Natalizumab: a new therapy for acute ischemic stroke?

Neuroinflammatory biomarkers: From stroke diagnosis and prognosis to therapy

(2016) Alba Simats et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Combination of the Immune Modulator Fingolimod With Alteplase in Acute Ischemic StrokeCLINICAL PERSPECTIVE

(2015) Zilong Zhu et al.   CIRCULATION

Advanced neuroprotection for brain ischemia: an alternative approach to minimize stroke damage

(2015) Maria Irene Ayuso et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

A cross-laboratory preclinical study on the effectiveness of interleukin-1 receptor antagonist in stroke

(2015) Samaneh Maysami et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Hematopoietic mobilization: Potential biomarker of response to natalizumab in multiple sclerosis

(2015) M. Mattoscio et al.   NEUROLOGY

Results of a preclinical randomized controlled multicenter trial (pRCT): Anti-CD49d treatment for acute brain ischemia

(2015) Gemma Llovera et al.   Science Translational Medicine

Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke

(2014) Jens Neumann et al.   ACTA NEUROPATHOLOGICA

Neutrophil recruitment to the brain in mouse and human ischemic stroke

(2014) Isabel Perez-de-Puig et al.   ACTA NEUROPATHOLOGICA

Impact of an immune modulator fingolimod on acute ischemic stroke

(2014) Ying Fu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blocking of α4 Integrin Does Not Protect From Acute Ischemic Stroke in Mice

(2014) Friederike Langhauser et al.   STROKE

Heart Disease and Stroke Statistics—2014 Update

(2013) Alan S. Go et al.   CIRCULATION

The science of cerebral ischemia and the quest for neuroprotection: navigating past failure to future success

(2013) Ryan C. Turner et al.   JOURNAL OF NEUROSURGERY

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

(2012) Gaby Enzmann et al.   ACTA NEUROPATHOLOGICA

Systematic Review and Meta-Analysis of the Efficacy of Sphingosine-1-Phosphate (S1P) Receptor Agonist FTY720 (Fingolimod) in Animal Models of Stroke

(2012) Junfeng Liu et al.   INTERNATIONAL JOURNAL OF NEUROSCIENCE

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

(2011) Arthur Liesz et al.   BRAIN

Clinical outcomes of natalizumab-associated progressive multifocal leukoencephalopathy

(2011) P. Vermersch et al.   NEUROLOGY

Acute anti-inflammatory approaches to ischemic stroke

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

Vascular Cell Adhesion Molecule-1 Expression and Signaling During Disease: Regulation by Reactive Oxygen Species and Antioxidants

(2010) Joan M. Cook-Mills et al.   ANTIOXIDANTS & REDOX SIGNALING

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

(2010) C. Kleinschnitz et al.   BLOOD

Natalizumab-associated progressive multifocal leukoencephalopathy in patients with multiple sclerosis: lessons from 28 cases

(2010) David B Clifford et al.   LANCET NEUROLOGY

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions

(2009) Ingo Bartholomäus et al.   NATURE

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Thrombolysis with Alteplase 3 to 4.5 Hours after Acute Ischemic Stroke

(2008) Werner Hacke et al.   NEW ENGLAND JOURNAL OF MEDICINE

MMP-9–Positive Neutrophil Infiltration Is Associated to Blood–Brain Barrier Breakdown and Basal Lamina Type IV Collagen Degradation During Hemorrhagic Transformation After Human Ischemic Stroke

(2008) Anna Rosell et al.   STROKE