Corticosteroid Resistance and Novel Anti-Inflammatory Therapies in Chronic Obstructive Pulmonary Disease

Current Controversies and Future Perspectives in Chronic Obstructive Pulmonary Disease

(2011) Alvar Agustí et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease

(2011) Omar S. Usmani et al.   ANNALS OF MEDICINE

p38 Mitogen-Activated Protein Kinase Pathways in Asthma and COPD

(2011) Kian Fan Chung   CHEST

An Oral Inhibitor of p38 MAP Kinase Reduces Plasma Fibrinogen in Patients With Chronic Obstructive Pulmonary Disease

(2011) David A. Lomas et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Ligand-Independent Phosphorylation of the Glucocorticoid Receptor Integrates Cellular Stress Pathways with Nuclear Receptor Signaling

(2011) A. J. Galliher-Beckley et al.   MOLECULAR AND CELLULAR BIOLOGY

Targeting Phosphoinositide-3-Kinase-δ with Theophylline Reverses Corticosteroid Insensitivity in Chronic Obstructive Pulmonary Disease

(2010) Yasuo To et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Glucocorticosteroids: current and future directions

(2010) Peter J Barnes   BRITISH JOURNAL OF PHARMACOLOGY

Lung Deposition of BDP/Formoterol HFA pMDI in Healthy Volunteers, Asthmatic, and COPD Patients

(2010) Wilfried De Backer et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

New Therapies for Chronic Obstructive Pulmonary Disease

(2010) Peter J. Barnes   MEDICAL PRINCIPLES AND PRACTICE

Inhaled Corticosteroids in COPD: A Controversy

(2010) Peter J. Barnes   RESPIRATION

Inhibition of PI3Kδ Restores Glucocorticoid Function in Smoking-induced Airway Inflammation in Mice

(2009) John A. Marwick et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Dual PDE3/4 inhibitors as therapeutic agents for chronic obstructive pulmonary disease

(2009) Katharine H Banner et al.   BRITISH JOURNAL OF PHARMACOLOGY

Effect of low-dose theophylline plus beclometasone on lung function in smokers with asthma: a pilot study

(2009) M. Spears et al.   EUROPEAN RESPIRATORY JOURNAL

Inhaled corticosteroids in COPD: the case against

(2009) S. Suissa et al.   EUROPEAN RESPIRATORY JOURNAL

Phosphoinositide 3-kinase   required for lipopolysaccharide-induced transepithelial neutrophil trafficking in the lung

(2009) J. Reutershan et al.   EUROPEAN RESPIRATORY JOURNAL

Pneumonia risk in COPD patients receiving inhaled corticosteroids alone or in combination: TORCH study results

(2009) C. Crim et al.   EUROPEAN RESPIRATORY JOURNAL

Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials

(2009) Leonardo M Fabbri et al.   LANCET

Cluster Analysis and Clinical Asthma Phenotypes

(2008) Pranab Haldar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Effect of Pharmacotherapy on Rate of Decline of Lung Function in Chronic Obstructive Pulmonary Disease

(2008) Bartolomé R. Celli et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

SIRT1, an Antiinflammatory and Antiaging Protein, Is Decreased in Lungs of Patients with Chronic Obstructive Pulmonary Disease

(2008) Saravanan Rajendrasozhan et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Can the anti-inflammatory potential of PDE4 inhibitors be realized: guarded optimism or wishful thinking?

(2008) M A Giembycz   BRITISH JOURNAL OF PHARMACOLOGY

Emerging Pharmacotherapies for COPD

(2008) Peter J. Barnes   CHEST

Influence of smoking on airway inflammation and remodelling in asthma

(2008) J. St-Laurent et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Methodological issues in therapeutic trials of COPD

(2008) S. Suissa et al.   EUROPEAN RESPIRATORY JOURNAL

Aerosolized Phosphoinositide 3-Kinase  /  Inhibitor TG100-115 [3-[2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease

(2008) J. Doukas et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Targeting Nrf2 with the triterpenoid CDDO- imidazolide attenuates cigarette smoke-induced emphysema and cardiac dysfunction in mice

(2008) T. E. Sussan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CXCR3 and CCR5 Chemokines in Induced Sputum From Patients With COPD

(2007) Claudia Costa et al.   CHEST

Increased activation of p38 MAPK in COPD

(2007) T. Renda et al.   EUROPEAN RESPIRATORY JOURNAL