Histone crotonylation regulates neural stem cell fate decisions by activating bivalent promoters

Histone crotonylation promotes mesoendodermal commitment of human embryonic stem cells

(2021) Yi Fang et al.   Cell Stem Cell

Short-Chain Enoyl-CoA Hydratase Mediates Histone Crotonylation and Contributes to Cardiac Homeostasis

(2021) Xiaoqiang Tang et al.   CIRCULATION

Metabolism and the Epigenome: A Dynamic Relationship

(2020) Spencer A. Haws et al.   TRENDS IN BIOCHEMICAL SCIENCES

Single-cell transcriptomic analysis of mouse neocortical development

(2019) Lipin Loo et al.   Nature Communications

HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development

(2019) Tianxiang Tang et al.   NEURON

The DNA modification N6-methyl-2’-deoxyadenosine (m6dA) drives activity-induced gene expression and is required for fear extinction

(2019) Xiang Li et al.   NATURE NEUROSCIENCE

Acetylation & Co: an expanding repertoire of histone acylations regulates chromatin and transcription

(2019) Claire E. Barnes et al.   Essays in Biochemistry

NEAT1 regulates neuroglial cell mediating Aβ clearance via the epigenetic regulation of endocytosis-related genes expression

(2019) Ziqiang Wang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The nucleosome: from structure to function through physics

(2019) Alexey V Onufriev et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

CUT&Tag for efficient epigenomic profiling of small samples and single cells

(2019) Hatice S. Kaya-Okur et al.   Nature Communications

Gcn5 and Esa1 function as histone crotonyltransferases to regulate crotonylation-dependent transcription

(2019) Leonie Kollenstart et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Recognition of Histone Crotonylation by Taf14 Links Metabolic State to Gene Expression

(2019) Graeme J. Gowans et al.   MOLECULAR CELL

Dietary Micronutrients Promote Neuronal Differentiation by Modulating the Mitochondrial-Nuclear Dialogue

(2018) Kui Xie et al.   BIOESSAYS

HIV latency is reversed by ACSS2-driven histone crotonylation

(2018) Guochun Jiang et al.   JOURNAL OF CLINICAL INVESTIGATION

Integrating single-cell transcriptomic data across different conditions, technologies, and species

(2018) Andrew Butler et al.   NATURE BIOTECHNOLOGY

Regulation of chromatin and gene expression by metabolic enzymes and metabolites

(2018) Xinjian Li et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microbiota derived short chain fatty acids promote histone crotonylation in the colon through histone deacetylases

(2018) Rachel Fellows et al.   Nature Communications

Histone deacetylase (HDAC) 1 and 2 complexes regulate both histone acetylation and crotonylation in vivo

(2018) R. D. W. Kelly et al.   Scientific Reports

Chromodomain Y-like Protein–Mediated Histone Crotonylation Regulates Stress-Induced Depressive Behaviors

(2018) Yongqing Liu et al.   BIOLOGICAL PSYCHIATRY

HDAC1 and HDAC3 underlie dynamic H3K9 acetylation during embryonic neurogenesis and in schizophrenia-like animals

(2017) Josef Večeřa et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Large-Scale Identification of Protein Crotonylation Reveals Its Role in Multiple Cellular Functions

(2017) Wei Wei et al.   JOURNAL OF PROTEOME RESEARCH

Chromodomain Protein CDYL Acts as a Crotonyl-CoA Hydratase to Regulate Histone Crotonylation and Spermatogenesis

(2017) Shumeng Liu et al.   MOLECULAR CELL

Salmon provides fast and bias-aware quantification of transcript expression

(2017) Rob Patro et al.   NATURE METHODS

MiR-203 Interplays with Polycomb Repressive Complexes to Regulate the Proliferation of Neural Stem/Progenitor Cells

(2017) Pei-Pei Liu et al.   Stem Cell Reports

MOF as an evolutionarily conserved histone crotonyltransferase and transcriptional activation by histone acetyltransferase-deficient and crotonyltransferase-competent CBP/p300

(2017) Xiaoguang Liu et al.   Cell Discovery

YEATS2 is a selective histone crotonylation reader

(2016) Dan Zhao et al.   CELL RESEARCH

Molecular Coupling of Histone Crotonylation and Active Transcription by AF9 YEATS Domain

(2016) Yuanyuan Li et al.   MOLECULAR CELL

Selective recognition of histone crotonylation by double PHD fingers of MOZ and DPF2

(2016) Xiaozhe Xiong et al.   Nature Chemical Biology

The Taf14 YEATS domain is a reader of histone crotonylation

(2016) Forest H Andrews et al.   Nature Chemical Biology

Metabolic regulation of gene expression through histone acylations

(2016) Benjamin R. Sabari et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

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Lateral Thinking: How Histone Modifications Regulate Gene Expression

(2016) Moyra Lawrence et al.   TRENDS IN GENETICS

ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization

(2015) Guangchuang Yu et al.   BIOINFORMATICS

Glycolysis-Mediated Changes in Acetyl-CoA and Histone Acetylation Control the Early Differentiation of Embryonic Stem Cells

(2015) Arieh Moussaieff et al.   Cell Metabolism

Intracellular Crotonyl-CoA Stimulates Transcription through p300-Catalyzed Histone Crotonylation

(2015) Benjamin R. Sabari et al.   MOLECULAR CELL

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(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders

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The emerging roles of TCF4 in disease and development

(2014) Marc P. Forrest et al.   TRENDS IN MOLECULAR MEDICINE

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(2013) Su Wang et al.   Nature Protocols

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(2013) Gabriel E Zentner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

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ChromHMM: automating chromatin-state discovery and characterization

(2012) Jason Ernst et al.   NATURE METHODS

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(2012) Ben Langmead et al.   NATURE METHODS

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(2012) Jianxing Feng et al.   Nature Protocols

clusterProfiler: an R Package for Comparing Biological Themes Among Gene Clusters

(2012) Guangchuang Yu et al.   OMICS-A JOURNAL OF INTEGRATIVE BIOLOGY

Identification of Combinatorial Patterns of Post-Translational Modifications on Individual Histones in the Mouse Brain

(2012) Ry Y. Tweedie-Cullen et al.   PLoS One

MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets

(2012) Zhen Shao et al.   GENOME BIOLOGY

Bismark: a flexible aligner and methylation caller for Bisulfite-Seq applications

(2011) Felix Krueger et al.   BIOINFORMATICS

Identification of 67 Histone Marks and Histone Lysine Crotonylation as a New Type of Histone Modification

(2011) Minjia Tan et al.   CELL

BEDTools: a flexible suite of utilities for comparing genomic features

(2010) Aaron R. Quinlan et al.   BIOINFORMATICS

Epigenetic Regulation of miR-184 by MBD1 Governs Neural Stem Cell Proliferation and Differentiation

(2010) Changmei Liu et al.   Cell Stem Cell

CBP Histone Acetyltransferase Activity Regulates Embryonic Neural Differentiation in the Normal and Rubinstein-Taybi Syndrome Brain

(2010) Jing Wang et al.   DEVELOPMENTAL CELL

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

SOX9 induces and maintains neural stem cells

(2010) Charlotte E Scott et al.   NATURE NEUROSCIENCE

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Genome-wide Mapping of HATs and HDACs Reveals Distinct Functions in Active and Inactive Genes

(2009) Zhibin Wang et al.   CELL