Article
Chemistry, Multidisciplinary
Guillaume Lefebvre, Antoine Maze, Rosa Alvarez-Palencia Jimenez, Franz Bruckert, Vasco Filipe, Sylvain Huille, Marianne Weidenhaupt
Summary: This study investigates the impact of plastic material surface properties on surfactant and monoclonal antibody adsorption. Results show that Polysorbate 80 provides significantly better protection against monoclonal antibody adsorption on polystyrene surfaces compared to hexadecane self-assembled monolayers, with protection efficacy depending on the concentration of surfactants and antibodies. The nature of plastic polymer surfaces affects surfactant adsorption and influences their protection efficacy in therapeutic antibody formulations, beyond just hydrophobicity.
PHARMACEUTICAL RESEARCH
(2021)
Article
Chemistry, Physical
I. M. Tucker, A. Burley, R. E. Petkova, S. L. Hosking, J. R. P. Webster, P. X. Li, K. Ma, J. Penfold, R. K. Thomas
Summary: Saponins are highly surface active glycosides that are extensively used in various industries. Although their adsorption at air-solution and liquid-liquid interfaces has been studied, their adsorption at solid surfaces is not well understood. This study aimed to investigate the adsorption of saponins at hydrophilic and hydrophobic solid surfaces. Neutron reflectivity was used to measure the adsorption at different concentrations of escin, quillaja, and glycyrrhizic acid. The results showed that there was no significant adsorption of saponins at either the hydrophilic or hydrophobic surface, indicating an inherent incompatibility between the saponin groups and the surface OH- groups. However, above a critical composition or concentration, adsorption was observed at the hydrophilic surface, with the adsorbed layer dominated by escin. This study provides valuable insights into the cooperative adsorption of saponins at solid-solution interfaces.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2024)
Article
Environmental Sciences
Jeison Manuel Arroyave, Marcelo Avena, Wenfeng Tan, Mingxia Wang
Summary: This article investigates the adsorption-desorption kinetics of phosphate on goethite using ATR-FTIR spectroscopy, providing new insights and experimental methods for understanding the behavior of pollutants with phosphonic or phosphinic moieties in the environment.
Article
Pharmacology & Pharmacy
Deepa Raghu, Pamela Hamill, Arpitha Banaji, Amy McLaren, Yu-Ting Hsu
Summary: Severe acute respiratory syndrome-associated coronavirus 2 (SARS-CoV-2) is a global health issue and the emergence of spike protein mutations may affect its binding to host cells and the effectiveness of neutralizing antibodies. This study investigated the binding activities of spike protein variants and their interactions with the ACE2 receptor, monoclonal antibodies, and the original spike protein receptor binding domain (RBD) sequence. The findings showed that certain mutants had increased binding affinity to ACE2, while others had reduced affinity. The neutralizing capability of monoclonal antibodies was also assessed, with one antibody showing partial blocking for a specific mutant.
JOURNAL OF PHARMACEUTICAL ANALYSIS
(2022)
Article
Chemistry, Multidisciplinary
Dirk J. Groenendijk, Johannes N. M. van Wunnik
Summary: The monomer-micelle equilibrium leads to an asymmetry between surfactant adsorption and desorption rates. Adsorption of monomers to the surface is favored over micelle formation, resulting in slow desorption rates limited by the critical micelle concentration.
Article
Biophysics
Yu Chen, Yaofei Chen, Weicheng Shi, Shiqi Hu, Qizhang Huang, Gui-Shi Liu, Jifu Shi, Lei Chen, Nur Hidayah Azeman, Ahmad Ashrif A. Bakar, Yunhan Luo, Zhe Chen
Summary: Combining SPR sensors with MoS2 nanoflowers can enhance the adsorption and desorption efficiency of amino acids, enabling controllable detection of amino acids. By adjusting the solution pH, precise detection of amino acids can be achieved.
