Corticosteroid modulation of immunoglobulin expression and B-cell function in COPD

Asthma–COPD Overlap. Clinical Relevance of Genomic Signatures of Type 2 Inflammation in Chronic Obstructive Pulmonary Disease

(2015) Stephanie A. Christenson et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dysfunction of the Reciprocal Feedback Loop between GATA3- and ZEB2-Nucleated Repression Programs Contributes to Breast Cancer Metastasis

(2015) Wenzhe Si et al.   CANCER CELL

Blood eosinophil counts, exacerbations, and response to the addition of inhaled fluticasone furoate to vilanterol in patients with chronic obstructive pulmonary disease: a secondary analysis of data from two parallel randomised controlled trials

(2015) Steven Pascoe et al.   Lancet Respiratory Medicine

Dual-specificity phosphatases: critical regulators with diverse cellular targets

(2015) Kate I. Patterson et al.   BIOCHEMICAL JOURNAL

Withdrawal of Inhaled Glucocorticoids and Exacerbations of COPD

(2014) Helgo Magnussen et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Dynamic Bronchial Airway Gene Expression Signature of Chronic Obstructive Pulmonary Disease and Lung Function Impairment

(2013) Katrina Steiling et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of Fluticasone With and Without Salmeterol on Pulmonary Outcomes in Chronic Obstructive Pulmonary Disease

(2013) Thérèse S. Lapperre   ANNALS OF INTERNAL MEDICINE

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Development of New Drugs for COPD

(2013) Peter J. Barnes   CURRENT MEDICINAL CHEMISTRY

Regulation of Wnt4 in chronic obstructive pulmonary disease

(2013) Andrew L. Durham et al.   FASEB JOURNAL

Inhaled long-acting β2 agonists enhance glucocorticoid receptor nuclear translocation and efficacy in sputum macrophages in COPD

(2013) Rubaiyat Haque et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Airway gene expression in COPD is dynamic with inhaled corticosteroid treatment and reflects biological pathways associated with disease activity

(2013) Maarten van den Berge et al.   THORAX

Corticosteroid Resistance and Novel Anti-Inflammatory Therapies in Chronic Obstructive Pulmonary Disease

(2012) Amir Hakim et al.   DRUGS

The role of bronchodilator treatment in the prevention of exacerbations of COPD

(2012) Jadwiga A. Wedzicha et al.   EUROPEAN RESPIRATORY JOURNAL

Mechanisms of the anti-inflammatory effects of glucocorticoids: genomic and nongenomic interference with MAPK signaling pathways

(2012) Emira Ayroldi et al.   FASEB JOURNAL

The Transcription Factor GATA-3 Controls Cell Fate and Maintenance of Type 2 Innate Lymphoid Cells

(2012) Thomas Hoyler et al.   IMMUNITY

Non-Classical P38 Map Kinase Functions: Cell Cycle Checkpoints and Survival

(2012) Tina M. Thornton et al.   International Journal of Biological Sciences

Oxidative Stress–induced Antibodies to Carbonyl-modified Protein Correlate with Severity of Chronic Obstructive Pulmonary Disease

(2011) Paul A. Kirkham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Nortriptyline Reverses Corticosteroid Insensitivity by Inhibition of Phosphoinositide-3-Kinase- 

(2011) N. Mercado et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Anti-Tissue Antibodies Are Related to Lung Function in Chronic Obstructive Pulmonary Disease

(2010) Belén Núñez et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Treatment Effects of Low-Dose Theophylline Combined With an Inhaled Corticosteroid in COPD

(2010) Paul A. Ford et al.   CHEST

What Is Autoimmunity and Why Is It Likely to Be Important in Chronic Lung Disease?

(2009) Steven R. Duncan   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inflammatory biomarkers in airways of patients with severe asthma compared with non-severe asthma

(2009) P. Macedo et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Glucocorticoid resistance in inflammatory diseases

(2009) Peter J Barnes et al.   LANCET

Suppression of GATA-3 Nuclear Import and Phosphorylation: A Novel Mechanism of Corticosteroid Action in Allergic Disease

(2009) Kittipong Maneechotesuwan et al.   PLOS MEDICINE

B Cell Development: Important Work for ERK

(2008) Michael R. Gold   IMMUNITY