Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype

Integrated analysis of DNA methylation, immunohistochemistry and mRNA expression, data identifies a methylation expression index (MEI) robustly associated with survival of ER-positive breast cancer patients

(2015) Jonine D. Figueroa et al.   BREAST CANCER RESEARCH AND TREATMENT

Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers

(2015) Michael Christoph Haffner et al.   Oncotarget

Reduced 5-Methylcytosine Level as a Potential Progression Predictor in Patients with T1 or Non-Invasive Urothelial Carcinoma

(2014) Chi-Jung Chung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Characterization of the nuclear localization signal of the mouse TET3 protein

(2013) Peng Xiao et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Ki-67 is a prognostic parameter in breast cancer patients: results of a large population-based cohort of a cancer registry

(2013) E. C. Inwald et al.   BREAST CANCER RESEARCH AND TREATMENT

Decreased 5-Hydroxymethylcytosine (5-hmC) is an Independent Poor Prognostic Factor in Gastric Cancer Patients

(2013) Qi Yang et al.   Journal of Biomedical Nanotechnology

Decrease of 5-Hydroxymethylcytosine Is Associated with Progression of Hepatocellular Carcinoma through Downregulation of TET1

(2013) Chungang Liu et al.   PLoS One

HMGA2/TET1/HOXA9 signaling pathway regulates breast cancer growth and metastasis

(2013) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Perturbations of 5-Hydroxymethylcytosine Patterning in Hematologic Malignancies

(2013) Jozef Madzo et al.   SEMINARS IN HEMATOLOGY

Nuclear Exclusion of TET1 Is Associated with Loss of 5-Hydroxymethylcytosine in IDH1 Wild-Type Gliomas

(2012) Tim Müller et al.   AMERICAN JOURNAL OF PATHOLOGY

Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation

(2012) Yotaro Kudo et al.   CANCER SCIENCE

Loss of 5-Hydroxymethylcytosine Is an Epigenetic Hallmark of Melanoma

(2012) Christine Guo Lian et al.   CELL

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

(2012) Yufei Xu et al.   CELL

Intrinsic and extrinsic negative regulators of nuclear protein transport processes

(2012) Toshihiro Sekimoto et al.   GENES TO CELLS

Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation

(2012) H Yang et al.   ONCOGENE

TET2 Mutations Are Associated with Specific 5-Methylcytosine and 5-Hydroxymethylcytosine Profiles in Patients with Chronic Myelomonocytic Leukemia

(2012) Cristina Pérez et al.   PLoS One

Decreased 5-Hydroxymethylcytosine Is Associated with Neural Progenitor Phenotype in Normal Brain and Shorter Survival in Malignant Glioma

(2012) Brent A. Orr et al.   PLoS One

TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

(2012) Chih-Hung Hsu et al.   Cell Reports

Nuclear export of proteins and drug resistance in cancer

(2011) Joel G. Turner et al.   BIOCHEMICAL PHARMACOLOGY

Genome-Wide DNA Methylation Profiling of CpG Islands in Breast Cancer Identifies Novel Genes Associated with Tumorigenicity

(2011) V. K. Hill et al.   CANCER RESEARCH

Genome-wide Methylation Analysis Identifies Genes Specific to Breast Cancer Hormone Receptor Status and Risk of Recurrence

(2011) M. J. Fackler et al.   CANCER RESEARCH

Hydroxylation of 5-Methylcytosine by TET1 Promotes Active DNA Demethylation in the Adult Brain

(2011) Junjie U. Guo et al.   CELL

Emerging roles of TET proteins and 5-hydroxymethylcytosines in active DNA demethylation and beyond

(2011) Junjie U. Guo et al.   CELL CYCLE

TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation

(2011) Luisa Cimmino et al.   Cell Stem Cell

Advances in DNA methylation: 5-hydroxymethylcytosine revisited

(2011) Christina Dahl et al.   CLINICA CHIMICA ACTA

Protein localization in disease and therapy

(2011) M.-C. Hung et al.   JOURNAL OF CELL SCIENCE

Global DNA hypomethylation is an early event in Helicobacter pylori-related gastric carcinogenesis

(2011) D. Compare et al.   JOURNAL OF CLINICAL PATHOLOGY

Genome-wide Regulation of 5hmC, 5mC, and Gene Expression by Tet1 Hydroxylase in Mouse Embryonic Stem Cells

(2011) Yufei Xu et al.   MOLECULAR CELL

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

(2011) Tian-Peng Gu et al.   NATURE

Genome-wide mapping of 5-hydroxymethylcytosine in embryonic stem cells

(2011) William A. Pastor et al.   NATURE

Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation

(2011) Gabriella Ficz et al.   NATURE

Genomic mapping of 5-hydroxymethylcytosine in the human brain

(2011) Seung-Gi Jin et al.   NUCLEIC ACIDS RESEARCH

Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA

(2011) Y.-F. He et al.   SCIENCE

Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine

(2011) S. Ito et al.   SCIENCE

Evaluation of global DNA hypomethylation in human prostate cancer and prostatic intraepithelial neoplasm tissues by immunohistochemistry

(2011) Bo Yang et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

TET1 is a DNA-binding protein that modulates DNA methylation and gene transcription via hydroxylation of 5-methylcytosine

(2010) Haikuo Zhang et al.   CELL RESEARCH

Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1

(2009) M. Tahiliani et al.   SCIENCE

CRM1-Mediated Nuclear Export of Proteins and Drug Resistance in Cancer

(2008) Joel Turner et al.   CURRENT MEDICINAL CHEMISTRY

Epigenetics in Cancer

(2008) Manel Esteller   NEW ENGLAND JOURNAL OF MEDICINE