BIOSENSORS & BIOELECTRONICS
(2022)
Article
Chemistry, Multidisciplinary
Chenxu Liu, Yu Tian, Yonggang Meng
Summary: Triboelectrochemical reactions occur on solid-liquid interfaces when a strong enough electric field and sufficient frictional stress are simultaneously imposed. These reactions are influenced not only by thermal energy, but also by electrical and mechanical energies, which in turn affect the properties of the interfaces.
FRONTIERS IN CHEMISTRY
(2021)
Article
Chemistry, Physical
Liang Xiao Gan, Chun Ling Hao, Xiao Ming Jiang
Summary: The study focused on using cucurbituril (Q[7]) to modulate the adsorption and desorption of cationic surfactants on quartz surfaces.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Biochemistry & Molecular Biology
Alan Stampini Benhame de Castro, Hauster Maximiler Campos de Paula, Yara Luiza Coelho, Eliara Acipreste Hudson, Ana Clarissa S. Pires, Luis Henrique M. da Silva
Summary: Understanding nonionic surfactant-protein interactions is crucial for both technological and scientific purposes, yet there is a lack of kinetic data. By using surface plasmon resonance (SPR), this study investigated the kinetic and thermodynamic parameters of bovine lactoferrin-Brij58 interactions at different temperatures under physiological conditions. The results showed that the adsorption process was accelerated with increasing temperature, leading to a more thermodynamically stable complex formation. The energetic parameters indicated that the potential energy barrier for complex formation primarily arises from the reduction in system entropy.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Biophysics
Timotej Zuntar, Matjaz Licen, Drago Kuzman, Natan Osterman
Summary: This study investigated the reconstitution process of protein films formed by two monoclonal antibodies. The results showed that the reconstitution pace of the films depends on the concentration of the antibodies, which can be predicted quantitatively by a numerical model. Polysorbate 80 was found to inhibit the reconstitution process of the films.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Chemistry, Applied
Katariina Solin, Maija Vuoriluoto, Alexey Khakalo, Tekla Tammelin
Summary: Highly sensitive and specific diagnostics for cannabis usage are crucial for rapid on-site screening. This study demonstrates the utilization of EDC/NHS coupling chemistry with nanocellulose to obtain efficient anchor layers for the immobilization of anti-immune complex antibodies, thereby improving the sensitivity of THC immunoassays.
CARBOHYDRATE POLYMERS
(2023)
Article
Biochemistry & Molecular Biology
Tingting Wang, Jie Chen, Xiaobo Du, Gang Feng, Tangzhi Dai, Xinxi Li, Dong Liu
Summary: This review outlines the current state of utilizing neutron scattering to investigate monoclonal antibodies (mAbs). The basic knowledge and principles of neutron scattering and mAbs are introduced, followed by specific examples of applications in structure and dynamics research. The review demonstrates and discusses how neutron scattering can be utilized to study the structures and dynamics of mAbs.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
(2022)
Article
Chemistry, Analytical
Devendra Bhandari, Fur-Chi Chen, Roger C. Bridgman
Summary: This study developed a method utilizing magnetic nanoparticles and surface plasmon resonance for rapid detection of Salmonella. The results showed that the sequential two-step sandwich assay and preincubation one-step sandwich assay had higher detection signals compared to the direct assay, with detection limits reaching a high level.
Article
Green & Sustainable Science & Technology
S. Mehdi Niknam, Mansoore Kashaninejad, Isabel Escudero, M. Teresa Sanz, Sagrario Beltran, Jose M. Benito
Summary: Olive pomace, a byproduct of olive oil production rich in phenolic compounds, was extracted and purified using ultrasound-assisted extraction and XAD16 polymeric resin adsorption-desorption method, achieving successful extraction and selective purification of biophenols.
JOURNAL OF CLEANER PRODUCTION
(2021)
Article
Chemistry, Analytical
Benjamin Charron, Alexandre Delorme, Caroline Dubois, Maryam Hojjat Jodaylami, Jean-Francois Masson
Summary: This study reveals the significant impact of human serum albumin (HSA) on the response and binding constants of sensing assays, while bovine serum albumin (BSA) does not show the same effect. The results also highlight the importance of the matrix protein/analyte/receptor interactions in determining the assay response.
