Molecular design and preparation of 2-aminothiazole sulfanilamide oximes as membrane active antibacterial agents for drug resistant Acinetobacter baumannii

Pyrimidinetrione‐imidazoles as a Unique Structural Type of Potential Agents towards Candida Albicans : Design, Synthesis and Biological Evaluation

(2021) Yan‐Fei Sui et al.   Chemistry-An Asian Journal

Design and Synthesis of Sulfanilamide Aminophosphonates as Novel Antibacterial Agents towards Escherichia Coli

(2021) Juan Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Membrane active 7-thiazoxime quinolones as novel DNA binding agents to decrease the genes expression and exert potent anti-methicillin-resistant Staphylococcus aureus activity

(2021) Jin-Ping Chen et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, Synthesis, and Fungicidal Activities of Novel Piperidyl Thiazole Derivatives Containing Oxime Ether or Oxime Ester Moieties

(2021) Qiang Bian et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Identification of Unique Quinazolone Thiazoles as Novel Structural Scaffolds for Potential Gram-Negative Bacterial Conquerors

(2021) Jie Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Isatin-derived azoles as new potential antimicrobial agents: Design, synthesis and biological evaluation

(2021) Vijai Kumar Reddy Tangadanchu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Unique para-aminobenzenesulfonyl oxadiazoles as novel structural potential membrane active antibacterial agents towards drug-resistant methicillin resistant Staphylococcus aureus

(2021) Juan Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel carbazole-oxadiazoles as potential Staphylococcus aureus germicides

(2021) Yun-Peng Xie et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Design and biological evaluation of a novel type of potential multi-targeting antimicrobial sulfanilamide hybrids in combination of pyrimidine and azoles

(2020) Yan-Fei Sui et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel Diindoloazepinone Derivatives as DNA Minor Groove Binding Agents with Selective Topoisomerase I Inhibition: Design, Synthesis, Biological Evaluation and Docking Studies

(2020) Manasa Kadagathur et al.   BIOORGANIC CHEMISTRY

Cutaneous Adverse Events Caused by Sulfonamide-Containing Drugs: Reality or Perception?

(2020) Falgun Shah et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thiazoles, Their Benzofused Systems, and Thiazolidinone Derivatives: Versatile and Promising Tools to Combat Antibiotic Resistance

(2020) Stella Cascioferro et al.   JOURNAL OF MEDICINAL CHEMISTRY

Small Molecule Carboxylates Inhibit Metallo-β-lactamases and Resensitize Carbapenem-Resistant Bacteria to Meropenem

(2020) Kamaleddin H. M. E. Tehrani et al.   ACS Infectious Diseases

Microbial synthesized cadmium oxide nanoparticles induce oxidative stress and protein leakage in bacterial cells

(2020) Zara Azam et al.   MICROBIAL PATHOGENESIS

Ultrasound-assisted multicomponent synthesis of 4H-pyrans in water and DNA binding studies

(2020) Fernando Auria-Luna et al.   Scientific Reports

Discovery, synthesis and biological evaluation of dunnianol-based Mannich bases against methicillin-resistant Staphylococcus aureus (MRSA)

(2020) Yong Guo et al.   ACS Infectious Diseases

Periplasmic targets for the development of effective antimicrobials against gram-negative bacteria

(2020) Ankit Pandeya et al.   ACS Infectious Diseases

1,2,3-Triazolylmethaneboronate: A Structure Activity Relationship Study of a Class of β-Lactamase Inhibitors against Acinetobacter baumannii Cephalosporinase

(2020) Emilia Caselli et al.   ACS Infectious Diseases

An unexpected discovery toward novel membrane active sulfonyl thiazoles as potential MRSA DNA intercalators

(2020) Yuan-Yuan Hu et al.   Future Medicinal Chemistry

Development of Bis-cyclic Imidazolidine-4-one Derivatives as Potent Antibacterial Agents

(2020) Minghui Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nature-Inspired (di)Azine-Bridged Bisindole Alkaloids with Potent Antibacterial In Vitro and In Vivo Efficacy against Methicillin-Resistant Staphylococcus aureus

(2020) Nidja Rehberg et al.   JOURNAL OF MEDICINAL CHEMISTRY

Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope

(2020) Edward Geisinger et al.   Nature Communications

Outer Membranes of Polymyxin-Resistant Acinetobacter baumannii with Phosphoethanolamine-Modified Lipid A and Lipopolysaccharide Loss Display Different Atomic-Scale Interactions with Polymyxins

(2020) Xukai Jiang et al.   ACS Infectious Diseases

Synthesis and Biological Evaluation of Quinazolonethiazoles as New Potential Conquerors towards Pseudomonas Aeruginosa

(2020) Jie Wang et al.   CHINESE JOURNAL OF CHEMISTRY

Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo

(2020) Xiaomin Guo et al.   ACS Infectious Diseases

Exogenous Nitric Oxide Improves Antibiotic Susceptibility in Resistant Bacteria

(2020) Kaitlyn R. Rouillard et al.   ACS Infectious Diseases

Reactive oxygen and nitrogen species and innate immune response

(2020) Saad S. Al-Shehri   BIOCHIMIE

Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance

(2020) Yinhu Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

New derivatives of 4′-phenyl-2,2’:6′,2″-terpyridine as promising anticancer agents

(2020) Katarzyna Malarz et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Sulfonamide-derived Four-component Molecular Hybrids as Novel DNA-targeting Membrane Active Potentiators against Clinical Escherichia coli

