NEK5 activity regulates the mesenchymal and migratory phenotype in breast cancer cells

NEK5 interacts with LonP1 and its kinase activity is essential for the regulation of mitochondrial functions and mtDNA maintenance

(2021) Camila de Castro Ferezin et al.   FEBS Open Bio

On Broken Ne(c)ks and Broken DNA: The Role of Human NEKs in the DNA Damage Response

(2021) Isadora Carolina Betim Pavan et al.   Cells

Targeting Never-In-Mitosis-A Related Kinase 5 in Cancer: A Review

(2021) Margarite D. Matossian et al.   CURRENT MEDICINAL CHEMISTRY

Expression of the NEK family in normal and cancer tissue: an immunohistochemical study

(2020) Talita Diniz Melo-Hanchuk et al.   BMC CANCER

Checking NEKs: Overcoming a Bottleneck in Human Diseases

(2020) Andressa Peres de Oliveira et al.   MOLECULES

Evaluation of deacetylase inhibition in metaplastic breast carcinoma using multiple derivations of preclinical models of a new patient-derived tumor

(2020) Tiffany C. Chang et al.   PLoS One

NEK5 promotes breast cancer cell proliferation through up-regulation of Cyclin A2

(2019) Jing Pei et al.   MOLECULAR CARCINOGENESIS

NEK5 interacts with topoisomerase IIβ and is involved in the DNA damage response induced by etoposide

(2019) Talita Diniz Melo-Hanchuk et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Breast cancer statistics, 2019

(2019) Carol E. DeSantis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Triple negative breast cancer: Emerging therapeutic modalities and novel combination therapies

(2018) Alice Lee et al.   CANCER TREATMENT REVIEWS

Kinase-targeted cancer therapies: progress, challenges and future directions

(2018) Khushwant S. Bhullar et al.   Molecular Cancer

PKIDB: A Curated, Annotated and Updated Database of Protein Kinase Inhibitors in Clinical Trials

(2018) Fabrice Carles et al.   MOLECULES

Unexplored therapeutic opportunities in the human genome

(2018) Tudor I. Oprea et al.   NATURE REVIEWS DRUG DISCOVERY

Molecular Mechanisms and Emerging Therapeutic Targets of Triple-Negative Breast Cancer Metastasis

(2018) Christiana Neophytou et al.   Frontiers in Oncology

Triple-negative breast cancer: challenges and opportunities of a heterogeneous disease

(2016) Giampaolo Bianchini et al.   Nature Reviews Clinical Oncology

Refinement of Triple-Negative Breast Cancer Molecular Subtypes: Implications for Neoadjuvant Chemotherapy Selection

(2016) Brian D. Lehmann et al.   PLoS One

Pattern of metastasis and outcome in patients with breast cancer

(2015) L. Gerratana et al.   CLINICAL & EXPERIMENTAL METASTASIS

Nek5 promotes centrosome integrity in interphase and loss of centrosome cohesion in mitosis

(2015) Suzanna L. Prosser et al.   JOURNAL OF CELL BIOLOGY

An Optimized microRNA Backbone for Effective Single-Copy RNAi

(2013) Christof Fellmann et al.   Cell Reports

Defining the expressed breast cancer kinome

(2012) Alicia A Midland et al.   CELL RESEARCH

Dissecting the Heterogeneity of Triple-Negative Breast Cancer

(2012) Otto Metzger-Filho et al.   JOURNAL OF CLINICAL ONCOLOGY

On the molecular mechanisms of mitotic kinase activation

(2012) R. Bayliss et al.   Open Biology

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

(2011) Brian D. Lehmann et al.   JOURNAL OF CLINICAL INVESTIGATION

NIMA-related kinases 6, 4, and 5 interact with each other to regulate microtubule organization during epidermal cell expansion in Arabidopsis thaliana

(2011) Hiroyasu Motose et al.   PLANT JOURNAL

Transcriptional control of genes involved in ciliogenesis: a first step in making cilia

(2010) Joëlle Thomas et al.   BIOLOGY OF THE CELL

Cytokine Receptor CXCR4 Mediates Estrogen-Independent Tumorigenesis, Metastasis, and Resistance to Endocrine Therapy in Human Breast Cancer

(2010) Lyndsay V. Rhodes et al.   CANCER RESEARCH

Metastatic Behavior of Breast Cancer Subtypes

(2010) Hagen Kennecke et al.   JOURNAL OF CLINICAL ONCOLOGY