Article
Biophysics
Cristina Potrich, Anna Pedrotti, Cecilia Pederzolli, Lorenzo Lunelli
Summary: This study developed different functional surfaces for capturing exosomes and verified their effectiveness through experiments. Among them, the negatively-charged surface performed the best, capturing a large number of exosomes and successfully analyzing their biomarkers.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Brojendra Nath Saren, Srushti Mahajan, Mayur Aalhate, Rahul Kumar, Essha Chatterjee, Indrani Maji, Ujala Gupta, Santosh Kumar Guru, Pankaj Kumar Singh
Summary: This study developed P-selectin-targeted dasatinib nanoparticles coated with chitosan and fucoidan (DST-CH-FUC-NPs), which showed sustained release, reduced hemolytic potential, increased cytotoxicity and cellular uptake compared to free dasatinib. These nanoparticles also demonstrated enhanced ROS production, mitochondrial membrane potential damage, apoptosis induction, cell migration inhibition, and disruption of lysosomal membrane integrity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Weiping Deng, Xiaohui Li, Ya Li, Zhongbing Huang, Yulin Wang, Ning Mu, Juan Wang, Tunan Chen, Ximing Pu, Guangfu Yin, Hua Feng
Summary: This study demonstrates the importance of chirality in nerve repair by constructing a GO-phenylalanine derivative hydrogel system. In vivo experiments show that the dextro group significantly improves functional recovery and histological restoration in rat sciatic nerve repair models. The doped GO promotes angiogenesis and myelination. These results suggest that chirality plays a crucial role in promoting nerve regeneration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xiaoyan Wang, Jin Gao, Yu Gao, Linlin Zhang, Congchao Xu, Qintong Li, Lin Li, Jianliang Xue
Summary: In this study, a highly effective surfactant producer strain, Bacillus Cereus GX7, was isolated from the oil tank bottom sludge of Shengli Oil Field in China. The biosurfactant produced by GX7 was identified as surfactin, a lipopeptide surfactant, through TLC, FT-IR, and LC-MS/MS analysis. The fermentation process of GX7 was optimized using single-factor experiments, focusing on the composition of fermentation medium and fermentation conditions. Glucose and peptone were found to be the best carbon and nitrogen sources, and the optimum temperature, inoculum amount, pH, rotation speed, and fermentation time for the strain were determined to be 30°C, 1%, 7.5, 150 rpm, and 48 h, respectively. After optimization, the surface tension and emulsification index of the fermentation broth were 26.84 mN/m and 57.84%, respectively. Furthermore, the biosurfactant produced by GX7 demonstrated good stability over a wide range of temperature, pH, and salt concentration.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Rodney Marcelo do Nascimento, Christine Grauby-Heywang, Houssem Kahli, Nesrine Debez, Laure Beven, Ivan Helmuth Bechtold, Touria Cohen Bouhacina
Summary: This article presents a theoretical model based on thermodynamic rules to assess the early stages of bacterial biofilm formation on different material surfaces. By utilizing morphological characteristics of bacteria and Atomic Force Microscopy images, the model generates a dataset of energetically minimized states, which can be correlated with bacterial adhesion states.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Filipa A. L. S. Silva, Licinia Timochenco, Raquel Costa-Almeida, Jose Ramiro Fernandes, Susana G. Santos, Fernao D. Magalhaes, Artur M. Pinto
Summary: The study demonstrates that by photoreducing nanosized graphene oxide using ultraviolet radiation, nanometric particles with high light-to-heat conversion efficiency and water stability can be obtained. These nanomaterials exhibit high absorption in the near-infrared region and show no cytotoxicity towards human cells, indicating their potential for safe therapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
D. Costa, V. De Matteis, F. Treso, G. Montani, M. Martino, R. Rinaldi, M. Corrado, M. Cascione
Summary: This review primarily discusses the relationship between contact lens discomfort (CLD) and the surface properties of contact lenses (CLs), specifically the coefficient of friction (CoF). The review emphasizes the importance of introducing a standardized protocol for measuring CoF and calls for a more precise evaluation of the relationship between surface properties and comfort in CLs users.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Debdip Brahma, Tamal Sarkar, Rupal Kaushik, Akshay Narayan Sarangi, Amar Nath Gupta
