Treatment of squamous cell carcinoma of the anus, unresolved areas and future perspectives for research: Perspectives of research needs in anal cancer
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Treatment of squamous cell carcinoma of the anus, unresolved areas and future perspectives for research: Perspectives of research needs in anal cancer
Authors
Keywords
Anal Cancer, Radiotherapy, Chemotherapy, Human Papilloma Virus, Immune Checkpoint Inhibition
Journal
Clinical Colorectal Cancer
Volume -, Issue -, Pages -
Publisher
Elsevier BV
Online
2021-09-15
DOI
10.1016/j.clcc.2021.09.006
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The Prognostic Value of the New Combined Hemo-Eosinophil Inflammation Index (HEI Index): A Multicenter Analysis of Anal Cancer Patients Treated with Concurrent Chemo-Radiation
- (2021) Margherita Rimini et al. Cancers
- Treatment outcomes and prognostic factors after chemoradiotherapy for anal cancer
- (2021) Kathinka S. Slørdahl et al. ACTA ONCOLOGICA
- Nonplatinum‐based therapy with Paclitaxel and Capecitabine for advanced squamous cell carcinomas of the anal canal: A population‐based Danish anal cancer group study
- (2021) Christina Glismand Truelsen et al. Cancer Medicine
- The Clinical Value of Measuring Circulating HPV DNA during Chemo-Radiotherapy in Squamous Cell Carcinoma of the Anus
- (2021) Anna C. Lefèvre et al. Cancers
- Anal cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up☆
- (2021) S. Rao et al. ANNALS OF ONCOLOGY
- Predicting outcomes in anal cancer patients using multi-centre data and distributed learning – A proof-of-concept study
- (2021) Ananya Choudhury et al. RADIOTHERAPY AND ONCOLOGY
- Temporal improvements in loco-regional failure and survival in patients with anal cancer treated with chemo-radiotherapy: treatment cohort study (1990–2014)
- (2020) Hema Sekhar et al. BRITISH JOURNAL OF CANCER
- Atezolizumab plus modified docetaxel-cisplatin-5-fluorouracil (mDCF) regimen versus mDCF in patients with metastatic or unresectable locally advanced recurrent anal squamous cell carcinoma: a randomized, non-comparative phase II SCARCE GERCOR trial
- (2020) Stefano Kim et al. BMC CANCER
- UK national cohort of anal cancer treated with intensity-modulated radiotherapy: One-year oncological and patient-reported outcomes
- (2020) A. Gilbert et al. EUROPEAN JOURNAL OF CANCER
- Patterns of recurrence in anal cancer: a detailed analysis
- (2020) Martin P. Nilsson et al. Radiation Oncology
- Feasibility and Outcome of Routine Use of Concurrent Chemoradiation in HIV-positive Patients With Squamous Cell Anal Cancer
- (2020) Andrew J. Leiker et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- Outcome following local excision of T1 anal cancers—a systematic review
- (2020) T. B. Pedersen et al. INTERNATIONAL JOURNAL OF COLORECTAL DISEASE
- International Rare Cancers Initiative Multicenter Randomized Phase II Trial of Cisplatin and Fluorouracil Versus Carboplatin and Paclitaxel in Advanced Anal Cancer: InterAAct
- (2020) Sheela Rao et al. JOURNAL OF CLINICAL ONCOLOGY
- Patterns of inguinal lymph node metastases in anal canal cancer and recommendations for elective clinical target volume (CTV) delineation
- (2020) Allison E. Garda et al. RADIOTHERAPY AND ONCOLOGY
- Role of metastasectomy for liver metastasis in stage IV anal cancer
- (2020) Matthew Goldner et al. AMERICAN JOURNAL OF SURGERY
- LBA42 POD1UM-202: Phase II study of retifanlimab in patients (pts) with squamous carcinoma of the anal canal (SCAC) who progressed following platinum-based chemotherapy
- (2020) S. Rao et al. ANNALS OF ONCOLOGY
- Association of tumour mutational burden with outcomes in patients with advanced solid tumours treated with pembrolizumab: prospective biomarker analysis of the multicohort, open-label, phase 2 KEYNOTE-158 study
- (2020) Aurélien Marabelle et al. LANCET ONCOLOGY
- HPV Vaccination and the Risk of Invasive Cervical Cancer
- (2020) Jiayao Lei et al. NEW ENGLAND JOURNAL OF MEDICINE
- Measurement of circulating free DNA in squamous cell carcinoma of the anus and relation to risk factors and recurrence
- (2020) Anna Cecilie Lefèvre et al. RADIOTHERAPY AND ONCOLOGY
- Multimodality treatment of oligometastatic anal squamous cell carcinoma: A case series and literature review
- (2019) Francesco Sclafani et al. JOURNAL OF SURGICAL ONCOLOGY
- Early stage anal margin cancer: towards evidence-based management
- (2019) Andrew G Renehan et al. Colorectal Disease
- Immune inflammation indicators in anal cancer patients treated with concurrent chemoradiation: training and validation cohort with online calculator (ARC: Anal Cancer Response Classifier)
- (2019) Andrea Casadei-Gardini et al. Cancer Management and Research
- Anal squamous cell carcinoma – State of the art management and future perspectives
- (2018) Daniel Martin et al. CANCER TREATMENT REVIEWS
- Extended-Field Chemoradiation Therapy for Definitive Treatment of Anal Canal Squamous Cell Carcinoma Involving the Para-Aortic Lymph Nodes
- (2018) Emma B. Holliday et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Toxicity, Tolerability, and Compliance of Concurrent Capecitabine or 5-Fluorouracil in Radical Management of Anal Cancer With Single-dose Mitomycin-C and Intensity Modulated Radiation Therapy: Evaluation of a National Cohort
- (2018) Christopher M. Jones et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Anal Cancer Risk Among People With HIV Infection in the United States
- (2018) Vivian Colón-López et al. JOURNAL OF CLINICAL ONCOLOGY
- Anal Carcinoma, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology
- (2018) Al B. Benson et al. Journal of the National Comprehensive Cancer Network
- Docetaxel, cisplatin, and fluorouracil chemotherapy for metastatic or unresectable locally recurrent anal squamous cell carcinoma (Epitopes-HPV02): a multicentre, single-arm, phase 2 study
- (2018) Stefano Kim et al. LANCET ONCOLOGY
- Phase I–III development of the EORTC QLQ-ANL27, a health-related quality of life questionnaire for anal cancer
- (2018) Samantha C. Sodergren et al. RADIOTHERAPY AND ONCOLOGY
- Prospective evaluation of acute toxicity and patient reported outcomes in anal cancer and plan optimization
- (2018) Camilla Kronborg et al. RADIOTHERAPY AND ONCOLOGY
- Determinants for local tumour control probability after radiotherapy of anal cancer
- (2018) Anders Johnsson et al. RADIOTHERAPY AND ONCOLOGY
- Systemic Therapies for Advanced Squamous Cell Anal Cancer
- (2018) Francesco Sclafani et al. Current Oncology Reports
- Comparing simultaneous integrated boost vs sequential boost in anal cancer patients: results of a retrospective observational study
- (2018) Pierfrancesco Franco et al. Radiation Oncology
- Clinical validity of HPV circulating tumor DNA in advanced anal carcinoma: an ancillary study to the Epitopes-HPV02 trial
- (2018) Alice Bernard-Tessier et al. CLINICAL CANCER RESEARCH
- Rising Incidence and Improved Survival of Anal Squamous Cell Carcinoma in Norway, 1987-2016
- (2018) Marianne Grønlie Guren et al. Clinical Colorectal Cancer
- Is There a Role for an 18F-fluorodeoxyglucose-derived Biological Boost in Squamous Cell Anal Cancer?
- (2018) A. Sabbagh et al. CLINICAL ONCOLOGY
- Best time to assess complete clinical response after chemoradiotherapy in squamous cell carcinoma of the anus (ACT II): a post-hoc analysis of randomised controlled phase 3 trial
- (2017) Robert Glynne-Jones et al. LANCET ONCOLOGY
- Nivolumab for previously treated unresectable metastatic anal cancer (NCI9673): a multicentre, single-arm, phase 2 study
- (2017) Van K Morris et al. LANCET ONCOLOGY
- External validation of leukocytosis and neutrophilia as a prognostic marker in anal carcinoma treated with definitive chemoradiation
- (2017) Antoine Schernberg et al. RADIOTHERAPY AND ONCOLOGY
- Leukocytosis and neutrophilia predicts outcome in anal cancer
- (2017) Antoine Schernberg et al. RADIOTHERAPY AND ONCOLOGY
- Diagnosis and Diagnostic Imaging of Anal Canal Cancer
- (2017) Kristen K. Ciombor et al. Surgical Oncology Clinics of North America
- Human papilloma virus load and PD-1/PD-L1, CD8+ and FOXP3 in anal cancer patients treated with chemoradiotherapy: Rationale for immunotherapy
- (2017) Panagiotis Balermpas et al. OncoImmunology
- Tumour-infiltrating lymphocyte scores effectively stratify outcomes over and above p16 post chemo-radiotherapy in anal cancer
- (2016) Duncan C Gilbert et al. BRITISH JOURNAL OF CANCER
- Biomarkers in anal cancer: from biological understanding to stratified treatment
- (2016) Christopher M Jones et al. BRITISH JOURNAL OF CANCER
- Trends of incidence and survival in squamous-cell carcinoma of the anal canal in France
- (2016) Anne-Marie Bouvier et al. EUROPEAN JOURNAL OF CANCER PREVENTION
- The assessment of local response using magnetic resonance imaging at 3- and 6-month post chemoradiotherapy in patients with anal cancer
- (2016) Rohit Kochhar et al. EUROPEAN RADIOLOGY
- The Role of FDG-PET in the Initial Staging and Response Assessment of Anal Cancer: A Systematic Review and Meta-analysis
- (2015) Michael Jones et al. ANNALS OF SURGICAL ONCOLOGY
- HPV-negative squamous cell carcinoma of the anal canal is unresponsive to standard treatment and frequently carries disruptive mutations in TP53
- (2015) D Meulendijks et al. BRITISH JOURNAL OF CANCER
- Phase I study of cetuximab in combination with 5-fluorouracil, mitomycin C and radiotherapy in patients with locally advanced anal cancer
- (2015) Otilia Leon et al. EUROPEAN JOURNAL OF CANCER
- Clinical trial designs for rare diseases: Studies developed and discussed by the International Rare Cancers Initiative
- (2015) Jan Bogaerts et al. EUROPEAN JOURNAL OF CANCER
- Molecular biology of anal squamous cell carcinoma: implications for future research and clinical intervention
- (2015) Maria-Pia Bernardi et al. LANCET ONCOLOGY
- Low response rate after cetuximab combined with conventional chemoradiotherapy in patients with locally advanced anal cancer: Long-term results of the UNICANCER ACCORD 16 phase II trial
- (2015) Antonin Levy et al. RADIOTHERAPY AND ONCOLOGY
- A tumor control probability model for anal squamous cell carcinoma
- (2015) Rebecca Muirhead et al. RADIOTHERAPY AND ONCOLOGY
- Systematic review of the quality of life issues associated with anal cancer and its treatment with radiochemotherapy
- (2015) Samantha C. Sodergren et al. SUPPORTIVE CARE IN CANCER
- The role of systemic chemotherapy and multidisciplinary management in improving the overall survival of patients with metastatic squamous cell carcinoma of the anal canal
- (2015) Cathy Eng et al. Oncotarget
- Chemoradiotherapy with capecitabine for locally advanced anal carcinoma: an alternative treatment option
- (2014) D Meulendijks et al. BRITISH JOURNAL OF CANCER
- The rising incidence of anal cancer in England 1990-2010: a population-based study
- (2014) J. R. Wilkinson et al. Colorectal Disease
- Long-term Effects of Chemoradiotherapy for Anal Cancer in Patients With HIV Infection
- (2014) Ingeborg B. Fraunholz et al. DISEASES OF THE COLON & RECTUM
- Human papillomavirus DNA load and p16INK4aexpression predict for local control in patients with anal squamous cell carcinoma treated with chemoradiotherapy
- (2014) Franz Rödel et al. INTERNATIONAL JOURNAL OF CANCER
- Human Papillomavirus Genotyping and p16 Expression As Prognostic Factors for Patients With American Joint Committee on Cancer Stages I to III Carcinoma of the Anal Canal
- (2014) Eva Serup-Hansen et al. JOURNAL OF CLINICAL ONCOLOGY
