Asymmetric Catalytic Synthesis of Hexahydropyrrolo‐isoquinolines via Three‐Component 1,3‐Dipolar‐Cycloaddition

Synthesis of Dihydroisoquinoline and Dihydropyridine Derivatives via Asymmetric Dearomative Three-Component Reaction

(2021) Guihua Pan et al.   CCS Chemistry

Asymmetric Construction of Cyclobutanes via Direct Vinylogous Michael Addition/Cyclization of β,γ-Unsaturated Amides

(2020) Yuzhen Chen et al.   ORGANIC LETTERS

Pyrrolo[2,1-a]isoquinoline scaffold in drug discovery: advances in synthesis and medicinal chemistry

(2019) Maria D Matveeva et al.   Future Medicinal Chemistry

Asymmetric Inverse-Electron-Demand Diels–Alder Reaction of β,γ-Unsaturated Amides through Dienolate Catalysis

(2019) Jialiang Qin et al.   ORGANIC LETTERS

Chiral Amino Acids-Derived Catalysts and Ligands

(2018) Xiaohua Liu et al.   CHINESE JOURNAL OF CHEMISTRY

Chiral Nickel(II) Complex Catalyzed Enantioselective Doyle–Kirmse Reaction of α-Diazo Pyrazoleamides

(2018) Xiaobin Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective [3 + 2] cycloaddition and rearrangement of thiazolium salts to synthesize thiazole and 1,4-thiazine derivatives

(2018) Xiying Zhang et al.   Organic Chemistry Frontiers

Asymmetric Synthesis of Tetrahydroindolizines by Bimetallic Relay Catalyzed Cycloaddition of Pyridinium Ylides

(2018) Dong Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Controllable Diastereodivergent Synthesis of Pyrrolo[2,1-a]isoquinolines via Catalytic Intramolecular Acylsulfenylation of Activated Alkenes

(2017) Wei Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Asymmetric [3 + 2] Cycloaddition of 2,2′-Diester Aziridines To Synthesize Pyrrolidine Derivatives

(2017) Yuting Liao et al.   ACS Catalysis

Catalytic Michael/Ring-Closure Reaction of α,β-Unsaturated Pyrazoleamides with Amidomalonates: Asymmetric Synthesis of (−)-Paroxetine

(2016) Yu Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Sequential Photo-oxidative [3 + 2] Cycloaddition/Oxidative Aromatization Reactions for the Synthesis of Pyrrolo[2,1-a]isoquinolines Using Molecular Oxygen as the Terminal Oxidant

(2016) Akitoshi Fujiya et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective direct vinylogous aldol-cyclization cascade reaction between β,γ-unsaturated amides and o-quinones

(2016) Yu Jiang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Visible Light Driven Photocascade Catalysis: Ru(bpy)3(PF6)2/TBHP-Mediated Synthesis of Fused β-Carbolines in Batch and Flow Microreactors

(2016) D. Chandrasekhar et al.   ORGANIC LETTERS

1,3-Dipolar cycloaddition of azinium ylides to alkynyl hetarenes: a synthetic route to indolizine and pyrrolo[2,1-a]isoquinoline based heterobiaryls

(2016) Julia I. Nelina-Nemtseva et al.   TETRAHEDRON

TBAI/TBHP-catalyzed [3 + 2]cycloaddition/oxidation/aromatization cascade and online ESI-MS mechanistic studies: synthesis of pyrrolo[2,1-a]isoquinolines and indolizino[8,7-b]indoles

(2016) Shalini Nekkanti et al.   RSC Advances

Scalable Synthesis of Piperazines Enabled by Visible-Light Irradiation and Aluminum Organometallics

(2015) Samuel Suárez-Pantiga et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances of Catalytic Asymmetric 1,3-Dipolar Cycloadditions

(2015) Takuya Hashimoto et al.   CHEMICAL REVIEWS

Microwave-Assisted Synthesis of Arylated Pyrrolo[2,1-a]Isoquinoline Derivatives via Sequential [3 + 2] Cycloadditions and Suzuki-Miyaura Cross-Couplings in Aqueous Medium

(2015) Kamal M. Dawood et al.   JOURNAL OF HETEROCYCLIC CHEMISTRY

N,N′-Dioxide/Gadolinium(III)-Catalyzed Asymmetric Conjugate Addition of Nitroalkanes to α,β-Unsaturated Pyrazolamides

(2015) Qian Yao et al.   JOURNAL OF ORGANIC CHEMISTRY

1,3-Dipolar cycloadditions of azomethine imines

(2015) Carmen Nájera et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Regioselective Synthesis of Indolizines, Pyrrolo[2,1-a]isoquinolines, and Quinolines

(2015) Seyed Abolghasem Hashemi et al.   SYNTHETIC COMMUNICATIONS

Visible-Light-Induced Formal [3+2] Cycloaddition for Pyrrole Synthesis under Metal-Free Conditions

(2014) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible-light photoredox catalyzed synthesis of pyrroloisoquinolines via organocatalytic oxidation/[3 + 2] cycloaddition/oxidative aromatization reaction cascade with Rose Bengal

(2014) Carlos Vila et al.   Beilstein Journal of Organic Chemistry

Metal-Free Intramolecular Carbocyanation of Alkenes: Catalytic Stereoselective Construction of Pyrrolo[2,1-a]isoquinolines with Multiple Substituents

