Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
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Title
Brain GLP‐1 and the regulation of food intake: GLP‐1 action in the brain and its implications for GLP‐1 receptor agonists in obesity treatment
Authors
Keywords
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Journal
BRITISH JOURNAL OF PHARMACOLOGY
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2021-07-29
DOI
10.1111/bph.15638
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Note: Only part of the references are listed.- Once-Weekly Semaglutide in Adults with Overweight or Obesity
- (2021) John P.H. Wilding et al. NEW ENGLAND JOURNAL OF MEDICINE
- Glucagon-like peptide-1 (GLP-1) receptor activation dilates cerebral arterioles, increases cerebral blood flow, and mediates remote (pre)conditioning neuroprotection against ischaemic stroke
- (2021) Shereen Nizari et al. BASIC RESEARCH IN CARDIOLOGY
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- (2021) Christian Hölscher BRITISH JOURNAL OF PHARMACOLOGY
- Reappraising the role of the vagus nerve in GLP‐1‐mediated regulation of eating
- (2021) Daniel I. Brierley et al. BRITISH JOURNAL OF PHARMACOLOGY
- Super-resolution microscopy compatible fluorescent probes reveal endogenous glucagon-like peptide-1 receptor distribution and dynamics
- (2020) Julia Ast et al. Nature Communications
- International consensus on the diagnosis and management of dumping syndrome
- (2020) Emidio Scarpellini et al. Nature Reviews Endocrinology
- PPG neurons in the nucleus of the solitary tract modulate heart rate but do not mediate GLP-1 receptor agonist-induced tachycardia in mice
- (2020) Marie K. Holt et al. Molecular Metabolism
- GLP-1 Analogs and DPP-4 Inhibitors in Type 2 Diabetes Therapy: Review of Head-to-Head Clinical Trials
- (2020) Matthew P. Gilbert et al. Frontiers in Endocrinology
- Corrination of a GLP-1 Receptor Agonist for Glycemic Control without Emesis
- (2020) Tito Borner et al. Cell Reports
- Central nervous pathways of insulin action in the control of metabolism and food intake
- (2020) Stephanie Kullmann et al. Lancet Diabetes & Endocrinology
- Intestinal glucagon-like peptide-1 effects on food intake: Physiological relevance and emerging mechanisms
- (2020) Jean-Philippe Krieger PEPTIDES
- Area Postrema Cell Types that Mediate Nausea-Associated Behaviors
- (2020) Chuchu Zhang et al. NEURON
- The Discovery and Development of Liraglutide and Semaglutide
- (2019) Lotte Bjerre Knudsen et al. Frontiers in Endocrinology
- Endogenous GLP-1 in lateral septum promotes satiety and suppresses motivation for food in mice
- (2019) Sarah J. Terrill et al. PHYSIOLOGY & BEHAVIOR
- Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice
- (2019) Youngmi Song et al. Cell Metabolism
- Glucagon-like peptide 1 (GLP-1)
- (2019) T.D. Müller et al. Molecular Metabolism
- THE CONCISE GUIDE TO PHARMACOLOGY 2019/20: G protein‐coupled receptors
- (2019) Stephen P H Alexander et al. BRITISH JOURNAL OF PHARMACOLOGY
- Genetic Identification of Vagal Sensory Neurons That Control Feeding
- (2019) Ling Bai et al. CELL
- Synaptic Inputs to the Mouse Dorsal Vagal Complex and Its Resident Preproglucagon Neurons
- (2019) Marie K. Holt et al. JOURNAL OF NEUROSCIENCE
- A unique olfactory bulb microcircuit driven by neurons expressing the precursor to glucagon-like peptide 1
- (2019) Nicolas Thiebaud et al. Scientific Reports
- Liraglutide Modulates Appetite and Body Weight Through Glucagon-Like Peptide 1 Receptor–Expressing Glutamatergic Neurons
- (2018) Jessica M. Adams et al. DIABETES
- A vitamin B12 conjugate of exendin-4 improves glucose tolerance without associated nausea or hypophagia in rodents
- (2018) Elizabeth G. Mietlicki-Baase et al. DIABETES OBESITY & METABOLISM
- GLP-1 neurons form a local synaptic circuit within the rodent nucleus of the solitary tract
- (2018) J. Patrick Card et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss
- (2018) Jens Juul Holst et al. Surgery for Obesity and Related Diseases
- Loss of dorsomedial hypothalamic GLP-1 signaling reduces BAT thermogenesis and increases adiposity
- (2018) Shin J. Lee et al. Molecular Metabolism
- Efficacy and safety of semaglutide compared with liraglutide and placebo for weight loss in patients with obesity: a randomised, double-blind, placebo and active controlled, dose-ranging, phase 2 trial
- (2018) Patrick M O'Neil et al. LANCET
- Integrated Brain Atlas for Unbiased Mapping of Nervous System Effects Following Liraglutide Treatment
- (2018) Casper Bo Gravesen Salinas et al. Scientific Reports
- Preproglucagon Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food
- (2018) Marie K. Holt et al. DIABETES
- Activation of murine pre-proglucagon–producing neurons reduces food intake and body weight
- (2017) Ronald P. Gaykema et al. JOURNAL OF CLINICAL INVESTIGATION
- Exenatide once weekly versus placebo in Parkinson's disease: a randomised, double-blind, placebo-controlled trial
- (2017) Dilan Athauda et al. LANCET
- Enhanced AMPA Receptor Trafficking Mediates the Anorexigenic Effect of Endogenous Glucagon-like Peptide-1 in the Paraventricular Hypothalamus
- (2017) Ji Liu et al. NEURON
- Ghrelin, CCK, GLP-1, and PYY(3–36): Secretory Controls and Physiological Roles in Eating and Glycemia in Health, Obesity, and After RYGB
- (2017) Robert E. Steinert et al. PHYSIOLOGICAL REVIEWS
- Hindbrain glucagon-like peptide-1 neurons track intake volume and contribute to injection stress-induced hypophagia in meal-entrained rats
- (2016) Alison D. Kreisler et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- GLP-1 and weight loss: unraveling the diverse neural circuitry
- (2016) Scott E. Kanoski et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Sensory Neurons that Detect Stretch and Nutrients in the Digestive System
- (2016) Erika K. Williams et al. CELL
- The incretin hormone glucagon-like peptide 1 increases mitral cell excitability by decreasing conductance of a voltage-dependent potassium channel
- (2016) Nicolas Thiebaud et al. JOURNAL OF PHYSIOLOGY-LONDON
- Hindbrain GLP-1 receptor mediation of cisplatin-induced anorexia and nausea
- (2016) Bart C. De Jonghe et al. PHYSIOLOGY & BEHAVIOR
- Appetite controlled by a cholecystokinin nucleus of the solitary tract to hypothalamus neurocircuit
- (2016) Giuseppe D'Agostino et al. eLife
- PPG neurons of the lower brain stem and their role in brain GLP-1 receptor activation
- (2015) Stefan Trapp et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Transfer of liraglutide from blood to cerebrospinal fluid is minimal in patients with type 2 diabetes
- (2015) M Christensen et al. INTERNATIONAL JOURNAL OF OBESITY
- Intestinal GLP-1 and satiation: from man to rodents and back
- (2015) R E Steinert et al. INTERNATIONAL JOURNAL OF OBESITY
- Development and functions of the choroid plexus–cerebrospinal fluid system
- (2015) Melody P. Lun et al. NATURE REVIEWS NEUROSCIENCE
- Spinally projecting preproglucagon axons preferentially innervate sympathetic preganglionic neurons
- (2015) I.J. Llewellyn-Smith et al. NEUROSCIENCE
- A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management
- (2015) Xavier Pi-Sunyer et al. NEW ENGLAND JOURNAL OF MEDICINE
- Distribution and characterisation of Glucagon-like peptide-1 receptor expressing cells in the mouse brain
- (2015) Simon C. Cork et al. Molecular Metabolism
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- (2014) Susan J. Melhorn et al. APPETITE
