Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD)

Matrix Metalloproteinases as Therapeutic Targets for Idiopathic Pulmonary Fibrosis

(2015) Vanessa J. Craig et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Ten-Year Trends in Direct Costs of COPD

(2015) Amir Khakban et al.   CHEST

Supplementing Defect in Club Cell Secretory Protein Attenuates Airway Inflammation in COPD

(2015) Anne Sophie Gamez et al.   CHEST

Chlorinated pool attendance, airway epithelium defects and the risks of allergic diseases in adolescents: Interrelationships revealed by circulating biomarkers

(2015) Alfred Bernard et al.   ENVIRONMENTAL RESEARCH

Club cells and CC16: another “smoking gun”? (With potential bullets against COPD)

(2015) Lucie Knabe et al.   EUROPEAN RESPIRATORY JOURNAL

Protective role for club cell secretory protein-16 (CC16) in the development of COPD

(2015) Maria E. Laucho-Contreras et al.   EUROPEAN RESPIRATORY JOURNAL

Depletion of Bone Marrow CCSP-Expressing Cells Delays Airway Regeneration

(2015) Martha L Bustos et al.   MOLECULAR THERAPY

Lung-Function Trajectories Leading to Chronic Obstructive Pulmonary Disease

(2015) Peter Lange et al.   NEW ENGLAND JOURNAL OF MEDICINE

Relation between circulating CC16 concentrations, lung function, and development of chronic obstructive pulmonary disease across the lifespan: a prospective study

(2015) Stefano Guerra et al.   Lancet Respiratory Medicine

Repression of CC16 by Cigarette Smoke (CS) Exposure

(2015) Lingxiang Zhu et al.   PLoS One

Diagnostic Values For Club Cell Secretory Protein (CC16) in Serum of Patients of Combined Pulmonary Fibrosis and Emphysema

(2014) Nariaki Kokuho et al.   COPD-Journal of Chronic Obstructive Pulmonary Disease

Club cell 10-kDa protein attenuates airway mucus hypersecretion and inflammation

(2014) E. Tokita et al.   EUROPEAN RESPIRATORY JOURNAL

Uteroglobin, a Possible Ligand of the Lipoxin Receptor Inhibits Serum Amyloid A-Driven Inflammation

(2014) Giovanni Antico et al.   MEDIATORS OF INFLAMMATION

Secretoglobin 1A1 and 1A1A Differentially Regulate Neutrophil Reactive Oxygen Species Production, Phagocytosis and Extracellular Trap Formation

(2014) Olivier Côté et al.   PLoS One

Association of serum Clara cell protein CC16 with respiratory infections and immune response to respiratory pathogens in elite athletes

(2014) Marcin Kurowski et al.   RESPIRATORY RESEARCH

Club cell secretory protein improves survival in a murine obliterative bronchiolitis model

(2013) Christine Wendt et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Club Cell Protein 16 and Disease Progression in Chronic Obstructive Pulmonary Disease

(2013) Hye Yun Park et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Clara Cell Protein Expression in Human Neonates During Respiratory Distress Syndrome

(2013) Joel Arias-Martínez et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression

(2013) Lauren J. Buro-Auriemma et al.   HUMAN MOLECULAR GENETICS

Antiflammin-1 attenuates bleomycin-induced pulmonary fibrosis in mice

(2013) Wei Liu et al.   RESPIRATORY RESEARCH

Effect of preterm birth on later FEV1: a systematic review and meta-analysis

(2013) Sarah J Kotecha et al.   THORAX

Neonatal Hyperoxic Exposure Persistently Alters Lung Secretoglobins and Annexin A1

(2013) Thomas M. Raffay et al.   Biomed Research International

Serum concentrations of club cell secretory protein (Clara) and cancer mortality in adults: a population-based, prospective cohort study

(2013) Stefano Guerra et al.   Lancet Respiratory Medicine

The club cell and its protein, CC16: time to shine

(2013) Bartolome R Celli et al.   Lancet Respiratory Medicine

Genome-Wide Association Analysis of Blood Biomarkers in Chronic Obstructive Pulmonary Disease

(2012) Deog Kyeom Kim et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease

(2012) Jørgen Vestbo et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Foxm1 transcription factor is critical for proliferation and differentiation of Clara cells during development of conducting airways

(2012) Vladimir Ustiyan et al.   DEVELOPMENTAL BIOLOGY

Alleviation of Lung Inflammatory Responses by Adeno-Associated Virus 2/9 Vector Carrying CC10 in OVA-Sensitized Mice

