An inhibitory and beneficial effect of chlorpromazine and promethazine (C + P) on hyperglycolysis through HIF-1α regulation in ischemic stroke
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Title
An inhibitory and beneficial effect of chlorpromazine and promethazine (C + P) on hyperglycolysis through HIF-1α regulation in ischemic stroke
Authors
Keywords
Ischemia/reperfusion, Stroke, Phenothiazines, Chlorpromazine and Promethazine (C+P), Pharmacological hypothermia, Hypoxia-induced factor-1α (HIF-1α)
Journal
BRAIN RESEARCH
Volume 1763, Issue -, Pages 147463
Publisher
Elsevier BV
Online
2021-04-01
DOI
10.1016/j.brainres.2021.147463
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Note: Only part of the references are listed.- Neuroprotective Effects of Early Hypothermia Induced by Phenothiazines and DHC in Ischemic Stroke
- (2021) Yun Han et al. Evidence-based Complementary and Alternative Medicine
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- (2020) Song-Feng Chen et al. Molecular Brain
- Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows
- (2020) Daniel González-Nieto et al. Cells
- Artificial Hibernation by Phenothiazines: A Potential Neuroprotective Therapy Against Cerebral Inflammation in Stroke
- (2019) Longfei Guan et al. CURRENT NEUROVASCULAR RESEARCH
- Neuroprotection by mesenchymal stem cell (MSC) administration is enhanced by local cooling infusion (LCI) in ischemia
- (2019) Wenjing Wei et al. BRAIN RESEARCH
- New Endovascular Approach for Hypothermia With Intrajugular Cooling and Neuroprotective Effect in Ischemic Stroke
- (2019) Yunxia Duan et al. STROKE
- Reduced Apoptotic Injury by Phenothiazine in Ischemic Stroke through the NOX-Akt/PKC Pathway
- (2019) Yanna Tong et al. Brain Sciences
- Therapeutic Target and Cell-signal Communication of Chlorpromazine and Promethazine in Attenuating Blood–Brain Barrier Disruption after Ischemic Stroke
- (2018) Fengwu Li et al. CELL TRANSPLANTATION
- Inflammatory cytokines are involved in dihydrocapsaicin (DHC) and regional cooling infusion (RCI)-induced neuroprotection in ischemic rat
- (2018) Di Wu et al. BRAIN RESEARCH
- NADPH Oxidase-Related Pathophysiology in Experimental Models of Stroke
- (2017) Hiroshi Yao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Mitochondrial function in hypoxic ischemic injury and influence of aging
- (2017) P. Benson Ham et al. PROGRESS IN NEUROBIOLOGY
- Hibernation-like neuroprotection in stroke by attenuating brain metabolic dysfunction
- (2017) Brian Forreider et al. PROGRESS IN NEUROBIOLOGY
- Phenothiazines Enhance Mild Hypothermia-induced Neuroprotection via PI3K/Akt Regulation in Experimental Stroke
- (2017) Hong An et al. Scientific Reports
- Neuroprotection by Chlorpromazine and Promethazine in Severe Transient and Permanent Ischemic Stroke
- (2016) Xiaokun Geng et al. MOLECULAR NEUROBIOLOGY
- Adjuvant therapies using normobaric oxygen with hypothermia or ethanol for reducing hyperglycolysis in thromboembolic cerebral ischemia
- (2016) L. Cai et al. NEUROSCIENCE
- Enhanced beneficial effects of mild hypothermia by phenothiazine drugs in stroke therapy
- (2015) Shimeng Liu et al. NEUROLOGICAL RESEARCH
- Reduced apoptosis by combining normobaric oxygenation with ethanol in transient ischemic stroke
- (2013) Xiaokun Geng et al. BRAIN RESEARCH
- Neuroprotection conferred by post-ischemia ethanol therapy in experimental stroke: an inhibitory effect on hyperglycolysis and NADPH oxidase activation
- (2013) Ryan Kochanski et al. JOURNAL OF NEUROCHEMISTRY
- Synergetic Neuroprotection of Normobaric Oxygenation and Ethanol in Ischemic Stroke Through Improved Oxidative Mechanism
- (2013) Xiaokun Geng et al. STROKE
- Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy
- (2012) T. W. H. Meijer et al. CLINICAL CANCER RESEARCH
- The HIF1 target gene NOX2 promotes angiogenesis through urotensin-II
- (2012) Isabel Diebold et al. JOURNAL OF CELL SCIENCE
- Neuroprotective mechanisms of hypothermia in brain ischaemia
- (2012) Midori A. Yenari et al. NATURE REVIEWS NEUROSCIENCE
- NADPH oxidase in stroke and cerebrovascular disease
- (2012) Xian Nan Tang et al. NEUROLOGICAL RESEARCH
- Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia
- (2012) Reiner Kunze et al. STROKE
- Hypoxia and mitochondrial oxidative metabolism
- (2010) Giancarlo Solaini et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Hypoxia-inducible factor 1: Regulator of mitochondrial metabolism and mediator of ischemic preconditioning
- (2010) Gregg L. Semenza BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Hyperglycemia in acute ischemic stroke: pathophysiology and clinical management
- (2010) Nyika D. Kruyt et al. Nature Reviews Neurology
- Comparison of neuroprotective effects in ischemic rats with different hypothermia procedures
- (2010) Fei Wang et al. NEUROLOGICAL RESEARCH
- The Protective Effect of Early Hypothermia on PTEN Phosphorylation Correlates with Free Radical Inhibition in Rat Stroke
- (2009) Sang Mi Lee et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion
- (2009) Hai Chen et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Glucose and NADPH oxidase drive neuronal superoxide formation in stroke
- (2008) Sang Won Suh et al. ANNALS OF NEUROLOGY
- A novel approach to reduce hemorrhagic transformation after interventional management of acute stroke: Catheter-based selective hypothermia
- (2008) Jian Chen et al. MEDICAL HYPOTHESES
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