Fis1 ablation in the male germline disrupts mitochondrial morphology and mitophagy, and arrests spermatid maturation

ATP activation of peritubular cells drives testicular sperm transport

(2021) David Fleck et al.   eLife

MFN2 interacts with Nuage-associated proteins and is essential for male germ cell development by controlling mRNA fate during spermatogenesis

(2021) Xiaoli Wang et al.   DEVELOPMENT

Function and regulation of the divisome for mitochondrial fission

(2021) Felix Kraus et al.   NATURE

Mitochondrial fission factor (Mff) is required for organization of the mitochondrial sheath in spermatids

(2021) Grigor Varuzhanyan et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Distinct fission signatures predict mitochondrial degradation or biogenesis

(2021) Tatjana Kleele et al.   NATURE

MFN2 Plays a Distinct Role from MFN1 in Regulating Spermatogonial Differentiation

(2020) Wei Chen et al.   Stem Cell Reports

Mitochondrial dynamics during spermatogenesis

(2020) Grigor Varuzhanyan et al.   JOURNAL OF CELL SCIENCE

Role of Selective Autophagy in Spermatogenesis and Male Fertility

(2020) Chunyu Lv et al.   Cells

STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism

(2019) Hongxu Xian et al.   Nature Communications

A defect in the peroxisomal biogenesis in germ cells induces a spermatogenic arrest at the round spermatid stage in mice

(2019) Ann-Kristin Brauns et al.   Scientific Reports

Fis1 deficiencies differentially affect mitochondrial quality in skeletal muscle

(2019) Zhe Zhang et al.   MITOCHONDRION

Mitochondrial fusion is required for spermatogonial differentiation and meiosis

(2019) Grigor Varuzhanyan et al.   eLife

A Conserved Requirement for Fbxo7 During Male Germ Cell Cytoplasmic Remodeling

(2019) Claudia C. Rathje et al.   Frontiers in Physiology

Genome-wide synthetic lethal CRISPR screen identifies FIS1 as a genetic interactor of ALS-linked C9ORF72

(2019) Noori Chai et al.   BRAIN RESEARCH

AMPK/FIS1-Mediated Mitophagy Is Required for Self-Renewal of Human AML Stem Cells

(2018) Shanshan Pei et al.   Cell Stem Cell

Mitophagy and Quality Control Mechanisms in Mitochondrial Maintenance

(2018) Sarah Pickles et al.   CURRENT BIOLOGY

Mitochondria–lysosome contacts regulate mitochondrial fission via RAB7 GTP hydrolysis

(2018) Yvette C. Wong et al.   NATURE

Endosomal Rab cycles regulate Parkin-mediated mitophagy

(2018) Koji Yamano et al.   eLife

Drp1/Fis1-mediated mitochondrial fragmentation leads to lysosomal dysfunction in cardiac models of Huntington's disease

(2018) A.U. Joshi et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

TSSK6 is required for γH2AX formation and the histone-to-protamine transition during spermiogenesis

(2017) Kula N. Jha et al.   JOURNAL OF CELL SCIENCE

The Enigmatic Role of C9ORF72 in Autophagy

(2017) Melissa Nassif et al.   Frontiers in Neuroscience

Autophagy regulates spermatid differentiation via degradation of PDLIM1

(2016) Yongliang Shang et al.   Autophagy

Atg9A trafficking through the recycling endosomes is required for autophagosome formation

(2016) Kenta Imai et al.   JOURNAL OF CELL SCIENCE

Cooperative and independent roles of the Drp1 adaptors Mff, MiD49 and MiD51 in mitochondrial fission

(2016) Laura D. Osellame et al.   JOURNAL OF CELL SCIENCE

Fis1 depletion in osteoarthritis impairs chondrocyte survival and peroxisomal and lysosomal function

(2016) Dongkyun Kim et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Spermatogenesis: The Commitment to Meiosis

(2016) Michael D. Griswold   PHYSIOLOGICAL REVIEWS

Elimination of paternal mitochondria in mouse embryos occurs through autophagic degradation dependent on PARKIN and MUL1

(2016) Rebecca Rojansky et al.   eLife

GASZ and mitofusin‐mediated mitochondrial functions are crucial for spermatogenesis

(2015) Jingjing Zhang et al.   EMBO REPORTS

Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling

(2015) R. M. Hobbs et al.   EMBO REPORTS

p62/SQSTM1 functions as a signaling hub and an autophagy adaptor

(2015) Yoshinori Katsuragi et al.   FEBS Journal

Atg7 is required for acrosome biogenesis during spermatogenesis in mice

(2014) Hongna Wang et al.   CELL RESEARCH

Optimized flow cytometry isolation of murine spermatocytes

(2014) Valeriya Gaysinskaya et al.   CYTOMETRY PART A

The acrosomal protein SP-10 (Acrv1) is an ideal marker for staging of the cycle of seminiferous epithelium in the mouse

(2014) Hari Prasad Osuru et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

Transcellular degradation of axonal mitochondria

(2014) Chung-ha O. Davis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy

(2014) Koji Yamano et al.   eLife

Fis1, Mff, MiD49, and MiD51 mediate Drp1 recruitment in mitochondrial fission

(2013) Oliver C. Losón et al.   MOLECULAR BIOLOGY OF THE CELL

Mutations in Fis1 disrupt orderly disposal of defective mitochondria

(2013) Qinfang Shen et al.   MOLECULAR BIOLOGY OF THE CELL

Mouse lines with photo-activatable mitochondria to study mitochondrial dynamics

(2012) Anh H. Pham et al.   GENESIS

Germ Cell Intercellular Bridges

(2011) M. P. Greenbaum et al.   Cold Spring Harbor Perspectives in Biology

Visualization of Mitochondrial Respiratory Function using Cytochrome C Oxidase / Succinate Dehydrogenase (COX/SDH) Double-labeling Histochemistry

(2011) Jaime M. Ross   Jove-Journal of Visualized Experiments

Multinucleated Spermatocytes and Spermatids in Human Seminiferous Tubules*

(2010) A.F. HOLSTEIN et al.   ANDROLOGIA

Formal Genesis of Giant Cells in the Germinal Epithelium in the Rat Thioglucose Model

(2010) F. NEUMANN et al.   ANDROLOGIA

Toxic effects of dexamethasone on mouse testicular germ cells

(2010) M. Orazizadeh et al.   ANDROLOGIA

RNF8-Dependent Histone Modifications Regulate Nucleosome Removal during Spermatogenesis

(2010) Lin-Yu Lu et al.   DEVELOPMENTAL CELL

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

(2010) Hidenori Otera et al.   JOURNAL OF CELL BIOLOGY

γH2AX: a sensitive molecular marker of DNA damage and repair

(2010) L-J Mah et al.   LEUKEMIA

Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo

(2010) Michael R. Elliott et al.   NATURE

Rab7: roles in membrane trafficking and disease

(2009) Ming Zhang et al.   BIOSCIENCE REPORTS

Cre recombinase activity specific to postnatal, premeiotic male germ cells in transgenic mice

(2008) Patricia I. Sadate-Ngatchou et al.   GENESIS

Correction for non-perpendicularity of beam and tilt axis in tomographic reconstructions with the IMOD package

(2008) D. N. MASTRONARDE   JOURNAL OF MICROSCOPY