(2012) Chia-Jen Wu et al.   HUMAN GENE THERAPY

Clara cell 10-kDa protein inhibits TH17 responses through modulating dendritic cells in the setting of allergic rhinitis

(2012) Yang Liu et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Clara Cell 10-kDa Protein Gene Transfection Inhibits NF-κB Activity in Airway Epithelial Cells

(2012) Xiao-Bo Long et al.   PLoS One

Serum amyloid A opposes lipoxin A4 to mediate glucocorticoid refractory lung inflammation in chronic obstructive pulmonary disease

(2012) S. Bozinovski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Airway Epithelial Progenitors Are Region Specific and Show Differential Responses to Bleomycin-Induced Lung Injury

(2012) Huaiyong Chen et al.   STEM CELLS

Claudin-3 and Clara Cell 10 kDa Protein as Early Signals of Cigarette Smoke–Induced Epithelial Injury along Alveolar Ducts

(2012) Snježana Čužić et al.   TOXICOLOGIC PATHOLOGY

Late Intervention with a Myeloperoxidase Inhibitor Stops Progression of Experimental Chronic Obstructive Pulmonary Disease

(2011) Andrew Churg et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Polydatin up-regulates clara cell secretory protein to suppress phospholipase A2 of lung induced by LPS in vivo and in vitro

(2011) Shu Shiyu et al.   BMC CELL BIOLOGY

A water soluble vitamin B12-Re(i) fluorescent conjugate for cell uptake screens: use in the confirmation of cubilin in the lung cancer line A549

(2011) Anthony R. Vortherms et al.   CHEMICAL COMMUNICATIONS

Biomarkers of early respiratory effects in smoking adolescents

(2011) E. Van Miert et al.   EUROPEAN RESPIRATORY JOURNAL

Role of distinct phospholipases A2 and their modulators in meconium aspiration syndrome in human neonates

(2011) Daniele De Luca et al.   INTENSIVE CARE MEDICINE

Adult bronchopulmonary dysplasia: Computed tomography pulmonary findings

(2011) Patrick Wong et al.   Journal of Medical Imaging and Radiation Oncology

Changes in Forced Expiratory Volume in 1 Second over Time in COPD

(2011) Jørgen Vestbo et al.   NEW ENGLAND JOURNAL OF MEDICINE

Respiratory effects associated with wood fuel use: A cross-sectional biomarker study among adolescents

(2011) Erik Van Miert et al.   PEDIATRIC PULMONOLOGY

A Subset of Epithelial Cells with CCSP Promoter Activity Participates in Alveolar Development

(2010) Vedang A. Londhe et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Clara cell secretory protein increases phagocytic and decreases oxidative activity of neutrophils

(2010) P. Katavolos et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Clara Cells Attenuate the Inflammatory Response through Regulation of Macrophage Behavior

(2009) Joshua C. Snyder et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Serum surfactant protein D is steroid sensitive and associated with exacerbations of COPD

(2009) D. A. Lomas et al.   EUROPEAN RESPIRATORY JOURNAL

CC16 Inhibits the Migration of Eosinophils Towards the Formyl Peptide fMLF but not Towards PGD2

(2009) Sofi Johansson et al.   INFLAMMATION

Clara Cell Secretory Protein in Tracheobronchial Aspirates and Umbilical Cord Serum of Extremely Premature Infants with Systemic Inflammation

(2009) Wolfgang Thomas et al.   Neonatology

Higher Levels of the Anti-inflammatory Protein CC10 Are Associated with Improvement in Bronchial Dysplasia and Sputum Cytometric Assessment in Individuals at High Risk for Lung Cancer

(2008) J. Chen et al.   CLINICAL CANCER RESEARCH

Gene Therapy Using Adeno-Associated Virus Vectors

(2008) S. Daya et al.   CLINICAL MICROBIOLOGY REVIEWS

Emphysema in young adult survivors of moderate-to-severe bronchopulmonary dysplasia

(2008) P. M. Wong et al.   EUROPEAN RESPIRATORY JOURNAL

Leukocyte cell surface proteinases: Regulation of expression, functions, and mechanisms of surface localization

(2008) C OWEN   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Opposing regulation of neutrophil apoptosis through the formyl peptide receptor-like 1/lipoxin A4 receptor: implications for resolution of inflammation

(2008) Driss El Kebir et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The protective role of uteroglobin through the modulation of tissue transglutaminase in the experimental crescentic glomerulonephritis

(2008) S. H. Yang et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort

(2008) D A Lomas et al.   THORAX