and Environmental Risk Factors

(2009) J. M. Samet et al.   CLINICAL CANCER RESEARCH

Oestrogen plus progestin and lung cancer in postmenopausal women (Women's Health Initiative trial): a post-hoc analysis of a randomised controlled trial

(2009) Rowan T Chlebowski et al.   LANCET

Small Cell Lung Cancer

(2009) Taimur Sher et al.   MAYO CLINIC PROCEEDINGS

Androgen receptor and androgen-dependent gene expression in lung

(2009) Laura Mikkonen et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Screening for Epidermal Growth Factor Receptor Mutations in Lung Cancer

(2009) Rafael Rosell et al.   NEW ENGLAND JOURNAL OF MEDICINE

Similarities and differences between smoking-related gene expression in nasal and bronchial epithelium

(2009) Xiaoling Zhang et al.   PHYSIOLOGICAL GENOMICS

Estrogen Receptor Signaling in Lung Cancer

(2009) Jill M. Siegfried et al.   SEMINARS IN ONCOLOGY

Gender-Associated Differences in Lung Cancer: Clinical Characteristics and Treatment Outcomes in Women

(2009) Seema Harichand-Herdt et al.   SEMINARS IN ONCOLOGY

Postmenopausal Hormone Therapy and Lung Cancer Risk in the Cancer Prevention Study II Nutrition Cohort

(2008) C. Rodriguez et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Annual Report to the Nation on the Status of Cancer, 1975–2005, Featuring Trends in Lung Cancer, Tobacco Use, and Tobacco Control

(2008) Ahmedin Jemal et al.   JNCI-Journal of the National Cancer Institute

Estrogen Receptor (ER) and Epidermal Growth Factor Receptor (EGFR) as Targets for Dual Lung Cancer Therapy: Not Just a Case?

(2008) Monica Giovannini et al.   Journal of Thoracic Oncology

Oestrogen receptor β over expression in males with non-small cell lung cancer is associated with better survival

(2007) Birgit Guldhammer Skov et al.   LUNG CANCER