Gradual downhill running improves age-related skeletal muscle and bone weakness: implication of autophagy and bone morphogenetic proteins

One size may not fit all: anti-aging therapies and sarcopenia

(2016) Tyesha N. Burks et al.   Aging-US

Cardiovascular Responses during Downhill Treadmill Walking at Self-Selected Intensity in Older Adults

(2016) Mandy L. Gault et al.   JOURNAL OF AGING AND PHYSICAL ACTIVITY

Intermittent bout exercise training down-regulates age-associated inflammation in skeletal muscles

(2015) Jeong-Seok Kim et al.   EXPERIMENTAL GERONTOLOGY

Downhill Running Excessive Training Inhibits Hypertrophy in Mice Skeletal Muscles with Different Fiber Type Composition

(2015) Alisson L. da Rocha et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Decreased activity of osteocyte autophagy with aging may contribute to the bone loss in senile population

(2014) Ke Chen et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Resveratrol Partially Prevents Rotenone-Induced Neurotoxicity in Dopaminergic SH-SY5Y Cells through Induction of Heme Oxygenase-1 Dependent Autophagy

(2014) Tsu-Kung Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Structural remodeling of coronary resistance arteries: effects of age and exercise training

(2014) Mina A. Hanna et al.   JOURNAL OF APPLIED PHYSIOLOGY

TGFβ and BMP signaling in skeletal muscle: potential significance for muscle-related disease

(2014) Roberta Sartori et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Mechanical regulation of cancer cell apoptosis and autophagy: Roles of bone morphogenetic protein receptor, Smad1/5, and p38 MAPK

(2013) Sheng-Chieh Lien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mild eccentric exercise increases Hsp72 content in skeletal muscles from adult and late middle-aged rats

(2013) Evan J. H. Lewis et al.   CELL STRESS & CHAPERONES

Chronic resistance training activates autophagy and reduces apoptosis of muscle cells by modulating IGF-1 and its receptors, Akt/mTOR and Akt/FOXO3a signaling in aged rats

(2013) Li Luo et al.   EXPERIMENTAL GERONTOLOGY

Suppression of Autophagy in Osteocytes Mimics Skeletal Aging

(2013) Melda Onal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The bone morphogenetic protein axis is a positive regulator of skeletal muscle mass

(2013) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

BMP signaling controls muscle mass

(2013) Roberta Sartori et al.   NATURE GENETICS

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Aging, Functional Capacity and Eccentric Exercise Training

(2013) Mandy Gault   Aging and Disease

Follistatin-mediated skeletal muscle hypertrophy is regulated by Smad3 and mTOR independently of myostatin

(2012) Catherine E. Winbanks et al.   JOURNAL OF CELL BIOLOGY

Eccentric training improves tendon biomechanical properties: A rat model

(2012) Jean-François Kaux et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Establishment of an animal model for delayed-onset muscle soreness after high-intensity eccentric exercise and its application for investigating the efficacy of low-load eccentric training

(2012) Teppei Munehiro et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Effects of ageing and endurance exercise training on alpha-actinin isoforms in rat plantaris muscle

(2011) Y. Ogura et al.   Acta Physiologica

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Different Molecular and Structural Adaptations with Eccentric and Conventional Strength Training in Elderly Men and Women

(2011) Matthias Mueller et al.   GERONTOLOGY

Heme oxygenase-1-mediated autophagy protects against hepatocyte cell death and hepatic injury from infection/sepsis in mice

(2011) Evie H. Carchman et al.   HEPATOLOGY

Involvement of Oxidative Stress in Age-Related Bone Loss

(2011) Yu-Bin Zhang et al.   JOURNAL OF SURGICAL RESEARCH

Dietary long-chain, but not medium-chain, triglycerides impair exercise performance and uncouple cardiac mitochondria in rats

(2011) Andrew J Murray et al.   Nutrition & Metabolism

Autophagy is a protective mechanism in normal cartilage, and its aging-related loss is linked with cell death and osteoarthritis

(2010) Beatriz Caramés et al.   ARTHRITIS AND RHEUMATISM

Initiating exercise training in late middle age minimally protects muscle contractile function and increases myocyte oxidative damage in senescent rats

(2010) Melissa M. Thomas et al.   EXPERIMENTAL GERONTOLOGY

Estrogen and glucocorticoid regulate osteoblast differentiation through the interaction of bone morphogenetic protein-2 and tumor necrosis factor-α in C2C12 cells

(2010) Yoshinori Matsumoto et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Extracellular BMP-antagonist regulation in development and disease: tied up in knots

(2010) David W. Walsh et al.   TRENDS IN CELL BIOLOGY

Mitochondrial death effectors: Relevance to sarcopenia and disuse muscle atrophy

(2009) Emanuele Marzetti et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Autophagy Is Required to Maintain Muscle Mass

(2009) Eva Masiero et al.   Cell Metabolism

Associations of Physical Activity With Inflammatory Factors, Adipocytokines, and Metabolic Syndrome in Middle-Aged and Older Chinese People

(2009) Zhijie Yu et al.   CIRCULATION

The Adaptor Protein p62/SQSTM1 Targets Invading Bacteria to the Autophagy Pathway

(2009) Y. T. Zheng et al.   JOURNAL OF IMMUNOLOGY

Pro-antioxidant ratio in healthy men exposed to muscle-damaging resistance exercise

(2009) A. Zembron-Lacny et al.   JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY

Increased muscle PGC-1  expression protects from sarcopenia and metabolic disease during aging

(2009) T. Wenz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Skeletal muscle proteolysis in aging

(2008) Lydie Combaret et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

The Atg16L Complex Specifies the Site of LC3 Lipidation for Membrane Biogenesis in Autophagy

(2008) Naonobu Fujita et al.   MOLECULAR BIOLOGY OF THE CELL

How to Live Long and Prosper: Autophagy, Mitochondria, and Aging

(2008) Wei-Lien Yen et al.   PHYSIOLOGY

Autophagy and aging: keeping that old broom working

(2008) Ana Maria Cuervo   TRENDS IN GENETICS

Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and calorie restriction in skeletal muscle

(2007) Emanuele Marzetti et al.   FREE RADICAL BIOLOGY AND MEDICINE