A differential equation based modelling approach to predict supersaturation and in vivo absorption from in vitro dissolution-absorption system (idas2) data

Effect of common excipients on intestinal drug absorption in Wistar rats.

(2020) Alejandro Ruiz-Picazo et al.   MOLECULAR PHARMACEUTICS

On the Usefulness of Two Small-Scale In Vitro Setups in the Evaluation of Luminal Precipitation of Lipophilic Weak Bases in Early Formulation Development

(2020) Patrick J. O’Dwyer et al.   Pharmaceutics

Suitability of the z-Factor for Dissolution Simulation of Solid Oral Dosage Forms: Potential Pitfalls and Refinements

(2020) Martin A. Hofsäss et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Simultaneous Analysis of Dissolution and Permeation Profiles of Nanosized and Microsized Formulations of Indomethacin Using the In Vitro Dissolution Absorption System 2

(2019) Jibin Li et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Application of an automated small-scale in vitro transfer model to predict in vivo precipitation inhibition

(2019) Christian Jede et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Biphasic drug release testing coupled with diffusing wave spectroscopy for mechanistic understanding of solid dispersion performance

(2019) Sandra Jankovic et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

In Vitro and In Vivo Assessment of the Potential of Supersaturation to Enhance the Absorption of Poorly Soluble Basic Drugs

(2019) Jibin Li et al.   Journal of Pharmaceutical Innovation

Near infrared (NIR)-spectroscopy and in-vitro dissolution absorption system 2 (IDAS2) can help detect changes in the quality of generic drugs

(2019) Carlos Jiménez-Romero et al.   DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY

In vitro dissolution absorption system (IDAS2): Use for the prediction of food viscosity effects on drug dissolution and absorption from oral solid dosage forms

(2019) Svitlana Silchenko et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Impact of Physicochemical Properties of Cellulosic Polymers on Supersaturation Maintenance in Aqueous Drug Solutions

(2018) Shiqi Hong et al.   AAPS PHARMSCITECH

In Vitro-In Vivo Predictive Dissolution-Permeation-Absorption Dynamics of Highly Permeable Drug Extended-Release Tablets via Drug Dissolution/Absorption Simulating System and pH Alteration

(2018) Zi-qiang Li et al.   AAPS PHARMSCITECH

Acute Exposure to Commonly Ingested Emulsifiers Alters Intestinal Mucus Structure and Transport Properties

(2018) Jaclyn Y. Lock et al.   Scientific Reports

Integration of Precipitation Kinetics From an In Vitro, Multicompartment Transfer System and Mechanistic Oral Absorption Modeling for Pharmacokinetic Prediction of Weakly Basic Drugs

(2018) Sanjaykumar Patel et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

In vitro models for the prediction of in vivo performance of oral dosage forms: Recent progress from partnership through the IMI OrBiTo collaboration

(2018) James Butler et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Dynamic dissolution-/permeation-testing of nano- and microparticle formulations of fenofibrate

(2017) Daniel Sironi et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Cytotoxicity assessment of lipid-based self-emulsifying drug delivery system with Caco-2 cell model: Cremophor EL as the surfactant

(2016) Pengli Bu et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Effects of gastric pH on oral drug absorption: In vitro assessment using a dissolution/permeation system reflecting the gastric dissolution process

(2016) Makoto Kataoka et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Advantage of the Dissolution/Permeation System for Estimating Oral Absorption of Drug Candidates in the Drug Discovery Stage

(2016) Yoshihiro Miyaji et al.   MOLECULAR PHARMACEUTICS

Development of a Unified Dissolution and Precipitation Model and Its Use for the Prediction of Oral Drug Absorption

(2016) Paulina Jakubiak et al.   MOLECULAR PHARMACEUTICS

Concomitant intake of alcohol may increase the absorption of poorly soluble drugs

(2015) Jonas H. Fagerberg et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

In Situ Perfusion Model in Rat Colon for Drug Absorption Studies: Comparison with Small Intestine and Caco-2 Cell Model

(2015) Isabel Lozoya-Agullo et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

The Effect of Excipients on the Permeability of BCS Class III Compounds and Implications for Biowaivers

(2015) Alan Parr et al.   PHARMACEUTICAL RESEARCH

In vivo methods for drug absorption – Comparative physiologies, model selection, correlations with in vitro methods (IVIVC), and applications for formulation/API/excipient characterization including food effects

(2014) Erik Sjögren et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

A new in vitro system for evaluation of passive intestinal drug absorption: Establishment of a double artificial membrane permeation assay

(2014) Makoto Kataoka et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Application of a continuous intrinsic dissolution–permeation system for relative bioavailability estimation of polymorphic drugs

(2014) Yuefang Zhou et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

A Combination Turbidity and Supernatant Microplate Assay to Rank‐Order the Supersaturation Limits of Early Drug Candidates

(2014) John S. Morrison et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Mechanistic analysis of solute transport in anin vitrophysiological two-phase dissolution apparatus

(2012) Deanna M. Mudie et al.   BIOPHARMACEUTICS & DRUG DISPOSITION

Drug precipitation–permeation interplay: Supersaturation in an absorptive environment

(2012) Jan Bevernage et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

PKSolver: An add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel

(2010) Yong Zhang et al.   COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE

Computational oral absorption simulation of free base drugs

(2010) Kiyohiko Sugano   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in-vivo experiments

(2007) Emma L. McConnell et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY