Loss of expression of protein phosphatase magnesium-dependent 1A during kidney injury promotes fibrotic maladaptive repair

Tumor suppressor ataxia telangiectasia mutated functions downstream of TGF-β1 in orchestrating profibrotic responses

(2015) Jessica M. Overstreet et al.   FASEB JOURNAL

Loss of tumour suppressor PTEN expression in renal injury initiates SMAD3- and p53-dependent fibrotic responses

(2015) Rohan Samarakoon et al.   JOURNAL OF PATHOLOGY

Protein Phosphatase Magnesium Dependent 1A Governs the Wound Healing–Inflammation–Angiogenesis Cross Talk on Injury

(2014) Zeev Dvashi et al.   AMERICAN JOURNAL OF PATHOLOGY

Redox control of p53 in the transcriptional regulation of TGF-β1 target genes through SMAD cooperativity

(2014) Jessica M. Overstreet et al.   CELLULAR SIGNALLING

A perspective on anti-CCN2 therapy for chronic kidney disease

(2014) L. L. Falke et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

The Epidemiology, Diagnosis, and Management of Aristolochic Acid Nephropathy

(2013) M. Refik Gökmen et al.   ANNALS OF INTERNAL MEDICINE

Induction of renal fibrotic genes by TGF-β1 requires EGFR activation, p53 and reactive oxygen species

(2013) Rohan Samarakoon et al.   CELLULAR SIGNALLING

Chronic kidney disease: global dimension and perspectives

(2013) Vivekanand Jha et al.   LANCET

Transforming growth factor-  and the progression of renal disease

(2013) I. Loeffler et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Therapy for Fibrotic Diseases: Nearing the Starting Line

(2013) S. L. Friedman et al.   Science Translational Medicine

Host Responses in Tissue Repair and Fibrosis

(2012) Jeremy S. Duffield et al.   Annual Review of Pathology-Mechanisms of Disease

TGF-β signaling in tissue fibrosis: Redox controls, target genes and therapeutic opportunities

(2012) Rohan Samarakoon et al.   CELLULAR SIGNALLING

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Chronic kidney disease: a research and public health priority

(2012) N. Perico et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Loss of Endogenous Bone Morphogenetic Protein-6 Aggravates Renal Fibrosis

(2011) Amélie Dendooven et al.   AMERICAN JOURNAL OF PATHOLOGY

TGF-β1 → SMAD/p53/USF2 → PAI-1 transcriptional axis in ureteral obstruction-induced renal fibrosis

(2011) Rohan Samarakoon et al.   CELL AND TISSUE RESEARCH

Delayed Re-epithelialization in Ppm1a Gene-deficient Mice Is Mediated by Enhanced Activation of Smad2

(2011) Xue Yang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The contribution of chronic kidney disease to the global burden of major noncommunicable diseases

(2011) William G. Couser et al.   KIDNEY INTERNATIONAL

Redox-Induced Src Kinase and Caveolin-1 Signaling in TGF-β1-Initiated SMAD2/3 Activation and PAI-1 Expression

(2011) Rohan Samarakoon et al.   PLoS One

Epithelial cell cycle arrest in G2/M mediates kidney fibrosis after injury

(2010) Li Yang et al.   NATURE MEDICINE

Renal fibrosis: novel insights into mechanisms and therapeutic targets

(2010) Peter Boor et al.   Nature Reviews Nephrology

Ureteral obstruction as a model of renal interstitial fibrosis and obstructive nephropathy

(2009) Robert L. Chevalier et al.   KIDNEY INTERNATIONAL

Opposite Effects of Dihydrosphingosine 1-Phosphate and Sphingosine 1-Phosphate on Transforming Growth Factor-β/Smad Signaling Are Mediated through the PTEN/PPM1A-dependent Pathway

(2008) Shizhong Bu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY