Targeting prominin2 transcription to overcome ferroptosis resistance in cancer

Prominin2 Drives Ferroptosis Resistance by Stimulating Iron Export

(2019) Caitlin W. Brown et al.   DEVELOPMENTAL CELL

Inhibiting Heat Shock Factor 1 in Cancer: A Unique Therapeutic Opportunity

(2019) Bushu Dong et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Low-density lipoprotein docosahexaenoic acid nanoparticles induce ferroptotic cell death in hepatocellular carcinoma

(2017) Weijun Ou et al.   FREE RADICAL BIOLOGY AND MEDICINE

The α6β4 integrin promotes resistance to ferroptosis

(2017) Caitlin W. Brown et al.   JOURNAL OF CELL BIOLOGY

Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition

(2017) Matthew J. Hangauer et al.   NATURE

Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway

(2017) Vasanthi S. Viswanathan et al.   NATURE

Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis

(2016) Kenichi Shimada et al.   Nature Chemical Biology

Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis

(2016) Wan Seok Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

HSPB1 as a novel regulator of ferroptotic cancer cell death

(2015) X Sun et al.   ONCOGENE

Coniferyl Aldehyde Attenuates Radiation Enteropathy by Inhibiting Cell Death and Promoting Endothelial Cell Function

(2015) Ye-Ji Jeong et al.   PLoS One

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

The generation of 4-hydroxynonenal, an electrophilic lipid peroxidation end product, in rabbit cornea organ cultures treated with UVB light and nitrogen mustard

(2013) Ruijin Zheng et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Overview of lipid peroxidation products and hepatic protein modification in alcoholic liver disease

(2011) Rebecca L. Smathers et al.   CHEMICO-BIOLOGICAL INTERACTIONS

KRIBB11 Inhibits HSP70 Synthesis through Inhibition of Heat Shock Factor 1 Function by Impairing the Recruitment of Positive Transcription Elongation Factor b to thehsp70Promoter

(2010) Young Ju Yoon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Human Breast Cell Model of Preinvasive to Invasive Transition

(2008) A. Rizki et al.   CANCER RESEARCH

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Synthetic Lethal Screening Identifies Compounds Activating Iron-Dependent, Nonapoptotic Cell Death in Oncogenic-RAS-Harboring Cancer Cells

(2008) Wan Seok Yang et al.   CHEMISTRY & BIOLOGY

Global Analysis of Protein Damage by the Lipid Electrophile 4-Hydroxy-2-nonenal

(2008) Simona G. Codreanu et al.   MOLECULAR & CELLULAR PROTEOMICS