Curcumin Alleviates Cerebral Ischemia-reperfusion Injury by Inhibiting NLRP1-dependent Neuronal Pyroptosis

The neuroprotective effects of curcumin are associated with the regulation of the reciprocal function between autophagy and HIF-1α in cerebral ischemia-reperfusion injury

(2019) Yang Hou et al.   Drug Design Development and Therapy

Hispidulin exhibits neuroprotective activities against cerebral ischemia reperfusion injury through suppressing NLRP3-mediated pyroptosis

(2019) Pengpeng An et al.   LIFE SCIENCES

Current Mechanistic Concepts in Ischemia and Reperfusion Injury

(2018) Meng-Yu Wu et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Curcumin Suppresses IL-1β Secretion and Prevents Inflammation through Inhibition of the NLRP3 Inflammasome

(2018) Haipeng Yin et al.   JOURNAL OF IMMUNOLOGY

Curcumin protects neural cells against ischemic injury in N2a cells and mouse brain with ischemic stroke

(2018) Cai-Jun Xie et al.   Brain and Behavior

NLRP3 Inflammasome Inhibitor Ameliorates Amyloid Pathology in a Mouse Model of Alzheimer’s Disease

(2017) Jun Yin et al.   MOLECULAR NEUROBIOLOGY

Prospective clinical study of rehabilitation interventions with multisensory interactive training in patients with cerebral infarction: study protocol for a randomised controlled trial

(2017) Wai Leung Ambrose Lo et al.   Trials

Curcumin Anti-Apoptotic Action in a Model of Intestinal Epithelial Inflammatory Damage

(2017) Claudia Loganes et al.   Nutrients

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

(2016) Lorenzo Sborgi et al.   EMBO JOURNAL

Nanocurcumin accords protection against acute hypobaric hypoxia induced lung injury in rats

(2016) Sarita Nehra et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Pore-forming activity and structural autoinhibition of the gasdermin family

(2016) Jingjin Ding et al.   NATURE

Curcumin alleviates oxidative stress and mitochondrial dysfunction in astrocytes

(2016) Amita Daverey et al.   NEUROSCIENCE

Early single Aspirin-triggered Lipoxin blocked morphine anti-nociception tolerance through inhibiting NALP1 inflammasome: Involvement of PI3k/Akt signaling pathway

(2015) Yu Tian et al.   BRAIN BEHAVIOR AND IMMUNITY

NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

(2015) Chen-Chen Tan et al.   Journal of Neuroinflammation

Curcumin inhibits autophagy and apoptosis in hypoxia/reoxygenation-induced myocytes

(2015) ZHOUQING HUANG et al.   Molecular Medicine Reports

An-Gong-Niu-Huang Wan protects against cerebral ischemia induced apoptosis in rats: Up-regulation of Bcl-2 and down-regulation of Bax and caspase-3

(2014) Guo-Hua Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Nod-Like Receptor Protein 1 Inflammasome Mediates Neuron Injury under High Glucose

(2013) Xian-Fang Meng et al.   MOLECULAR NEUROBIOLOGY

Intravenous immunoglobulin suppresses NLRP1 and NLRP3 inflammasome-mediated neuronal death in ischemic stroke

(2013) D Yang-Wei Fann et al.   Cell Death & Disease

Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

(2012) F. Langhauser et al.   BLOOD

NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice

(2012) M. Kovarova et al.   JOURNAL OF IMMUNOLOGY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

Oxidative stress in ischaemic stroke

(2011) Laura Nanetti et al.   EUROPEAN JOURNAL OF CLINICAL INVESTIGATION

Lipoxin A 4 analogue protects brain and reduces inflammation in a rat model of focal cerebral ischemia reperfusion

(2010) Xi-Hong Ye et al.   BRAIN RESEARCH

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Inflammatory mechanisms in ischemic stroke: role of inflammatory cells

(2010) Rong Jin et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome

(2010) E. A. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms

(2008) S. L. Fink et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA