Dendritic cell migration in inflammation and immunity

CXCR4 signaling controls dendritic cell location and activation at steady-state and in inflammation

(2021) Carmen Gallego et al.   BLOOD

Epigenetic Remodeling in Innate Immunity and Inflammation

(2021) Qian Zhang et al.   Annual Review of Immunology

Hypoxia and Innate Immunity: Keeping Up with the HIFsters

(2020) Sean P. Colgan et al.   Annual Review of Immunology

Inhibition of IRF4 in dendritic cells by PRR-independent and -dependent signals inhibit Th2 and promote Th17 responses

(2020) Jihyung Lee et al.   eLife

Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19

(2020) Daniel Blanco-Melo et al.   CELL

Inflammatory Type 2 cDCs Acquire Features of cDC1s and Macrophages to Orchestrate Immunity to Respiratory Virus Infection

(2020) Cedric Bosteels et al.   IMMUNITY

Molecular mechanisms of dendritic cell migration in immunity and cancer

(2020) Charlotte M. de Winde et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Single-cell landscape of bronchoalveolar immune cells in patients with COVID-19

(2020) Mingfeng Liao et al.   NATURE MEDICINE

Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization

(2020) Jeffrey Lian et al.   Cell Reports

Acute SARS-CoV-2 Infection Impairs Dendritic Cell and T Cell Responses

(2020) Runhong Zhou et al.   IMMUNITY

Sirt6 inhibition delays the onset of experimental autoimmune encephalomyelitis by reducing dendritic cell migration

(2020) Giovanni Ferrara et al.   Journal of Neuroinflammation

The Role of HIF in Immunity and Inflammation

(2020) Anne F. McGettrick et al.   Cell Metabolism

Substance P Release by Sensory Neurons Triggers Dendritic Cell Migration and Initiates the Type-2 Immune Response to Allergens

(2020) Caroline Perner et al.   IMMUNITY

Maturation of Monocyte-Derived DCs Leads to Increased Cellular Stiffness, Higher Membrane Fluidity, and Changed Lipid Composition

(2020) Jennifer J. Lühr et al.   Frontiers in Immunology

Intracellular HSP70L1 inhibits human dendritic cell maturation by promoting suppressive H3K27me3 and H2AK119Ub1 histone modifications

(2019) Lin Yi et al.   Cellular & Molecular Immunology

CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis

(2019) Juan Liu et al.   IMMUNITY

Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation

(2019) Huamin Wang et al.   Nature Communications

Colony stimulating factor 1 and its receptor are new potential therapeutic targets for allergic asthma

(2019) Hyung‐Geun Moon et al.   ALLERGY

Chemokines in rheumatic diseases: pathogenic role and therapeutic implications

(2019) Yoshishige Miyabe et al.   Nature Reviews Rheumatology

Chemokine Receptor CCR7 Triggers an Endomembrane Signaling Complex for Spatial Rac Activation

(2019) Julia M. Laufer et al.   Cell Reports

The chemokine receptor CCR7 is a promising target for rheumatoid arthritis therapy

(2018) Georgios L. Moschovakis et al.   Cellular & Molecular Immunology

Dendritic cells in the regulation of immunity and inflammation

(2018) Cheng Qian et al.   SEMINARS IN IMMUNOLOGY

Integrating Physical and Molecular Insights on Immune Cell Migration

(2018) Hélène D. Moreau et al.   TRENDS IN IMMUNOLOGY

Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration

(2018) Hannah Guak et al.   Nature Communications

Airway Epithelial Cell-Derived Colony Stimulating Factor-1 Promotes Allergen Sensitization

(2018) Hyung-Geun Moon et al.   IMMUNITY

The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response

(2018) Caroline L. Sokol et al.   IMMUNITY

Blocking Matrix Metalloproteinase-9 Abrogates Collagen-Induced Arthritis via Inhibiting Dendritic Cell Migration

(2018) Juan He et al.   JOURNAL OF IMMUNOLOGY

Type 1 Conventional CD103+ Dendritic Cells Control Effector CD8+ T Cell Migration, Survival, and Memory Responses During Influenza Infection

(2018) See Liang Ng et al.   Frontiers in Immunology

HSP70L1-mediated intracellular priming of dendritic cell vaccination induces more potent CTL response against cancer

(2016) Shuxun Liu et al.   Cellular & Molecular Immunology

Post-Translational Modification Control of Innate Immunity

(2016) Juan Liu et al.   IMMUNITY

Inflammation-Induced CCR7 Oligomers Form Scaffolds to Integrate Distinct Signaling Pathways for Efficient Cell Migration

(2016) Mark A. Hauser et al.   IMMUNITY

Microbiota induces tonic CCL2 systemic levels that control pDC trafficking in steady state

(2016) M Swiecki et al.   Mucosal Immunology

β-Arrestin drives MAP kinase signalling from clathrin-coated structures after GPCR dissociation

(2016) K. Eichel et al.   NATURE CELL BIOLOGY

The lectin Siglec-G inhibits dendritic cell cross-presentation by impairing MHC class I–peptide complex formation

(2016) Yuanyuan Ding et al.   NATURE IMMUNOLOGY

Altered dendritic cell functions in autoimmune diseases: distinct and overlapping profiles

(2016) Frédéric Coutant et al.   Nature Reviews Rheumatology

Localization of dendritic cells in the gut epithelium requires MAdCAM-1

(2015) Thomas Clahsen et al.   CLINICAL IMMUNOLOGY

Homeostatic NF-κB Signaling in Steady-State Migratory Dendritic Cells Regulates Immune Homeostasis and Tolerance

(2015) Myriam Baratin et al.   IMMUNITY

Regulatory dendritic cells in autoimmunity: A comprehensive review

(2015) Juan Liu et al.   JOURNAL OF AUTOIMMUNITY

Resolvin E1 inhibits dendritic cell migration in the skin and attenuates contact hypersensitivity responses

(2015) Yu Sawada et al.   JOURNAL OF EXPERIMENTAL MEDICINE

MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+Dendritic Cells Independently of TNF-α and the Gut Microbiota

(2015) Karin Hägerbrand et al.   JOURNAL OF IMMUNOLOGY

FTY720 Abrogates Collagen-Induced Arthritis by Hindering Dendritic Cell Migration to Local Lymph Nodes

(2015) Yanping Han et al.   JOURNAL OF IMMUNOLOGY

High-Density Lipoprotein Attenuates Th1 and Th17 Autoimmune Responses by Modulating Dendritic Cell Maturation and Function

(2015) Ioanna Tiniakou et al.   JOURNAL OF IMMUNOLOGY

Innate control of actin nucleation determines two distinct migration behaviours in dendritic cells

(2015) Pablo Vargas et al.   NATURE CELL BIOLOGY

The methyltransferase Ezh2 controls cell adhesion and migration through direct methylation of the extranuclear regulatory protein talin

(2015) Merry Gunawan et al.   NATURE IMMUNOLOGY

Control of adaptive immunity by the innate immune system

(2015) Akiko Iwasaki et al.   NATURE IMMUNOLOGY

Coincidental loss of DOCK8 function in NLRP10-deficient and C3H/HeJ mice results in defective dendritic cell migration

(2015) Jayendra Kumar Krishnaswamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells

(2015) G. Stary et al.   SCIENCE

Polysialylation controls dendritic cell trafficking by regulating chemokine recognition

(2015) E. Kiermaier et al.   SCIENCE

lncRNA Directs Cooperative Epigenetic Regulation Downstream of Chemokine Signals

(2014) Zhen Xing et al.   CELL

Plasmacytoid Dendritic Cells Migrate in Afferent Skin Lymph

(2014) Florentia Pascale et al.   JOURNAL OF IMMUNOLOGY

Arrestin 3 Mediates Endocytosis of CCR7 following Ligation of CCL19 but Not CCL21

