The impact of microRNA gene regulation on the survival and function of mature cell types in the eye

Single-Molecule Imaging Reveals that Argonaute Reshapes the Binding Properties of Its Nucleic Acid Guides

(2015) William E. Salomon et al.   CELL

A Dynamic Search Process Underlies MicroRNA Targeting

(2015) Stanley D. Chandradoss et al.   CELL

MicroRNAs are essential for differentiation of the retinal pigmented epithelium and maturation of adjacent photoreceptors

(2015) R. Ohana et al.   DEVELOPMENT

Human Argonaute 2 Has Diverse Reaction Pathways on Target RNAs

(2015) Myung Hyun Jo et al.   MOLECULAR CELL

MicroRNA-mediated mechanisms of the cellular stress response in atherosclerosis

(2015) Andreas Schober et al.   Nature Reviews Cardiology

MiR-204 is responsible for inherited retinal dystrophy associated with ocular coloboma

(2015) Ivan Conte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The biological functions of miRNAs: lessons from in vivo studies

(2015) Joana A. Vidigal et al.   TRENDS IN CELL BIOLOGY

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture

(2015) Jacek Krol et al.   Nature Communications

Iron Toxicity in the Retina Requires Alu RNA and the NLRP3 Inflammasome

(2015) Bradley D. Gelfand et al.   Cell Reports

Altered miRNA expression in canine retinas during normal development and in models of retinal degeneration

(2014) Sem Genini et al.   BMC GENOMICS

MicroRNAs and their roles in developmental canalization

(2014) Diana M Posadas et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

DICER1 is essential for survival of postmitotic rod photoreceptor cells in mice

(2014) Thomas R. Sundermeier et al.   FASEB JOURNAL

miR-184 regulates ezrin, LAMP-1 expression, affects phagocytosis in human retinal pigment epithelium and is downregulated in age-related macular degeneration

(2014) Najiba Murad et al.   FEBS Journal

BDNF Promotes Axon Branching of Retinal Ganglion Cells via miRNA-132 and p250GAP

(2014) Katharine J. Marler et al.   JOURNAL OF NEUROSCIENCE

miRNAs 182 and 183 Are Necessary to Maintain Adult Cone Photoreceptor Outer Segments and Visual Function

(2014) Volker Busskamp et al.   NEURON

The combination of transcriptomics and informatics identifies pathways targeted by miR-204 during neurogenesis and axon guidance

(2014) Ivan Conte et al.   NUCLEIC ACIDS RESEARCH

DICER1/AluRNA dysmetabolism induces Caspase-8–mediated cell death in age-related macular degeneration

(2014) Younghee Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systems pharmacology identifies drug targets for Stargardt disease–associated retinal degeneration

(2013) Yu Chen et al.   JOURNAL OF CLINICAL INVESTIGATION

Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration

(2013) S. Lumayag et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pax6 Regulates Gene Expression in the Vertebrate Lens through miR-204

(2013) Ohad Shaham et al.   PLoS Genetics

Roles for MicroRNAs in Conferring Robustness to Biological Processes

(2012) Margaret S. Ebert et al.   CELL

DICER1 Loss and Alu RNA Induce Age-Related Macular Degeneration via the NLRP3 Inflammasome and MyD88

(2012) Valeria Tarallo et al.   CELL

Microphthalmia-associated Transcription Factor (MITF) Promotes Differentiation of Human Retinal Pigment Epithelium (RPE) by Regulating microRNAs-204/211 Expression

(2012) Jeffrey Adijanto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Argonaute CLIP – A method to identify in vivo targets of miRNAs

(2012) Lukasz Jaskiewicz et al.   METHODS

Genome-wide identification of miRNA targets by PAR-CLIP

(2012) Markus Hafner et al.   METHODS

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

DICER- and AGO3-dependent generation of retinoic acid–induced DR2 Alu RNAs regulates human stem cell proliferation

(2012) QiDong Hu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

ERK1/2 activation is a therapeutic target in age-related macular degeneration

(2012) S. Dridi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Resource for the Conditional Ablation of microRNAs in the Mouse

(2012) Chong Yon Park et al.   Cell Reports

miRNeye: a microRNA expression atlas of the mouse eye

(2011) Marianthi Karali et al.   BMC GENOMICS

Dicer is required for the maintenance of notch signaling and gliogenic competence during mouse retinal development

(2011) Sean A. Georgi et al.   Developmental Neurobiology

Sponge Transgenic Mouse Model Reveals Important Roles for the MicroRNA-183 (miR-183)/96/182 Cluster in Postmitotic Photoreceptors of the Retina

(2011) Qubo Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

DICER1 deficit induces Alu RNA toxicity in age-related macular degeneration

(2011) Hiroki Kaneko et al.   NATURE

A resource of vectors and ES cells for targeted deletion of microRNAs in mice

(2011) Haydn M Prosser et al.   NATURE BIOTECHNOLOGY

miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

(2011) Rikako Sanuki et al.   NATURE NEUROSCIENCE

miR-96 regulates the progression of differentiation in mammalian cochlear inner and outer hair cells

(2011) S. Kuhn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway

(2010) R. Krishnan Kutty et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Characterizing Light-Regulated Retinal MicroRNAs Reveals Rapid Turnover as a Common Property of Neuronal MicroRNAs

(2010) Jacek Krol et al.   CELL

Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium

(2010) N. Davis et al.   DEVELOPMENT

MicroRNA-204/211 alters epithelial physiology

(2010) Fei E. Wang et al.   FASEB JOURNAL

Dynamic Changes of microRNAs in the Eye during the Development of Experimental Autoimmune Uveoretinitis

(2010) W. Ishida et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Dicer Is Required for the Transition from Early to Late Progenitor State in the Developing Mouse Retina

(2010) S. A. Georgi et al.   JOURNAL OF NEUROSCIENCE

MicroRNA Functions in Stress Responses

(2010) Anthony K.L. Leung et al.   MOLECULAR CELL

miR-204 is required for lens and retinal development via Meis2 targeting

(2010) I. Conte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A MicroRNA Imparts Robustness against Environmental Fluctuation during Development

(2009) Xin Li et al.   CELL

microRNA-24a is required to repress apoptosis in the developing neural retina

(2009) J. C. Walker et al.   GENES & DEVELOPMENT

Argonaute HITS-CLIP decodes microRNA–mRNA interaction maps

(2009) Sung Wook Chi et al.   NATURE

Changes in expression of sensory organ-specific microRNAs in rat dorsal root ganglia in association with mechanical hypersensitivity induced by spinal nerve ligation

(2009) B.T. Aldrich et al.   NEUROSCIENCE

MicroRNAs couple cell fate and developmental timing in retina

(2009) Sarah Decembrini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A common microRNA signature in mouse models of retinal degeneration

(2008) Carol J. Loscher et al.   EXPERIMENTAL EYE RESEARCH

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Dicer inactivation causes heterochronic retinogenesis in Xenopus laevis

(2008) Sarah Decembrini et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Dicer Inactivation Leads to Progressive Functional and Structural Degeneration of the Mouse Retina

(2008) D. Damiani et al.   JOURNAL OF NEUROSCIENCE

MicroRNAs Regulate Ocular Neovascularization

(2008) JiKui Shen et al.   MOLECULAR THERAPY

Molecular characterization of human Argonaute-containing ribonucleoprotein complexes and their bound target mRNAs

(2008) M. Landthaler et al.   RNA