Scavenging amyloid oligomers from neurons with silica nanobowls: Implications for amyloid diseases

Amyloid Oligomers: A Joint Experimental/Computational Perspective on Alzheimer’s Disease, Parkinson’s Disease, Type II Diabetes, and Amyotrophic Lateral Sclerosis

(2021) Phuong H. Nguyen et al.   CHEMICAL REVIEWS

Silica Nanodepletors: Targeting and Clearing Alzheimer's β‐Amyloid Plaques

(2020) Huijin Jung et al.   ADVANCED FUNCTIONAL MATERIALS

Cerium Oxide Nanoparticles Rescue α-Synuclein-Induced Toxicity in a Yeast Model of Parkinson’s Disease

(2020) Roberta Ruotolo et al.   Nanomaterials

Aβ(1-42) tetramer and octamer structures reveal edge conductivity pores as a mechanism for membrane damage

(2020) Sonia Ciudad et al.   Nature Communications

Lipid-Encapsulated Silica Nanobowls as an Efficient and Versatile DNA Delivery System

(2020) Madhura Som et al.   BIOCONJUGATE CHEMISTRY

Magnetite/Ceria Nanoparticle Assemblies for Extracorporeal Cleansing of Amyloid‐β in Alzheimer's Disease

(2019) Dokyoon Kim et al.   ADVANCED MATERIALS

Detecting Alpha Synuclein Seeding Activity in Formaldehyde-Fixed MSA Patient Tissue by PMCA

(2018) Katelyn Becker et al.   MOLECULAR NEUROBIOLOGY

A self-destructive nanosweeper that captures and clears amyloid β-peptides

(2018) Qiang Luo et al.   Nature Communications

Magnetic Fluorescent Nanoparticles Binding to Amyloid-Beta Peptide: Silica-Coated, Thioflavin-T Functionalized Iron Oxide

(2017) Apostolos C. Tsolakis et al.   IEEE TRANSACTIONS ON MAGNETICS

Mesoporous silica nanoparticles trigger mitophagy in endothelial cells and perturb neuronal network activity in a size- and time-dependent manner

(2017) Antonina Orlando et al.   International Journal of Nanomedicine

Antibody-conjugated mesoporous silica nanoparticles for brain microvessel endothelial cell targeting

(2017) Meryem Bouchoucha et al.   Journal of Materials Chemistry B

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Membrane-bound tetramer and trimer Aβ oligomeric species correlate with toxicity towards cultured neurons

(2016) Metta K. Jana et al.   JOURNAL OF NEUROCHEMISTRY

Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate

(2016) Ting Yang et al.   JOURNAL OF NEUROSCIENCE

Magnetically-responsive silica–gold nanobowls for targeted delivery and SERS-based sensing

(2016) Alexander H. Mo et al.   Nanoscale

Distinct prion-like strains of amyloid beta implicated in phenotypic diversity of Alzheimer's disease

(2016) Mark Cohen et al.   Prion

Aβ42 assembles into specific β-barrel pore-forming oligomers in membrane-mimicking environments

(2016) Montserrat Serra-Batiste et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-speed atomic force microscopy reveals structural dynamics of amyloid β1–42aggregates

(2016) Takahiro Watanabe-Nakayama et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of thermosensitive poly(N-isopropylacrylamide) on blood coagulation

(2016) Yi Zhang et al.   Journal of Materials Chemistry B

Common molecular mechanism of amyloid pore formation by Alzheimer’s β-amyloid peptide and α-synuclein

(2016) Coralie Di Scala et al.   Scientific Reports

Cell-Membrane-Mimicking Lipid-Coated Nanoparticles Confer Raman Enhancement to Membrane Proteins and Reveal Membrane-Attached Amyloid-β Conformation

(2015) Debanjan Bhowmik et al.   ACS Nano

The Essential Role of Soluble Aβ Oligomers in Alzheimer’s Disease

(2015) Zi-Xuan Wang et al.   MOLECULAR NEUROBIOLOGY

Quaternary Structure Defines a Large Class of Amyloid-β Oligomers Neutralized by Sequestration

(2015) Peng Liu et al.   Cell Reports

Adsorption and separation of amyloid beta aggregates using ferromagnetic nanoparticles coated with charged polymer brushes

(2015) Tong Bu et al.   Journal of Materials Chemistry B

High-resolution NMR characterization of low abundance oligomers of amyloid-β without purification

(2015) Samuel A. Kotler et al.   Scientific Reports

The multifaceted nature of amyloid precursor protein and its proteolytic fragments: friends and foes

(2014) Hoang S. Nhan et al.   ACTA NEUROPATHOLOGICA

Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease

(2014) Samuel A. Kotler et al.   CHEMICAL SOCIETY REVIEWS

The microfluidic multitrap nanophysiometer for hematologic cancer cell characterization reveals temporal sensitivity of the calcein-AM efflux assay

(2014) Thomas F. Byrd IV et al.   Scientific Reports

PEGylated Nanoparticles Bind to and Alter Amyloid-Beta Peptide Conformation: Toward Engineering of Functional Nanomedicines for Alzheimer’s Disease

(2012) Davide Brambilla et al.   ACS Nano

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

SILAC-based proteomic analysis to investigate the impact of amyloid precursor protein expression in neuronal-like B103 cells

(2012) Dale Chaput et al.   ELECTROPHORESIS

Mechanisms for the Insertion of Toxic, Fibril-like β-Amyloid Oligomers into the Membrane

(2012) Hyunbum Jang et al.   Journal of Chemical Theory and Computation

Aβ42 oligomers, but not fibrils, simultaneously bind to and cause damage to ganglioside-containing lipid membranes

(2011) Thomas L. Williams et al.   BIOCHEMICAL JOURNAL

Membrane and surface interactions of Alzheimer’s Aβ peptide - insights into the mechanism of cytotoxicity

(2011) Thomas L. Williams et al.   FEBS Journal

Protein Adsorption on Poly(N-isopropylacrylamide) Brushes: Dependence on Grafting Density and Chain Collapse

(2011) Changying Xue et al.   LANGMUIR

Soluble amyloid  -protein dimers isolated from Alzheimer cortex directly induce Tau hyperphosphorylation and neuritic degeneration

(2011) M. Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polymorphism of amyloid β peptide in different environments: implications for membrane insertion and pore formation

(2011) Fernando Terán Arce et al.   Soft Matter

Dual Effect of Amino Modified Polystyrene Nanoparticles on Amyloid β Protein Fibrillation

(2010) Celia Cabaleiro-Lago et al.   ACS Chemical Neuroscience

Lipid-based nanoparticles with high binding affinity for amyloid-β1–42 peptide

(2010) Marco Gobbi et al.   BIOMATERIALS

Preparation and characterization of toxic Aβ aggregates for structural and functional studies in Alzheimer's disease research

(2010) Asad Jan et al.   Nature Protocols

Driving force of binding of amyloid β-protein to lipid bilayers

(2008) Keisuke Ikeda et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

TiO2 nanoparticles promote β-amyloid fibrillation in vitro

(2008) Wei-hui Wu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Soluble Amyloid β-Oligomers Affect Dielectric Membrane Properties by Bilayer Insertion and Domain Formation: Implications for Cell Toxicity

(2008) Gintaras Valincius et al.   BIOPHYSICAL JOURNAL

Alzheimer's disease-type neuronal tau hyperphosphorylation induced by Aβ oligomers

(2007) Fernanda G. De Felice et al.   NEUROBIOLOGY OF AGING