(2014) M. A. Byers et al.   JOURNAL OF IMMUNOLOGY

Epigenetic Control ofCcr7Expression in Distinct Lineages of Lung Dendritic Cells

(2014) Timothy P. Moran et al.   JOURNAL OF IMMUNOLOGY

IRF4 in Dendritic Cells Inhibits IL-12 Production and Controls Th1 Immune Responses against Leishmania major

(2014) M. Akbari et al.   JOURNAL OF IMMUNOLOGY

The methyltransferase Setdb2 mediates virus-induced susceptibility to bacterial superinfection

(2014) Christopher Schliehe et al.   NATURE IMMUNOLOGY

Rhbdd3 controls autoimmunity by suppressing the production of IL-6 by dendritic cells via K27-linked ubiquitination of the regulator NEMO

(2014) Juan Liu et al.   NATURE IMMUNOLOGY

TLR-driven early glycolytic reprogramming via the kinases TBK1-IKKɛ supports the anabolic demands of dendritic cell activation

(2014) Bart Everts et al.   NATURE IMMUNOLOGY

Noncoding RNA and its associated proteins as regulatory elements of the immune system

(2014) Martin Turner et al.   NATURE IMMUNOLOGY

The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes

(2014) Maria H Ulvmar et al.   NATURE IMMUNOLOGY

The STAT3-Binding Long Noncoding RNA lnc-DC Controls Human Dendritic Cell Differentiation

(2014) P. Wang et al.   SCIENCE

Influence of Metabolism on Epigenetics and Disease

(2013) William G. Kaelin et al.   CELL

Origins and Functional Specialization of Macrophages and of Conventional and Monocyte-Derived Dendritic Cells in Mouse Skin

(2013) Samira Tamoutounour et al.   IMMUNITY

Conventional and Monocyte-Derived CD11b+ Dendritic Cells Initiate and Maintain T Helper 2 Cell-Mediated Immunity to House Dust Mite Allergen

(2013) Maud Plantinga et al.   IMMUNITY

IRF4 Transcription-Factor-Dependent CD103+CD11b+ Dendritic Cells Drive Mucosal T Helper 17 Cell Differentiation

(2013) Emma K. Persson et al.   IMMUNITY

IRF4 Transcription Factor-Dependent CD11b+ Dendritic Cells in Human and Mouse Control Mucosal IL-17 Cytokine Responses

(2013) Andreas Schlitzer et al.   IMMUNITY

The skin-resident and migratory immune system in steady state and memory: innate lymphocytes, dendritic cells and T cells

(2013) William R Heath et al.   NATURE IMMUNOLOGY

Transcriptional programming of dendritic cells for enhanced MHC class II antigen presentation

(2013) Bryan Vander Lugt et al.   NATURE IMMUNOLOGY

Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen

(2013) Andrew L Doedens et al.   NATURE IMMUNOLOGY

Interstitial Dendritic Cell Guidance by Haptotactic Chemokine Gradients

(2013) M. Weber et al.   SCIENCE

Decisions About Dendritic Cells: Past, Present, and Future

(2012) Ralph M. Steinman   Annual Review of Immunology

DOCK8 is a Cdc42 activator critical for interstitial dendritic cell migration during immune responses

(2012) Y. Harada et al.   BLOOD

Influence of hypoxia-inducible factor 1α on dendritic cell differentiation and migration

(2012) Theresa Köhler et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Ly6Chi Monocytes in the Inflamed Colon Give Rise to Proinflammatory Effector Cells and Migratory Antigen-Presenting Cells

(2012) Ehud Zigmond et al.   IMMUNITY

Cross-presenting CD103+ dendritic cells are protected from influenza virus infection

(2012) Julie Helft et al.   JOURNAL OF CLINICAL INVESTIGATION

Constitutive Plasmacytoid Dendritic Cell Migration to the Splenic White Pulp Is Cooperatively Regulated by CCR7- and CXCR4-Mediated Signaling

(2012) E. Umemoto et al.   JOURNAL OF IMMUNOLOGY

IRF4 Promotes Cutaneous Dendritic Cell Migration to Lymph Nodes during Homeostasis and Inflammation

