Mdivi-1, a mitochondrial fission inhibitor, reduces angiotensin-II- induced hypertension by mediating VSMC phenotypic switch

DNA-PKcs promotes cardiac ischemia reperfusion injury through mitigating BI-1-governed mitochondrial homeostasis

(2020) Hao Zhou et al.   BASIC RESEARCH IN CARDIOLOGY

Involvement of Senescence and Mitochondrial Fission in Endothelial Cell Pro-Inflammatory Phenotype Induced by Angiotensin II

(2020) Masashi Miyao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diallyl Trisulfide Suppresses Angiotensin II–Induced Vascular Remodeling Via Inhibition of Mitochondrial Fission

(2020) Zhao-Yang Lu et al.   CARDIOVASCULAR DRUGS AND THERAPY

78 kDa Glucose-Regulated Protein Attenuates Protein Aggregation and Monocyte Adhesion Induced by Angiotensin II in Vascular Cells

(2020) Stephanie Cicalese et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitophagy inhibitor liensinine suppresses doxorubicin-induced cardiotoxicity through inhibition of Drp1-mediated maladaptive mitochondrial fission

(2020) Xinyue Liang et al.   PHARMACOLOGICAL RESEARCH

Deficiency in Aim2 affects viability and calcification of vascular smooth muscle cells from murine aortas and angiotensin-II induced aortic aneurysms

(2020) Markus Wortmann et al.   MOLECULAR MEDICINE

Interleukin-11 is important for vascular smooth muscle phenotypic switching and aortic inflammation, fibrosis and remodeling in mouse models

(2020) Wei-Wen Lim et al.   Scientific Reports

Mdivi-1 attenuates oxidative stress and exerts vascular protection in ischemic/hypoxic injury by a mechanism independent of Drp1 GTPase activity

(2020) Chenyang Duan et al.   Redox Biology

Tobacco Smoking Induces Cardiovascular Mitochondrial Oxidative Stress, Promotes Endothelial Dysfunction and Enhances Hypertension

(2019) Sergey Dikalov et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction

(2019) Qiang Li et al.   Redox Biology

Carbonic Anhydrase Inhibition Ameliorates Inflammation and Experimental Pulmonary Hypertension

(2019) Hannes Hudalla et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Mitophagy and mitochondrial integrity in cardiac ischemia-reperfusion injury

(2019) Mingjie Yang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mdivi-1, a mitochondrial fission inhibitor, modulates T helper cells and suppresses the development of experimental autoimmune encephalomyelitis

(2019) Yan-Hua Li et al.   Journal of Neuroinflammation

Targeting Mitochondrial Fission Using Mdivi-1 in A Clinically Relevant Large Animal Model of Acute Myocardial Infarction: A Pilot Study

(2019) Sang-Bing Ong et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Dynamics of Dynamin-Related Protein 1 in Alzheimer’s Disease and Other Neurodegenerative Diseases

(2019) Darryll Oliver et al.   Cells

Mdivi-1 alleviates blood-brain barrier disruption and cell death in experimental traumatic brain injury by mitigating autophagy dysfunction and mitophagy activation

(2018) Qiong Wu et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondrial Fission Is Required for Angiotensin II-Induced Cardiomyocyte Apoptosis Mediated by a Sirt1-p53 Signaling Pathway

(2018) Jia Qi et al.   Frontiers in Pharmacology

Mitochondrial division inhibitor 1 reduces dynamin-related protein 1 and mitochondrial fission activity

(2018) Maria Manczak et al.   HUMAN MOLECULAR GENETICS

Mdivi-1 Protects Adult Rat Hippocampal Neural Stem Cells against Palmitate-Induced Oxidative Stress and Apoptosis

(2017) Sehee Kim et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Hypertension Pandemic: An Evolutionary Perspective

(2017) Bernard C. Rossier et al.   PHYSIOLOGY

Mdivi-1 Protects Human W8B2+ Cardiac Stem Cells from Oxidative Stress and Simulated Ischemia-Reperfusion Injury

(2017) Ayeshah A. Rosdah et al.   STEM CELLS AND DEVELOPMENT

NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension

(2017) Hai-Jian Sun et al.   Cell Death & Disease

S-Nitrosylation of DRP1 Does Not Affect Enzymatic Activity and is Not Specific to Alzheimer's Disease

(2017) Blaise Bossy et al.   JOURNAL OF ALZHEIMERS DISEASE

Glucagon-like peptide-1 inhibits vascular smooth muscle cell dedifferentiation through mitochondrial dynamics regulation

(2016) Gloria Torres et al.   BIOCHEMICAL PHARMACOLOGY

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

AMP-activated protein kinase mediates mitochondrial fission in response to energy stress

(2016) E. Q. Toyama et al.   SCIENCE

Inhibition of Epac1 suppresses mitochondrial fission and reduces neointima formation induced by vascular injury

(2016) Hui Wang et al.   Scientific Reports

Decreasing mitochondrial fission diminishes vascular smooth muscle cell migration and ameliorates intimal hyperplasia

(2015) Li Wang et al.   CARDIOVASCULAR RESEARCH

Redox Homeostasis and Mitochondrial Dynamics

(2015) Peter H.G.M. Willems et al.   Cell Metabolism

Hypertension: Renin-Angiotensin-Aldosterone System Alterations

(2015) L. te Riet et al.   CIRCULATION RESEARCH

ROMO1 Is an Essential Redox-Dependent Regulator of Mitochondrial Dynamics

(2014) M. Norton et al.   Science Signaling

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

(2013) Juan Pablo Muñoz et al.   EMBO JOURNAL

Influence of glucose metabolism on vascular smooth muscle cell proliferation

(2013) Mario Chiong et al.   Vasa-European Journal of Vascular Medicine

Mitochondrial fission induced by platelet-derived growth factor regulates vascular smooth muscle cell bioenergetics and cell proliferation

(2013) Joshua K. Salabei et al.   Redox Biology

Angiotensin II-Induced Production of Mitochondrial Reactive Oxygen Species: Potential Mechanisms and Relevance for Cardiovascular Disease

(2012) Sergey I. Dikalov et al.   ANTIOXIDANTS & REDOX SIGNALING

S-Nitrosylation activates Cdk5 and contributes to synaptic spine loss induced by  -amyloid peptide

(2011) J. Qu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heterozygous Mutation of Opa1 in Drosophila Shortens Lifespan Mediated through Increased Reactive Oxygen Species Production

(2009) Sha Tang et al.   PLoS One

S-Nitrosylation of Drp1 Mediates β-Amyloid-Related Mitochondrial Fission and Neuronal Injury

(2009) Dong-Hyung Cho et al.   SCIENCE

Chemical Inhibition of the Mitochondrial Division Dynamin Reveals Its Role in Bax/Bak-Dependent Mitochondrial Outer Membrane Permeabilization

(2008) Ann Cassidy-Stone et al.   DEVELOPMENTAL CELL