- Effect of glucagon-like peptide-1 receptor antagonism on appetite and food intake in healthy men
- (2014) Robert E Steinert et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Incretins and Amylin: Neuroendocrine Communication Between the Gut, Pancreas, and Brain in Control of Food Intake and Blood Glucose
- (2014) Matthew R. Hayes et al. Annual Review of Nutrition
- Glutamatergic phenotype of glucagon-like peptide 1 neurons in the caudal nucleus of the solitary tract in rats
- (2014) H. Zheng et al. Brain Structure & Function
- GLP-1 Secretion Is Increased by Inflammatory Stimuli in an IL-6-Dependent Manner, Leading to Hyperinsulinemia and Blood Glucose Lowering
- (2014) F. Kahles et al. DIABETES
- Circulating Glucagon-like Peptide-1 (GLP-1) Inhibits Eating in Male Rats by Acting in the Hindbrain and Without Inducing Avoidance
- (2014) Mukesh Punjabi et al. ENDOCRINOLOGY
- The arcuate nucleus mediates GLP-1 receptor agonist liraglutide-dependent weight loss
- (2014) Anna Secher et al. JOURNAL OF CLINICAL INVESTIGATION
- Neuronal GLP1R mediates liraglutide’s anorectic but not glucose-lowering effect
- (2014) Stephanie Sisley et al. JOURNAL OF CLINICAL INVESTIGATION
- Hippocampal GLP-1 Receptors Influence Food Intake, Meal Size and Effort-Based Responding for Food through Volume Transmission
- (2014) Ted M Hsu et al. NEUROPSYCHOPHARMACOLOGY
- Differential activation of chemically identified neurons in the caudal nucleus of the solitary tract in non-entrained rats after intake of satiating vs. non-satiating meals
- (2014) Alison D. Kreisler et al. PHYSIOLOGY & BEHAVIOR
- Inactivation of the cardiomyocyte glucagon-like peptide-1 receptor (GLP-1R) unmasks cardiomyocyte-independent GLP-1R-mediated cardioprotection
- (2014) John R. Ussher et al. Molecular Metabolism
- Lipopolysaccharides-Mediated Increase in Glucose-Stimulated Insulin Secretion: Involvement of the GLP-1 Pathway
- (2013) A. T. Nguyen et al. DIABETES
- Identification and Characterization of GLP-1 Receptor-Expressing Cells Using a New Transgenic Mouse Model
- (2013) P. Richards et al. DIABETES
- Incretin hormones and the satiation signal
- (2013) J J Holst INTERNATIONAL JOURNAL OF OBESITY
- Glucagon-like peptide-1 in the rat brain: Distribution of expression and functional implication
- (2012) Guibao Gu et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Preproglucagon (PPG) neurons innervate neurochemicallyidentified autonomic neurons in the mouse brainstem
- (2012) I.J. Llewellyn-Smith et al. NEUROSCIENCE
- GLP-1 Neurons in the Nucleus of the Solitary Tract Project Directly to the Ventral Tegmental Area and Nucleus Accumbens to Control for Food Intake
- (2011) Amber L. Alhadeff et al. ENDOCRINOLOGY
- Glucagon-Like Peptide 1 Receptors in Nucleus Accumbens Affect Food Intake
- (2011) A. M. Dossat et al. JOURNAL OF NEUROSCIENCE
- The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease
- (2011) P. L. McClean et al. JOURNAL OF NEUROSCIENCE
- Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
- (2011) Helga Ellingsgaard et al. NATURE MEDICINE
- Preproglucagon neurons project widely to autonomic control areas in the mouse brain
- (2011) I.J. Llewellyn-Smith et al. NEUROSCIENCE
- Leptin Directly Depolarizes Preproglucagon Neurons in the Nucleus Tractus Solitarius
- (2010) Kazunari Hisadome et al. DIABETES
- Evidence that Intestinal Glucagon-Like Peptide-1 Plays a Physiological Role in Satiety
- (2008) Diana L. Williams et al. ENDOCRINOLOGY
- GLP-1 agonists facilitate hippocampal LTP and reverse the impairment of LTP induced by beta-amyloid
- (2008) Victor A. Gault et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Why is the neurobiology of nausea and vomiting so important?
- (2007) Charles C. Horn APPETITE
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