(2019) Yuan-Yuan Hu et al.   MOLECULAR PHARMACEUTICS

Design and synthesis of aminothiazolyl norfloxacin analogues as potential antimicrobial agents and their biological evaluation

(2019) Liang-Liang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Glutathione S-Transferase Regulates Mitochondrial Populations in Axons through Increased Glutathione Oxidation

(2019) Gaynor A. Smith et al.   NEURON

Synthesis and Bioactivities of New Membrane-Active Agents with Aromatic Linker: High Selectivity and Broad-Spectrum Antibacterial Activity

(2019) Wenchao Chu et al.   ACS Infectious Diseases

Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus

(2019) Chun-Fang Hu et al.   BIOORGANIC CHEMISTRY

A new exploration towards aminothiazolquinolone oximes as potentially multi-targeting antibacterial agents: Design, synthesis and evaluation acting on microbes, DNA, HSA and topoisomerase IV

(2019) Liang-Liang Wang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Indole-nitroimidazole conjugates as efficient manipulators to decrease the genes expression of methicillin-resistant Staphylococcus aureus

(2019) Zhen-Zhen Li et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Lysine-Based Small Molecule Sensitizes Rifampicin and Tetracycline against Multidrug-Resistant Acinetobacter baumannii and Pseudomonas aeruginosa

(2019) Mohini Mohan Konai et al.   ACS Infectious Diseases

Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors

(2019) Mohamed A. Said et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel purine benzimidazoles as antimicrobial agents by regulating ROS generation and targeting clinically resistant Staphylococcus aureus DNA groove

(2018) Ya-Nan Wang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Novel aminopyrimidinyl benzimidazoles as potentially antimicrobial agents: Design, synthesis and biological evaluation

(2018) Han-Bo Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

(2018) Wei-Wei Gao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel carbazole-triazole conjugates as DNA-targeting membrane active potentiators against clinical isolated fungi

(2018) Yuan Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel naphthalimide nitroimidazoles as multitargeting antibacterial agents against resistant Acinetobacter baumannii

(2018) Jie Kang et al.   Future Medicinal Chemistry

Potential Antimicrobial Isopropanol-Conjugated Carbazole Azoles as Dual Targeting Inhibitors of Enterococcus faecalis

(2018) Yuan Zhang et al.   ACS Medicinal Chemistry Letters

A new class of synthetic retinoid antibiotics effective against bacterial persisters

(2018) Wooseong Kim et al.   NATURE

The Pseudomonas aeruginosa Complement of Lactate Dehydrogenases Enables Use of D- and L-Lactate and Metabolic Cross-Feeding

(2018) Yu-Cheng Lin et al.   mBio

Bacterial inactivation by plasma treated water enhanced by reactive nitrogen species

(2018) Priyanka Shaw et al.   Scientific Reports

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

(2018) Chuang Zhao et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and antimicrobial evaluation of novel benzimidazole-incorporated sulfonamide analogues

(2017) Hui-Zhen Zhang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Design, synthesis and biological evaluation of amino organophosphorus imidazoles as a new type of potential antimicrobial agents

(2017) Wei-Wei Gao et al.   Science China-Chemistry

Discovery of natural berberine-derived nitroimidazoles as potentially multi-targeting agents against drug-resistant Escherichia coli

(2017) Guo-Biao Zhang et al.   Science China-Chemistry

A Review on Synthetic Applications of Oxime Esters

(2016) Esmail Vessally et al.   CURRENT ORGANIC CHEMISTRY

Synthesis and biological evaluation of pyrrolo[2,3- b ]pyridine analogues as antiproliferative agents and their interaction with calf thymus DNA

(2016) Suresh Narva et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Novel 3-Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

(2016) Sheng-Feng Cui et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Progress in Azole Compounds as Antimicrobial Agents

(2016) Hui-Zhen Zhang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Oxidative stress generation of silver nanoparticles in three bacterial genera and its relationship with the antimicrobial activity

(2016) M.A. Quinteros et al.   TOXICOLOGY IN VITRO

Synthesis and biological evaluation of Schiff base-linked imidazolyl naphthalimides as novel potential anti-MRSA agents

(2016) Huo-Hui Gong et al.   MedChemComm

Synthesis and antimicrobial activity of esters of 3-ethoxy-4-hydroxybenzaldehyde oxime

(2016) Vivek Ahluwalia et al.   TOXICOLOGICAL AND ENVIRONMENTAL CHEMISTRY

Synthesis of novel sulfonamide azoles via C–N cleavage of sulfonamides by azole ring and relational antimicrobial study

(2015) Hui-Zhen Zhang et al.   NEW JOURNAL OF CHEMISTRY

Lactate Dehydrogenase Is the Key Enzyme for Pneumococcal Pyruvate Metabolism and Pneumococcal Survival in Blood

(2014) Paula Gaspar et al.   INFECTION AND IMMUNITY

Recent Developments in Azole Compounds as Antibacterial and Antifungal Agents

(2013) Xin-Mei Peng et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Comprehensive Review in Current Developments of Imidazole-Based Medicinal Chemistry

(2013) Ling Zhang et al.   MEDICINAL RESEARCH REVIEWS

Recent Researches in Triazole Compounds as Medicinal Drugs

(2012) C. -H. Zhou et al.   CURRENT MEDICINAL CHEMISTRY

Synthesis and evaluation of a class of new coumarin triazole derivatives as potential antimicrobial agents

(2010) Yuan Shi et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS