Water-soluble derivatives of evodiamine: Discovery of evodiamine-10-phosphate as an orally active antitumor lead compound

Discovery of 4-Aminoquinoline-3-carboxamide Derivatives as Potent Reversible Bruton’s Tyrosine Kinase Inhibitors for the Treatment of Rheumatoid Arthritis

(2019) Xia Yao et al.   JOURNAL OF MEDICINAL CHEMISTRY

Novel fluorescent probes of 10-hydroxyevodiamine: Autophagy and apoptosis-inducing anticancer mechanisms

(2018) Shuqiang Chen et al.   Acta Pharmaceutica Sinica B

Producing irreversible topoisomerase II-mediated DNA breaks by site-specific Pt(II)-methionine coordination chemistry

(2017) Ying-Ren Wang et al.   NUCLEIC ACIDS RESEARCH

The structural modification of natural products for novel drug discovery

(2016) Hong Yao et al.   Expert Opinion on Drug Discovery

Scaffold Diversity Inspired by the Natural Product Evodiamine: Discovery of Highly Potent and Multitargeting Antitumor Agents

(2015) Shengzheng Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Theranostic etoposide phosphate/indium nanoparticles for cancer therapy and imaging

(2015) Ramishetti Srinivas et al.   Nanoscale

Target identification and mechanism of action in chemical biology and drug discovery

(2013) Monica Schenone et al.   Nature Chemical Biology

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

(2012) Guoqiang Dong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evodiamine improves congnitive abilities in SAMP8 and APPswe/PS1ΔE9 transgenic mouse models of Alzheimer's disease

(2011) Shu-min Yuan et al.   ACTA PHARMACOLOGICA SINICA

Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

(2010) Guoqiang Dong et al.   JOURNAL OF MEDICINAL CHEMISTRY

Conformationally Constrained Peptidomimetic Inhibitors of Signal Transducer and Activator of Transcription 3: Evaluation and Molecular Modeling

(2009) Pijus K. Mandal et al.   JOURNAL OF MEDICINAL CHEMISTRY