Summary: This in-vitro study evaluates the effect of reactive oxygen species (ROS) on the structural rearrangement of elastin. The results show that oxidative stress leads to a decrease in protein size and changes in secondary structure, potentially promoting protein aggregation. This study is important for therapeutics aiming to prevent elastin degradation and aging.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Xin Yang, Qiang Wang, Chaoxi Yan, Degang Huang, Yinchang Zhang, Huazheng He, Shouliang Xiong, Congming Li, Pingbo Chen, Tingjun Ye, Dan Hu, Lei Wang
Summary: This study presents a practical and effective strategy to improve osseointegration in patients with osteoporosis. By coating titanium implants with polydopamine followed by strontium modification, the bi-functional implants promote bone regeneration and immune regulation. The results show good biocompatibility, sustained release of strontium ions, and stable osseointegration between bone tissues and implants.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Sengwang Fu, Jianping Zhu, Zhijun Jiang, Yue Cao, Yufei Chen, Lihao Zhang, Sunlong Li, Weipeng Lu, Chengbin Miao, Qing He, Qi Li, Weixing Zhang, Lehao Ren, Yachun Li, Hongchao Shi, Cihui Liu
Summary: Effective management of biofluids is crucial for in vivo surgical interventions. Recent advances include self-sealing needles, drug-eluting stents, and shear-thinning hydrogels. However, complications associated with intestinal mucosal injury and secondary damage still persist. In this study, researchers developed an interpenetrating Janus wettability stent coating that enables unidirectional draining of excessive biofluid. They also demonstrated directional biofluid movement using a self-pumping dressing with potential applications in biofluid collection and disease diagnosis through metal ion detection. This integrated system presents an opportunity for designing wound dressings with effective biofluid management and metal ion detection capabilities.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Maryam Hassani, Mojtaba Kamankesh, Mazda Rad-Malekshahi, Kobra Rostamizadeh, Farhad Rezaee, Ismaeil Haririan, Seyed Mojtaba Daghighi
Summary: Bacterial adhesion and biofilm formation on the surface of biomaterial implants is a critical problem, and a polymer brush coating with antiadhesive and antimicrobial properties has proven to be highly effective in resolving this issue.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Huaihong Zhang, Na Liu, Yuting Zhang, Hui Cang, Zhaosheng Cai, Ziqun Huang, Jun Li
Summary: A functionalized cationic polymer, CR-PQAC, was designed and synthesized for photothermal enhanced antimicrobial therapy. The CR-PQAC nanoparticles exhibited significant antibacterial activity and low cytotoxicity against mammalian cells.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Ipsita Sahu, Priyadarshi Chakraborty
Summary: Peptide nanotechnology bridges the gap between materials and biological worlds by utilizing self-assembly of short-peptide building blocks. Hydrogels engineered from these short peptides show great potential in biomedical applications, but their weak mechanical properties and limited functional diversity need to be addressed. Nanoengineering the networks of these hydrogels by incorporating small molecules, polymers, and inorganic/carbon nanomaterials can enhance their mechanical properties and expand their functional diversity.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Hao Wei, Yajun Gu, Ao Li, Panpan Song, Dingding Liu, Feihu Sun, Xiaofeng Ma, Xiaoyun Qian
Summary: In this study, a stable three-dimensional conductive hydrogel was prepared by cross-linking MXenes to Matrigel hydrogel. The conductive hydrogel promotes the proliferation and differentiation of NSCs, providing new strategies for neural tissue engineering.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)
Article
Biophysics
Yue Zhong, Xiaoli Ge, Juan Zhang, Qun Wei, Feng Wang, Yongke Zhong
Summary: The effect of oxygenic groups on the hemocompatibility of activated carbon was studied through liquid-phase oxidation and subsequent heat treatment. Results showed that the presence of oxygenic groups improved hemocompatibility, while their removal decreased it.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2024)