(2012) S. Bajana et al.   JOURNAL OF IMMUNOLOGY

CCR6/CCR10-mediated plasmacytoid dendritic cell recruitment to inflamed epithelia after instruction in lymphoid tissues

(2011) V. Sisirak et al.   BLOOD

Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1

(2011) Eric V. Dang et al.   CELL

Toll-like Receptor 4 (TLR4) Is Essential for Hsp70-like Protein 1 (HSP70L1) to Activate Dendritic Cells and Induce Th1 Response

(2011) Hongliang Fang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lung CD103+ Dendritic Cells Efficiently Transport Influenza Virus to the Lymph Node and Load Viral Antigen onto MHC Class I for Presentation to CD8 T Cells

(2011) A. W. S. Ho et al.   JOURNAL OF IMMUNOLOGY

Fascin1 Promotes Cell Migration of Mature Dendritic Cells

(2011) Y. Yamakita et al.   JOURNAL OF IMMUNOLOGY

CCR7 Essentially Contributes to the Homing of Plasmacytoid Dendritic Cells to Lymph Nodes under Steady-State As Well As Inflammatory Conditions

(2011) S. Seth et al.   JOURNAL OF IMMUNOLOGY

Afferent lymph–derived T cells and DCs use different chemokine receptor CCR7–dependent routes for entry into the lymph node and intranodal migration

(2011) Asolina Braun et al.   NATURE IMMUNOLOGY

Dendritic cell chemotaxis in 3D under defined chemokine gradients reveals differential response to ligands CCL21 and CCL19

(2011) U. Haessler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation

(2010) C. M. Krawczyk et al.   BLOOD

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas

(2010) Cheolho Cheong et al.   CELL

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

Peripheral CD103+dendritic cells form a unified subset developmentally related to CD8α+conventional dendritic cells

(2010) Brian T. Edelson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Actin-Bundling Protein Palladin Is an Akt1-Specific Substrate that Regulates Breast Cancer Cell Migration

(2010) Y. Rebecca Chin et al.   MOLECULAR CELL

Global phosphorylation analysis of  -arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR)

(2010) K. Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Akt–SREBP nexus: cell signaling meets lipid metabolism

(2010) James R. Krycer et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Cdc42-dependent leading edge coordination is essential for interstitial dendritic cell migration

(2009) T. Lammermann et al.   BLOOD

Fine tuning the immune response with PI3K

(2009) David A. Fruman et al.   IMMUNOLOGICAL REVIEWS

CD207+CD103+dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells

(2009) Sandrine Henri et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Blood-derived inflammatory dendritic cells in lymph nodes stimulate acute T helper type 1 immune responses

(2009) Hideki Nakano et al.   NATURE IMMUNOLOGY

Cross-presentation of viral and self antigens by skin-derived CD103+ dendritic cells

(2009) Sammy Bedoui et al.   NATURE IMMUNOLOGY

Dock8 mutations cripple B cell immunological synapses, germinal centers and long-lived antibody production

(2009) Katrina L Randall et al.   NATURE IMMUNOLOGY

Selective engagement of G protein coupled receptor kinases (GRKs) encodes distinct functions of biased ligands

(2009) D. A. Zidar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a novel AS160 splice variant that regulates GLUT4 translocation and glucose-uptake in rat muscle cells

(2008) Daniela Baus et al.   CELLULAR SIGNALLING

Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression

(2008) A. Ricciardi et al.   MOLECULAR CANCER RESEARCH

Complement C1q chemoattracts human dendritic cells and enhances migration of mature dendritic cells to CCL19 via activation of AKT and MAPK pathways

(2008) Shuxun Liu et al.   MOLECULAR IMMUNOLOGY

Migration of Dendritic Cell Subsets and their Precursors

(2007) Gwendalyn J. Randolph et al.   Annual Review of Immunology

TLR4 signaling in cancer cells promotes chemoattraction of immature dendritic cells via autocrine CCL20

(2007) Li Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS