Clinical Relevance of KRAS in Human Cancers

Using Whole Genome Amplification (WGA) of Low-Volume Biopsies to Assess the Prognostic Role of EGFR, KRAS, p53, and CMET Mutations in Advanced-Stage Non-small Cell Lung Cancer (NSCLC)

(2010) Elaine H. Lim et al.   Journal of Thoracic Oncology

COLD-PCR: a new platform for highly improved mutation detection in cancer and genetic testing

(2009) Jin Li et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Mutation scanning using high-resolution melting

(2009) Claire F. Taylor   BIOCHEMICAL SOCIETY TRANSACTIONS

Detection of K-Ras mutations in tumour samples of patients with non-small cell lung cancer using PNA-mediated PCR clamping

(2009) M Beau-Faller et al.   BRITISH JOURNAL OF CANCER

Recent advances of novel targeted therapy in non-small cell lung cancer

(2009) Jed A Katzel et al.   Journal of Hematology & Oncology

Activated kRas protects colon cancer cells from cucurbitacin-induced apoptosis: The role of p53 and p21

(2008) José M. Escandell et al.   BIOCHEMICAL PHARMACOLOGY

Clinical target promiscuity: lessons from ras molecular trials

(2008) Ramesh Rengan et al.   CANCER AND METASTASIS REVIEWS

U.S. Food and Drug Administration Approval: Panitumumab for Epidermal Growth Factor Receptor-Expressing Metastatic Colorectal Carcinoma with Progression Following Fluoropyrimidine-, Oxaliplatin-, and Irinotecan-Containing Chemotherapy Regimens

(2008) R. M. Giusti et al.   CLINICAL CANCER RESEARCH

Farnesyltransferase Inhibitors: A Detailed Chemical View on an Elusive Biological Problem

(2008) Sergio Sousa et al.   CURRENT MEDICINAL CHEMISTRY

The status and role of ErbB receptors in human cancer

(2008) I. Überall et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

High Detection Rates of Colorectal Neoplasia by Stool DNA Testing With a Novel Digital Melt Curve Assay

(2008) Hongzhi Zou et al.   GASTROENTEROLOGY

Rapid identification of somatic mutations in colorectal and breast cancer tissues using mismatch repair detection (MRD)

(2008) Steven Bentivegna et al.   HUMAN MUTATION

KRASMutations As an Independent Prognostic Factor in Patients With Advanced Colorectal Cancer Treated With Cetuximab

(2008) Astrid Lièvre et al.   JOURNAL OF CLINICAL ONCOLOGY

Wild-TypeKRASIs Required for Panitumumab Efficacy in Patients With Metastatic Colorectal Cancer

(2008) Rafael G. Amado et al.   JOURNAL OF CLINICAL ONCOLOGY

Rapid Screening Assay for KRAS Mutations by the Modified Smart Amplification Process

(2008) Kenji Tatsumi et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

An activating KRAS mutation in imatinib-resistant chronic myeloid leukemia

(2008) A Agarwal et al.   LEUKEMIA

Epidermal Growth Factor Receptor Monoclonal Antibodies for the Treatment of Metastatic Colorectal Cancer

(2008) Gary W Jean et al.   PHARMACOTHERAPY

Epidermal Growth Factor Receptor as a Predictor of Tumor Response to Preoperative Chemoradiation in Locally Advanced Gastric Carcinoma

(2008) Igor Sirak et al.   STRAHLENTHERAPIE UND ONKOLOGIE