Aquaporin modulators: a patent review (2010–2015)

Mammalian aquaglyceroporin function in metabolism

(2016) Umberto Laforenza et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Aquaporin-5: from structure to function and dysfunction in cancer

(2016) Inês Direito et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Role of aquaporins in cell proliferation: What else beyond water permeability?

(2016) Ana Galán-Cobo et al.   Channels

Therapeutic options in neuromyelitis optica spectrum disorders

(2016) Joanna Kitley et al.   Expert Review of Neurotherapeutics

Exploring the gating mechanisms of aquaporin-3: new clues for the design of inhibitors?

(2016) A. de Almeida et al.   Molecular BioSystems

Therapeutic options in neuromyelitis optica spectrum disorders

(2016) Joanna Kitley et al.   Expert Review of Neurotherapeutics

The Trafficking of the Water Channel Aquaporin-2 in Renal Principal Cells—a Potential Target for Pharmacological Intervention in Cardiovascular Diseases

(2016) Tanja Vukićević et al.   Frontiers in Pharmacology

Detecting Aquaporin Function and Regulation

(2016) Ana Madeira et al.   Frontiers in Chemistry

Key roles of aquaporins in tumor biology

(2015) Marios C. Papadopoulos et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Aquaporins as diagnostic and therapeutic targets in cancer: How far we are?

(2015) Jian Wang et al.   Journal of Translational Medicine

Expression of Aquaporin-1, Aquaporin-3, and Aquaporin-5 Correlates with Nodal Metastasis in Colon Cancer

(2015) Byung Woog Kang et al.   ONCOLOGY

Challenges and achievements in the therapeutic modulation of aquaporin functionality

(2015) Eric Beitz et al.   PHARMACOLOGY & THERAPEUTICS

Leptin administration restores the altered adipose and hepatic expression of aquaglyceroporins improving the non-alcoholic fatty liver of ob/ob mice

(2015) Amaia Rodríguez et al.   Scientific Reports

Evaluation of Urine Aquaporin-1 and Perilipin-2 Concentrations as Biomarkers to Screen for Renal Cell Carcinoma

(2015) Jeremiah J. Morrissey et al.   JAMA Oncology

Aquaglyceroporins: implications in adipose biology and obesity

(2014) Ana Madeira et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

A Gold Coordination Compound as a Chemical Probe to Unravel Aquaporin-7 Function

(2014) Ana Madeira et al.   CHEMBIOCHEM

The Treatment of Neuromyelitis Optica

(2014) Markus C. Kowarik et al.   JOURNAL OF NEURO-OPHTHALMOLOGY

Therapeutic Potential of Vasopressin-Receptor Antagonists in Heart Failure

(2014) Yasukatsu Izumi et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Role of aquaglyceroporins and caveolins in energy and metabolic homeostasis

(2014) Leire Méndez-Giménez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

(2014) Marios C. Papadopoulos et al.   Nature Reviews Neurology

Human aquaporin-11 is a water and glycerol channel and localizes in the vicinity of lipid droplets in human adipocytes

(2014) Ana Madeira et al.   Obesity

Gold compounds as aquaporin inhibitors: new opportunities for therapy and imaging

(2014) Andreia de Almeida et al.   MedChemComm

Apelin-13 Decreases Lipid Storage in Hypertrophic Adipocytes In Vitro Through the Upregulation of AQP7 Expression by the PI3K Signaling Pathway

(2014) Yongsong Chen   MEDICAL SCIENCE MONITOR

Aquaporin-facilitated transmembrane diffusion of hydrogen peroxide

(2013) Gerd P. Bienert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

The role of mammalian superaquaporins inside the cell

(2013) Kenichi Ishibashi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Parasite aquaporins: Current developments in drug facilitation and resistance

(2013) Jie Song et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Aquaporin Inhibition by Gold(III) Compounds: New Insights

(2013) Ana Paula Martins et al.   ChemMedChem

Reduced hepatic aquaporin-9 and glycerol permeability are related to insulin resistance in non-alcoholic fatty liver disease

(2013) A Rodríguez et al.   INTERNATIONAL JOURNAL OF OBESITY

Neuromyelitis optica IgG does not alter aquaporin-4 water permeability, plasma membrane M1/M23 isoform content, or supramolecular assembly

(2012) Andrea Rossi et al.   GLIA

Aquaporin 4: a player in cerebral edema and neuroinflammation

(2012) Andrew M Fukuda et al.   Journal of Neuroinflammation

Aquaporin 4 and neuromyelitis optica

(2012) Marios C Papadopoulos et al.   LANCET NEUROLOGY

Structure, function and translational relevance of aquaporin dual water and ion channels

(2012) Andrea J. Yool et al.   MOLECULAR ASPECTS OF MEDICINE

Targeting Aquaporin Function: Potent Inhibition of Aquaglyceroporin-3 by a Gold-Based Compound

(2012) Ana Paula Martins et al.   PLoS One

Aquaporins in Clinical Medicine

(2011) A.S. Verkman   Annual Review of Medicine

Aquaglyceroporins serve as metabolic gateways in adiposity and insulin resistance control

(2011) Amaia Rodríguez et al.   CELL CYCLE

Aquaporins at a glance

(2011) A. S. Verkman   JOURNAL OF CELL SCIENCE

Aquaporin-8-facilitated mitochondrial ammonia transport

(2010) Leandro R. Soria et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Critical role of aquaporin-3 in the human epidermal growth factor-induced migration and proliferation in the human gastric adenocarcinoma cells

(2010) Yiming Huang et al.   CANCER BIOLOGY & THERAPY

Urinary Biomarkers for the Early Diagnosis of Kidney Cancer

(2010) Jeremiah J. Morrissey et al.   MAYO CLINIC PROCEEDINGS

Structural context shapes the aquaporin selectivity filter

(2010) D. F. Savage et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Roles of Aquaporin-3 in the Epidermis

(2008) Mariko Hara-Chikuma et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Dysregulation of Renal Aquaporins and Epithelial Sodium Channel in Lithium-Induced Nephrogenic Diabetes Insipidus

(2008) Jakob Nielsen et al.   SEMINARS IN NEPHROLOGY