(2014) Jianming Chen et al.   CHEMISTRY-A EUROPEAN JOURNAL

De Novo Synthesis of Imidazoles by Visible-Light-Induced Photocatalytic Aerobic Oxidation/[3+2] Cycloaddition/Aromatization Cascade

(2014) Qiao-Hui Deng et al.   Chemistry-An Asian Journal

Rings in Drugs

(2014) Richard D. Taylor et al.   JOURNAL OF MEDICINAL CHEMISTRY

Analysis of the Structural Diversity, Substitution Patterns, and Frequency of Nitrogen Heterocycles among U.S. FDA Approved Pharmaceuticals

(2014) Edon Vitaku et al.   JOURNAL OF MEDICINAL CHEMISTRY

Iodine-Catalyzed 1,3-Dipolar Cycloaddition/Oxidation/Aromatization Cascade with Hydrogen Peroxide as the Terminal Oxidant: General Route to Pyrrolo[2,1-a]isoquinolines

(2014) Huan-Ming Huang et al.   JOURNAL OF ORGANIC CHEMISTRY

7,8,9,10-Tetrahydropyrrolo[2,1-a]isoquinolines in the search for new indolizine derivatives

(2014) Mino R. Caira et al.   TETRAHEDRON LETTERS

A general, simple and green process to access pyrrolo[2,1-a]isoquinolines using a KI/TBHP catalytic system

(2014) Huan-Ming Huang et al.   RSC Advances

Photoredox catalytic organic reactions promoted with broadband visible light-absorbing Bodipy-iodo-aza-Bodipy triad photocatalyst

(2014) Song Guo et al.   RSC Advances

C60-Bodipy dyad triplet photosensitizers as organic photocatalysts for photocatalytic tandem oxidation/[3+2] cycloaddition reactions to prepare pyrrolo[2,1-a]isoquinoline

(2013) Ling Huang et al.   CHEMICAL COMMUNICATIONS

Porous material-immobilized iodo-Bodipy as an efficient photocatalyst for photoredox catalytic organic reaction to prepare pyrrolo[2,1-a]isoquinoline

(2013) Song Guo et al.   CHEMICAL COMMUNICATIONS

Synthesis of Pyrrolo[2,1-a]isoquinolines by Multicomponent 1,3-Dipolar Cycloaddition

(2013) Florea Dumitrascu et al.   MOLECULES

Direct synthesis of pyrrolo[2,1-a]isoquinolines by 1,3-dipolar cycloaddition of stabilized isoquinolinium N-ylides with vinyl sulfonium salts

(2013) Jing An et al.   TETRAHEDRON LETTERS

Asymmetric Synthesis of Hexahydropyrrolo-isoquinolines by an Organocatalytic Three-Component Reaction

(2012) Alberto Fraile et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible-Light-Induced Oxidation/[3+2] Cycloaddition/Oxidative Aromatization Sequence: A Photocatalytic Strategy To Construct Pyrrolo[2,1-a]isoquinolines

(2011) You-Quan Zou et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Visible light mediated azomethine ylide formation—photoredox catalyzed [3+2] cycloadditions

(2011) Magnus Rueping et al.   CHEMICAL COMMUNICATIONS

Asymmetric Synthesis of Pyrrolo[2,1-a]isoquinoline Derivatives by 1,3-Dipolar Cycloadditions of Stabilized IsoquinoliniumN-Ylides with Sulfinyl Dipolarophiles

(2011) José Luis García Ruano et al.   JOURNAL OF ORGANIC CHEMISTRY

One-pot two-step tandem reactions for selective synthesis of pyrrolo[2,1-a]isoquinolines and dihydro-, tetrahydro-derivatives

(2011) Ying Han et al.   TETRAHEDRON

Progress on lamellarins

(2011) Daniel Pla et al.   MedChemComm

Structures of New Erythrinan Alkaloids and Nitric Oxide Production Inhibitors from Erythrina crista-galli

(2010) Masaaki Ozawa et al.   CHEMICAL & PHARMACEUTICAL BULLETIN

Cu(ii) catalyzed oxidation-[3+2] cycloaddition-aromatization cascade: Efficient synthesis of pyrrolo [2, 1-a] isoquinolines

(2010) Chenguang Yu et al.   CHEMICAL COMMUNICATIONS

Electrocyclization reactions of vinyl, styryl, and butadienyl conjugated carbonyl/azomethine ylides

(2010) Olcay Anaç et al.   TETRAHEDRON

Facile three-component domino reactions in the regioselective synthesis and antimycobacterial evaluation of novel indolizines and pyrrolo[2,1-a]isoquinolines

(2010) Sivasubramanian Muthusaravanan et al.   TETRAHEDRON LETTERS

Novel hybrids from lamellarin D and combretastatin A 4 as cytotoxic agents

(2009) Li Shen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New approaches for the synthesis of erythrinan alkaloids

(2009) Fengzhi Zhang et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

1,3-Dipolar cycloadditions: applications to the synthesis of antiviral agents

(2009) Carmen Nájera et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cascade condensation, cyclization, intermolecular dipolar cycloaddition by multi-component coupling and application to a synthesis of (±)-crispine A

(2009) Iain Coldham et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Copper-Catalyzed 1,3-Dipolar Cycloadditions

(2008) Levi M. Stanley et al.   CHEMICAL REVIEWS

Anticancer Alkaloid Lamellarins Inhibit Protein Kinases

(2008) Dianne Baunbæk et al.   Marine Drugs