- Anal carcinoma – Survival and recurrence in a large cohort of patients treated according to Nordic guidelines
- (2014) Otilia Leon et al. RADIOTHERAPY AND ONCOLOGY
- Anal cancer: ESMO–ESSO–ESTRO clinical practice guidelines for diagnosis, treatment and follow-up
- (2014) Robert Glynne-Jones et al. RADIOTHERAPY AND ONCOLOGY
- Impaired health-related quality of life after chemoradiotherapy for anal cancer: Late effects in a national cohort of 128 survivors
- (2013) Anne Gry Bentzen et al. ACTA ONCOLOGICA
- Squamous cell carcinoma antigen
- (2013) Matt Williams et al. CANCER
- Phase 1 study of cetuximab in combination with 5-fluorouracil, cisplatin, and radiotherapy in patients with locally advanced anal canal carcinoma
- (2013) Luis O. Olivatto et al. CANCER
- Neutrophil:lymphocyte ratio as a simple and novel biomarker for prediction of locoregional recurrence after chemoradiotherapy for squamous cell carcinoma of the anus
- (2013) E. Toh et al. Colorectal Disease
- Mitomycin or cisplatin chemoradiation with or without maintenance chemotherapy for treatment of squamous-cell carcinoma of the anus (ACT II): a randomised, phase 3, open-label, 2×2 factorial trial
- (2013) Roger D James et al. LANCET ONCOLOGY
- p16INK4A, p53, EGFR expression and KRAS mutation status in squamous cell cancers of the anus: Correlation with outcomes following chemo-radiotherapy
- (2013) Duncan C Gilbert et al. RADIOTHERAPY AND ONCOLOGY
- Faecal incontinence after chemoradiotherapy in anal cancer survivors: Long-term results of a national cohort
- (2013) Anne Gry Bentzen et al. RADIOTHERAPY AND ONCOLOGY
- EGFR and K-ras gene mutation status in squamous cell anal carcinoma: a role for concurrent radiation and EGFR inhibitors?
- (2012) A Paliga et al. BRITISH JOURNAL OF CANCER
- Australasian Gastrointestinal Trials Group (AGITG) Contouring Atlas and Planning Guidelines for Intensity-Modulated Radiotherapy in Anal Cancer
- (2012) Michael Ng et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- RTOG 0529: A Phase 2 Evaluation of Dose-Painted Intensity Modulated Radiation Therapy in Combination With 5-Fluorouracil and Mitomycin-C for the Reduction of Acute Morbidity in Carcinoma of the Anal Canal
- (2012) Lisa A. Kachnic et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Induction Chemotherapy and Dose Intensification of the Radiation Boost in Locally Advanced Anal Canal Carcinoma: Final Analysis of the Randomized UNICANCER ACCORD 03 Trial
- (2012) Didier Peiffert et al. JOURNAL OF CLINICAL ONCOLOGY
- Chemoradiation for the treatment of epidermoid anal cancer: 13-year follow-up of the first randomised UKCCCR Anal Cancer Trial (ACT I)
- (2010) J Northover et al. BRITISH JOURNAL OF CANCER
- Prognostic biomarkers in squamous cell carcinoma of the anus: a systematic review
- (2010) T Lampejo et al. BRITISH JOURNAL OF CANCER
- Dose-Painted Intensity-Modulated Radiation Therapy for Anal Cancer: A Multi-Institutional Report of Acute Toxicity and Response to Therapy
- (2010) Lisa A. Kachnic et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- The Missing Voice of Patients in Drug-Safety Reporting
- (2010) Ethan Basch NEW ENGLAND JOURNAL OF MEDICINE
- Long-term quality of life after radiotherapy for the treatment of anal cancer
- (2009) Prajnan Das et al. CANCER
- Immunosuppressive disorders and risk of anal squamous cell carcinoma: A nationwide cohort study in Denmark, 1978-2005
- (2009) Kåre G. Sunesen et al. INTERNATIONAL JOURNAL OF CANCER
- Intensity-Modulated Radiation Therapy for the Treatment of Squamous Cell Anal Cancer With Para-aortic Nodal Involvement
- (2009) Joseph C. Hodges et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- EXTRA—A Multicenter Phase II Study of Chemoradiation Using a 5 Day per Week Oral Regimen of Capecitabine and Intravenous Mitomycin C in Anal Cancer
- (2008) Rob Glynne-Jones et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Elective Clinical Target Volumes for Conformal Therapy in Anorectal Cancer: A Radiation Therapy Oncology Group Consensus Panel Contouring Atlas
- (2008) Robert J. Myerson et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Fluorouracil, Mitomycin, and Radiotherapy vs Fluorouracil, Cisplatin, and Radiotherapy for Carcinoma of the Anal Canal
- (2008) Jaffer A. Ajani JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started