Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation

Metabolic Signatures of Distinct Endothelial Phenotypes

(2020) Sébastien J. Dumas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Solo: Doublet Identification in Single-Cell RNA-Seq via Semi-Supervised Deep Learning

(2020) Nicholas J. Bernstein et al.   Cell Systems

Wnt signaling activates MFSD2A to suppress vascular endothelial transcytosis and maintain blood-retinal barrier

(2020) Zhongxiao Wang et al.   Science Advances

Single-Cell Analysis of Blood-Brain Barrier Response to Pericyte Loss

(2020) Maarja Andaloussi Mäe et al.   CIRCULATION RESEARCH

Comprehensive Integration of Single-Cell Data

(2019) Tim Stuart et al.   CELL

Cholinergic neural activity directs retinal layer-specific angiogenesis and blood retinal barrier formation

(2019) G. A. Weiner et al.   Nature Communications

Vascular deficiency of Smad4 causes arteriovenous malformations: a mouse model of Hereditary Hemorrhagic Telangiectasia

(2018) Angela M. Crist et al.   ANGIOGENESIS

Single-Cell Transcriptome Analyses Reveal Endothelial Cell Heterogeneity in Tumors and Changes following Antiangiogenic Treatment

(2018) Qi Zhao et al.   CANCER RESEARCH

SMAD4 Prevents Flow Induced Arterial-Venous Malformations by Inhibiting Casein Kinase 2

(2018) Roxana Ola et al.   CIRCULATION

Genetic Targeting of Organ-Specific Blood VesselsNovelty and Significance

(2018) Wenjuan Pu et al.   CIRCULATION RESEARCH

NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy

(2018) Alexandre Dubrac et al.   Nature Communications

Light Prior to Eye Opening Promotes Retinal Waves and Eye-Specific Segregation

(2018) Alexandre Tiriac et al.   NEURON

Vascular heterogeneity and specialization in development and disease

(2017) Michael Potente et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Wnt Inhibitor Apcdd1 Coordinates Vascular Remodeling and Barrier Maturation of Retinal Blood Vessels

(2017) Jenna Mazzoni et al.   NEURON

Blood-Brain Barrier Permeability Is Regulated by Lipid Transport-Dependent Suppression of Caveolae-Mediated Transcytosis

(2017) Benjamin J. Andreone et al.   NEURON

Gradual Suppression of Transcytosis Governs Functional Blood-Retinal Barrier Formation

(2017) Brian Wai Chow et al.   NEURON

Organotypic vasculature: From descriptive heterogeneity to functional pathophysiology

(2017) Hellmut G. Augustin et al.   SCIENCE

Transcriptional regulation of endothelial cell behavior during sprouting angiogenesis

(2017) Hyun-Woo Jeong et al.   Nature Communications

Plastic roles of pericytes in the blood–retinal barrier

(2017) Do Young Park et al.   Nature Communications

Pericytes regulate VEGF-induced endothelial sprouting through VEGFR1

(2017) Hanna M. Eilken et al.   Nature Communications

Non-Smad Signaling Pathways of the TGF-β Family

(2016) Ying E. Zhang   Cold Spring Harbor Perspectives in Biology

PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia

(2016) Roxana Ola et al.   Nature Communications

Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets

(2015) Evan Z. Macosko et al.   CELL

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

(2015) Sandra Schoors et al.   NATURE

Alk1 and Alk5 inhibition by Nrp1 controls vascular sprouting downstream of Notch

(2015) Irene Maria Aspalter et al.   Nature Communications

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Esm1 Modulates Endothelial Tip Cell Behavior and Vascular Permeability by Enhancing VEGF Bioavailability

(2014) Susana F. Rocha et al.   CIRCULATION RESEARCH

Familial exudative vitreoretinopathy and related retinopathies

(2014) D F Gilmour   EYE

Mfsd2a is critical for the formation and function of the blood–brain barrier

(2014) Ayal Ben-Zvi et al.   NATURE

Endothelial Depletion of Acvrl1 in Mice Leads to Arteriovenous Malformations Associated with Reduced Endoglin Expression

(2014) Simon Tual-Chalot et al.   PLoS One

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

(2013) Katrien De Bock et al.   CELL

The mouse retina in 3D: quantification of vascular growth and remodeling

(2013) Florian Milde et al.   Integrative Biology

VEGF and Notch in Tip and Stalk Cell Selection

(2013) R. Blanco et al.   Cold Spring Harbor Perspectives in Medicine

Defective Retinal Vascular Endothelial Cell Development As a Consequence of Impaired Integrin  V 8-Mediated Activation of Transforming Growth Factor- 

(2012) T. D. Arnold et al.   JOURNAL OF NEUROSCIENCE

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Targeting the TGFβ signalling pathway in disease

(2012) Rosemary J. Akhurst et al.   NATURE REVIEWS DRUG DISCOVERY

TGFβ signalling in context

(2012) Joan Massagué   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Vascular Endothelial Growth Factor A in Intraocular Vascular Disease

(2012) Joan W. Miller et al.   OPHTHALMOLOGY

Retinal Expression of Wnt-Pathway Mediated Genes in Low-Density Lipoprotein Receptor-Related Protein 5 (Lrp5) Knockout Mice

(2012) Jing Chen et al.   PLoS One

Endothelial Expression of TGFβ Type II Receptor Is Required to Maintain Vascular Integrity during Postnatal Development of the Central Nervous System

(2012) Kathleen R. Allinson et al.   PLoS One

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

Basic and Therapeutic Aspects of Angiogenesis

(2011) Michael Potente et al.   CELL

The astrocyte-expressed integrin  v 8 governs blood vessel sprouting in the developing retina

(2011) S. Hirota et al.   DEVELOPMENT

Coordinating cell behaviour during blood vessel formation

(2011) I. Geudens et al.   DEVELOPMENT

Pericytes: Developmental, Physiological, and Pathological Perspectives, Problems, and Promises

(2011) Annika Armulik et al.   DEVELOPMENTAL CELL

Microarray analysis of retinal endothelial tip cells identifies CXCR4 as a mediator of tip cell morphology and branching

(2010) G. A. Strasser et al.   BLOOD

Identification and functional analysis of endothelial tip cell-enriched genes

(2010) R. del Toro et al.   BLOOD

Special features of human retinal angiogenesis

(2010) R F Gariano   EYE

Retinopathy of prematurity: understanding ischemic retinal vasculopathies at an extreme of life

(2010) Przemyslaw Sapieha et al.   JOURNAL OF CLINICAL INVESTIGATION

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis

(2010) Yingdi Wang et al.   NATURE

Pericytes regulate the blood–brain barrier

(2010) Annika Armulik et al.   NATURE

Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting

(2010) Lars Jakobsson et al.   NATURE CELL BIOLOGY

Axon Guidance Molecules in Vascular Patterning

(2010) R. H. Adams et al.   Cold Spring Harbor Perspectives in Biology

TSPAN12 Regulates Retinal Vascular Development by Promoting Norrin- but Not Wnt-Induced FZD4/β-Catenin Signaling

(2009) Harald J. Junge et al.   CELL

Norrin, Frizzled-4, and Lrp5 Signaling in Endothelial Cells Controls a Genetic Program for Retinal Vascularization

(2009) Xin Ye et al.   CELL

A model for familial exudative vitreoretinopathy caused by LPR5 mutations

(2008) C.-H. Xia et al.   HUMAN MOLECULAR GENETICS

Redundant Roles of SMAD2 and SMAD3 in Ovarian Granulosa Cells In Vivo

(2008) Q. Li et al.   MOLECULAR AND CELLULAR BIOLOGY